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Protein Overview: ATZN_ECOLI

General Information:
Name(s) found: ATZN_ECOLI [Swiss-Prot]
Description(s) found:
Found 8 descriptions.
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  • Lead, cadmium, zinc and mercury-transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5) - Escherichia coli [Swiss-Prot]
    • Organism: Escherichia coli
    Length: 732 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTPDNHGKK APQFAAFKPL TTVQNANDCC CDGACSSTPT LSENVSGTRY SWKVSGMDCA  60
   61 ACARKVENAV RQLAGVNQVQ VLFATEKLVV DADNDIRAQV ESALQKAGYS LRDEQAAEEP 120
  121 QASRLKENLP LITLIVMMAI SWGLEQFNHP FGQLAFIATT LVGLYPIARQ ALRLIKSGSY 180
  181 FAIETLMSVA AIGALFIGAT AEAAMVLLLF LIGERLEGWA ASRARQGVSA LMALKPETAT 240
  241 RLRKGEREEV AINSLRPGDV IEVAAGGRLP ADGKLLSPFA SFDESALTGE SIPVERATGD 300
  301 KVPAGATSVD RLVTLEVLSE PGASAIDRIL KLIEEAEERR APIERFIDRF SRIYTPAIMA 360
  361 VALLVTLVPP LLFAASWQEW IYKGLTLLLI GCPCALVIST PAAITSGLAA AARRGALIKG 420
  421 GAALEQLGRV TQVAFDKTGT LTVGKPRVTA IHPATGISES ELLTLAAAVE QGATHPLAQA 480
  481 IVREAQVAEL AIPTAESQRA LVGSGIEAQV NGERVLICAA GKHPADAFTG LINELESAGQ 540
  541 TVVLVVRNDD VLGVIALQDT LRADAATAIS ELNALGVKGV ILTGDNPRAA AAIAGELGLE 600
  601 FKAGLLPEDK VKAVTELNQH APLAMVGDGI NDAPAMKAAA IGIAMGSGTD VALETADAAL 660
  661 THNHLRGLVQ MIELARATHA NIRQNITIAL GLKGIFLVTT LLGMTGLWLA VLADTGATVL 720
  721 VTANALRLLR RR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..118] PSI-BLAST 8.0 Metal ion-transporting ATPase ZntA, N-terminal domain
    2 View Details [119..732] PSI-BLAST 87.09691 Proton ATPase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • copper chaperone activity
    		•  5.99007447506957 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  5.4007166857771 bayes_pls_golite062009
  • copper ion transmembrane transporter activity
    		•  5.18510514935825 bayes_pls_golite062009
  • copper-exporting ATPase activity
    		•  5.04749761961029 bayes_pls_golite062009
  • copper-transporting ATPase activity
    		•  5.03252922496602 bayes_pls_golite062009
  • copper ion binding
    		•  5.01875130037421 bayes_pls_golite062009
  • metallochaperone activity
    		•  4.85524337397713 bayes_pls_golite062009
  • transition metal ion transmembrane transporter activity
    		•  4.79570221435856 bayes_pls_golite062009
  • copper-dependent protein binding
    		•  4.71729267115962 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  4.61622753861072 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.52484959112186 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  4.12792340516867 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  4.10264569844449 bayes_pls_golite062009
  • di-, tri-valent inorganic cation transmembrane transporter activity
    		•  3.70964017127302 bayes_pls_golite062009
  • superoxide dismutase copper chaperone activity
    		•  3.50705492219116 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
    		•  3.27250923701445 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of ions
    		•  2.98847682261773 bayes_pls_golite062009
  • transition metal ion binding
    		•  2.6049784579434 bayes_pls_golite062009
  • transporter activity
    		•  2.43435890488191 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.32163502360862 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.28845421748925 bayes_pls_golite062009
  • metal ion binding
    		•  1.84981492985167 bayes_pls_golite062009
  • cation binding
    		•  1.84981492985167 bayes_pls_golite062009
  • binding
    		•  1.84926272403445 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  1.62116507842838 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  1.61680623728503 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  1.59572740343301 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  1.5925429451548 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  1.59219836319916 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.53883152283038 bayes_pls_golite062009
  • ATPase activity
    		•  1.12732384636594 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  1.1123150216263 bayes_pls_golite062009
  • ion binding
    		•  1.07409701266582 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  1.04872000948037 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  1.03270166246194 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  1.02977205960797 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  1.02520458852568 bayes_pls_golite062009
  • hydrolase activity
    		•  0.887060142135599 bayes_pls_golite062009
  • cation-transporting ATPase activity
    		•  0.75722873989123 bayes_pls_golite062009
  • protein binding
    		•  0.736752132095517 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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