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View Structure Prediction Details

Protein: cpz-1
Organism: Caenorhabditis elegans
Length: 306 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cpz-1.

Description E-value Query
Range
Subject
Range
gi|125811035, gi... - gi|54636903|gb|EAL26306.1| GA20520-PA [Drosophila pseudoobscura], gi|125811035|ref|XP_001361728.1| G...
270.0 [0..2] [306..49]

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Predicted Domain #1
Region A:
Residues: [1-58]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRTFVLLLAL CAICILASSA YGKVRKYSNR NRYNLKGCYK QTGRVFEHKR YDRIYETE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [59-306]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DFDSEDLPKT WDWRDANGIN YASADRNQHI PQYCGSCWAF GATSALADRI NIKRKNAWPQ  60
   61 AYLSVQEVID CSGAGTCVMG GEPGGVYKYA HEHGIPHETC NNYQARDGKC DPYNRCGSCW 120
  121 PGECFSIKNY TLYKVSEYGT VHGYEKMKAE IYHKGPIACG IAATKAFETY AGGIYKEVTD 180
  181 EDIDHIISVH GWGVDHESGV EYWIGRNSWG EPWGEHGWFK IVTSQYKNAG SKYNLKIEED 240
  241 CVWADPIV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.30103
Match: 1deuA
Description: (Pro)cathepsin X
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 2.8192612691912 bayes_pls_golite062009
hydrolase activity 2.77636082652282 bayes_pls_golite062009
cysteine-type peptidase activity 2.71117522993364 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 2.55227247835105 bayes_pls_golite062009
cysteine-type endopeptidase activity 1.95802900199539 bayes_pls_golite062009
endopeptidase activity 1.66703380008241 bayes_pls_golite062009
cytoskeletal protein binding 1.12653729823589 bayes_pls_golite062009
catalytic activity 1.05972260874031 bayes_pls_golite062009
binding 1.05436445615005 bayes_pls_golite062009
protein binding 0.896934807256194 bayes_pls_golite062009
tubulin binding 0.80007793113729 bayes_pls_golite062009
microtubule binding 0.752289145309061 bayes_pls_golite062009
small conjugating protein-specific protease activity 0.500110970732392 bayes_pls_golite062009
structural molecule activity 0.102555314244558 bayes_pls_golite062009
ubiquitin-specific protease activity 0.0101379718864654 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle