Protein Overview: ESR2_RAT

General Information:
Name(s) found:	ESR2_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|6166156\|sp\|Q62986.2\|ESR2_RAT RecName: Full=Estrogen receptor beta; Short=ER-beta; AltName: Full=Nuclear receptor subfamily 3 group A member 2 [NCBI NR] Estrogen receptor beta OS=Rattus norvegicus GN=Esr2 PE=1 SV=2 [Swiss-Prot] Estrogen receptor beta (ER-beta) [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform 1 of Estrogen receptor beta [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SPLICE ISOFORM 1 OF ESTROGEN RECEPTOR BETA [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Esr2 Isoform 1 of Estrogen receptor beta [rat-ipi-250309-contam.fasta] Isoform 1 of Estrogen receptor beta OS=Rattus norvegicus GN=Esr2 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	530 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA][IEA] cytoplasm [IDA] mitochondrion [UNKNOWN][IDA] perikaryon [IDA] neuron projection [IDA]
Biological Process:	neuroprotection [IDA] vagina development [UNKNOWN] prostate gland epithelium morphogenesis [UNKNOWN] negative regulation of cell proliferation [UNKNOWN] uterus development [UNKNOWN] positive regulation of survival gene product expression [IDA] regulation of transcription, DNA-dependent [IEA] brain development [UNKNOWN] positive regulation of transcription from RNA polymerase II promoter [IDA] regulation of cell proliferation [UNKNOWN] epithelial cell maturation involved in prostate gland development [UNKNOWN] ovarian follicle development [UNKNOWN] behavioral fear response [IDA] learning or memory [IMP] negative regulation of androgen receptor signaling pathway [UNKNOWN] neuron migration [UNKNOWN] positive regulation of gene-specific transcription [IDA] negative regulation of behavior [IDA] positive regulation of apoptosis [UNKNOWN] negative regulation of epithelial cell proliferation [UNKNOWN][IDA] response to testosterone stimulus [IMP] estrogen receptor signaling pathway [UNKNOWN][TAS]
Molecular Function:	DNA binding [UNKNOWN] transcription factor activity [IEA] zinc ion binding [IEA] protein binding [UNKNOWN] transcription regulator activity [TAS] metal ion binding [IEA] estrogen receptor activity [IDA][IMP][TAS] steroid hormone receptor activity [IEA] hormone binding [IMP] sequence-specific DNA binding [IDA][IEA] steroid binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEIKNSPSSL SSPASYNCSQ SILPLEHGPI YIPSSYVDNR HEYSAMTFYS PAVMNYSVPG  60
   61 STSNLDGGPV RLSTSPNVLW PTSGHLSPLA THCQSSLLYA EPQKSPWCEA RSLEHTLPVN 120
  121 RETLKRKLSG SSCASPVTSP NAKRDAHFCP VCSDYASGYH YGVWSCEGCK AFFKRSIQGH 180
  181 NDYICPATNQ CTIDKNRRKS CQACRLRKCY EVGMVKCGSR RERCGYRIVR RQRSSSEQVH 240
  241 CLSKAKRNGG HAPRVKELLL STLSPEQLVL TLLEAEPPNV LVSRPSMPFT EASMMMSLTK 300
  301 LADKELVHMI GWAKKIPGFV ELSLLDQVRL LESCWMEVLM VGLMWRSIDH PGKLIFAPDL 360
  361 VLDRDEGKCV EGILEIFDML LATTSRFREL KLQHKEYLCV KAMILLNSSM YPLASANQEA 420
  421 ESSRKLTHLL NAVTDALVWV IAKSGISSQQ QSVRLANLLM LLSHVRHISN KGMEHLLSMK 480
  481 CKNVVPVYDL LLEMLNAHTL RGYKSSISGS ECSSTEDSKN KESSQNLQSQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.93

Protein Overview: ESR2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: