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Any process that stops, prevents or reduces the frequency, rate or extent of cell activation. Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand. Any process that stops, prevents or reduces the frequency, rate or extent of coagulation. Any process that modulates the frequency, rate or extent of blood coagulation. The sequential process by which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers. Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation. Any process that modulates the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug. A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: negative regulation of platelet activation
Acc: GO:0010544
Aspect: Biological Process
Desc: Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.
Proteins in PDR annotated with:
   This term: 8 [Search]
   Term or descendants: 8 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0010544 - negative regulation of platelet activation (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle