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Protein Overview: tbx-9

General Information:
Name(s) found: tbx-9 / CE36892 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00006546 locus:tbx-9 T-box transcription factor tbx-9 status:Confirmed UniProt:Q22289 protein_id:CAA82575.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 292 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article][ISSLink to PubMed article]
    transcription factor complex [ISSLink to PubMed article]
    Biological Process: nematode larval development [IMPLink to PubMed articleLink to PubMed article]
    post-embryonic body morphogenesis [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed article]
    regulation of transcription, DNA-dependent [IEALink to PubMed article]
    growth [IMPLink to PubMed article]
    regulation of transcription from RNA polymerase II promoter [ISSLink to PubMed article]
    Molecular Function: transcription factor activity [IEALink to PubMed article]
    RNA polymerase II transcription factor activity, enhancer binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKVKVSIEG SQETLWKIFH AEVNEMIVTK NGRKLFPKLE YIVEGLDENK LYAIMLQLQP  60
   61 VGESRFKFSG GKWQETGKAE KQVDAKKMWH ADGVRKGSDW MWSSICFDRV KISNYSESNN 120
  121 ASMIYLNSMH KYIPVLTIYE SPSESPFCVP QSSNQIVATA KFPHTEFIAV TAYQNQKITD 180
  181 LKIKHNSFAK GFRDGNLSRK RRSPSYSDGS NSQSPSPKSR SPPEVAPLQS MPPINPFLFY 240
  241 FPHMLSENLP VQFPFAFPFL SPLPSTPSSS SSELSIVKEE DQEVEEDIDI VG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..203] PSI-BLAST 75.154902 T-box protein 3, tbx3
    2 View Details [204..292] MSA 1.152995 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  5.42929256050781 bayes_pls_golite062009
  • DNA binding
    		•  5.31133900263778 bayes_pls_golite062009
  • nucleic acid binding
    		•  5.16722510757739 bayes_pls_golite062009
  • transcription factor activity
    		•  4.50526425463039 bayes_pls_golite062009
  • binding
    		•  3.82913410895101 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.81812565096059 bayes_pls_golite062009
  • protein binding
    		•  2.61625563263605 bayes_pls_golite062009
  • transcription activator activity
    		•  2.56828839945617 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.23604897773023 bayes_pls_golite062009
  • DNA strand annealing activity
    		•  1.36275472058409 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.27337392672914 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.6498675574078 bayes_pls_golite062009
  • chromatin binding
    		•  0.63177553202971 bayes_pls_golite062009
  • transcription factor binding
    		•  0.628837188707778 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.62643527396553 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  0.0996675597396202 bayes_pls_golite062009
  • protein dimerization activity
    		•  0.0889583851427092 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle