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Protein Overview: cpz-1

General Information:
Name(s) found: cpz-1 / CE36646 [WormBase]
Description(s) found:
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  • WBGene00000788 locus:cpz-1 status:Confirmed UniProt:G5EGP8 protein_id:CCD70407.1 [WormBase]
  • gi|71985272|ref|NP_491023.2| CathePsin Z family member (cpz-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|52078128|tpg|DAA01510.1| TPA_exp: cathepsin Z-like enzyme [Caenorhabditis elegans] [NCBI NR]
  • gi|47270758|gb|AAB54210.2| Cathepsin z protein 1 [Caenorhabditis elegans] [NCBI NR]
  • Cathepsin z protein 1 [Caenorhabditis elegans]gi|52078128|tpg|DAA01510.1| TPA: cathepsin Z-like enzyme; CPZ-1 [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • CE36646 WBGene00000788 locus:cpz-1 cysteine proteinase status:Confirmed TR:O01850 protein_id:AAB54210.2 [wormpep150.fasta]
  • 36646 WBGene00000788 locus:cpz-1 cysteine proteinase status:Confirmed TR:O01850 protein_id:AAB54210.2 [wormpep130-phg-ecoli-orf-rand.fasta]
  • CE36646 WBGene00000788 locus:cpz-1 cysteine proteinase status:Confirmed UniProt:O01850_CAEEL protein_id:AAB54210.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE36646 WBGene00000788 locus:cpz-1 cysteine proteinase status:Confirmed UniProt:O01850_CAEEL protein_id:AAB54210.2| [wormORF-contam.fasta]
  • TPA_exp: cathepsin Z-like enzyme [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CathePsin Z family member (cpz-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Cathepsin z protein 1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE36646 WBGene00000788 locus:cpz-1 cysteine proteinase status:Confirmed UniProt:O01850 protein_id:AAB54210.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE36646 WBGene00000788 locus:cpz-1 cysteine proteinase status:Confirmed UniProt:G5EGP8 protein_id:CCD70407.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE36646 WBGene00000788 locus:cpz-1 status:Confirmed UniProt:G5EGP8 protein_id:CCD70407.1 [wormpep246-ecoli-contam.fasta]
  • CathePsin Z OS=Caenorhabditis elegans GN=cpz-1 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 306 amino acids

    Gene Ontology:
    Cellular Component: extracellular matrix [IDALink to PubMed article]
    Biological Process: molting cycle, protein-based cuticle [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed article]
    post-embryonic body morphogenesis [IMPLink to PubMed article]
    proteolysis [IEALink to PubMed article]
    growth [IMPLink to PubMed article]
    Molecular Function: cysteine-type endopeptidase activity [IEALink to PubMed article]
    cysteine-type peptidase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRTFVLLLAL CAICILASSA YGKVRKYSNR NRYNLKGCYK QTGRVFEHKR YDRIYETEDF  60
   61 DSEDLPKTWD WRDANGINYA SADRNQHIPQ YCGSCWAFGA TSALADRINI KRKNAWPQAY 120
  121 LSVQEVIDCS GAGTCVMGGE PGGVYKYAHE HGIPHETCNN YQARDGKCDP YNRCGSCWPG 180
  181 ECFSIKNYTL YKVSEYGTVH GYEKMKAEIY HKGPIACGIA ATKAFETYAG GIYKEVTDED 240
  241 IDHIISVHGW GVDHESGVEY WIGRNSWGEP WGEHGWFKIV TSQYKNAGSK YNLKIEEDCV 300
  301 WADPIV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..58] MSA 5.488996 View MSA. No confident structure predictions are available.
    2 View Details [59..306] PSI-BLAST 45.30103 (Pro)cathepsin X

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • peptidase activity
    		•  2.8192612691912 bayes_pls_golite062009
  • hydrolase activity
    		•  2.77636082652282 bayes_pls_golite062009
  • cysteine-type peptidase activity
    		•  2.71117522993364 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  2.55227247835105 bayes_pls_golite062009
  • cysteine-type endopeptidase activity
    		•  1.95802900199539 bayes_pls_golite062009
  • endopeptidase activity
    		•  1.66703380008241 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.12653729823589 bayes_pls_golite062009
  • catalytic activity
    		•  1.05972260874031 bayes_pls_golite062009
  • binding
    		•  1.05436445615005 bayes_pls_golite062009
  • protein binding
    		•  0.896934807256194 bayes_pls_golite062009
  • tubulin binding
    		•  0.80007793113729 bayes_pls_golite062009
  • microtubule binding
    		•  0.752289145309061 bayes_pls_golite062009
  • small conjugating protein-specific protease activity
    		•  0.500110970732392 bayes_pls_golite062009
  • structural molecule activity
    		•  0.102555314244558 bayes_pls_golite062009
  • ubiquitin-specific protease activity
    		•  0.0101379718864654 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle