Protein Overview: AIM3

General Information:
Name(s) found:	AIM3 / YBR108W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|83287900\|sp\|P38266.2\|YBV8_YEAST RecName: Full=Uncharacterized protein YBR108W [NCBI NR] gi\|50234882\|ref\|NP_009666.2\| Protein interacting with Rsv167p; null mutant displays decreased frequency of mitochondrial genome loss (petite formation) and severe growth defect in minimal glycerol media; Aim3p [Saccharomyces cerevisiae] [NCBI NR] Uncharacterized protein YBR108W OS=Saccharomyces cerevisiae GN=YBR108W PE=1 SV=2 [Swiss-Prot] Weak similarity to R.norvegicus atrophin-1 related protein [mips] Protein interacting with Rvs167p; null mutant is viable and displays elevated frequency of mitochondrial genome loss [SGD] YBR108W SGDID:S0000312, Chr II from 454816-457659, Uncharacterized ORF [10112005cervSGD.fasta] Ybr108wp [Saccharomyces cerevisiae] [nrdb_11152004_Chlamydomonas] YBR108W SGDID:S000000312, Chr II from 454816-457659, Uncharacterized ORF, "Protein interacting with Rsv167p" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] YBR108W SGDID:S000000312, Chr II from 454816-457659, Uncharacterized ORF, "Protein interacting with Rsv167p; null mutant displays decreased frequency of mitochondrial genome loss (petite formation) and severe growth defect in minimal glycerol media" [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta] YBR108W SGDID:S000000312, Chr II from 454816-457659, Uncharacterized ORF, "Protein interacting with Rvs167p; YBR108W is not an essential gene" [yeast-200209-contam.fasta] AIM3 SGDID:S000000312, Chr II from 454816-457659, Verified ORF, "Protein interacting with Rvs167p; null mutant is viable and displays elevated frequency of mitochondrial genome loss" [SGD_S-cerevisiae_na_05-08-2009_con_reversed.fasta] Protein interacting with Rsv167p; Ybr108wp [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Uncharacterized protein YBR108W [nr-271106-contam.fasta] [chemostatdb.fasta]
Organism:	Saccharomyces cerevisiae
Length:	947 amino acids
Gene Ontology:
Cellular Component:	membrane raft [IDA]
Biological Process:	biological_process [ND]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGFWENNKDS ITSGLKSAGK YGYQGTKYVA KTGYKASKKH YNNSKARRER KSGKKNSSDE  60
   61 EYDSEDEMEY ERKPTDIRSL KDPKSFPPPP LKPGQKTYTG QQQQQMPNGQ ASYAFQGAYQ 120
  121 GQPGAGSTEQ SQYAQPQYNQ YPQQQLQQGV MPQQQQLQQG VVPQQPPIYG EQVPPYGSNS 180
  181 NATSYQSLPQ QNQPQNAIPS QVSLNSASQQ STGFVSQNLQ YGTQSSNPAP SPSFQNGLQC 240
  241 HQQPQYVSHG STNLGQSQFP SGQQQQPTTQ FGQQVLPSPA QPQQQQQGQP LPPPRGQVIL 300
  301 PAPGEPLSNG FGQQQQQQQQ QQQPLNQNNA LLPQMNVEGV SGMAAVQPVY GQAMSSTTNM 360
  361 QDSNPSYGAS PMQGQPPVGG QPPVPVRMQP QPPQPMQQGN IYPIEPSLDS TGSTPHFEVT 420
  421 PFDPDAPAPK PKIDIPTVDV SSLPPPPTHR DRGAVVHQEP APSGKIQPNT TSSAASLPAK 480
  481 HSRTTTADNE RNSGNKENDE STSKSSILGH YDVDANIMPP PKPFRHGLDS VPSEHTTKNA 540
  541 PERAVPILPP RNNVEPPPPP SRGNFERTES VLSTNAANVQ EDPISNFLPP PKPFRHTETK 600
  601 QNQNSKASPV EMKGEVLPGH PSEEDRNVEP SLVPQSKPQS QSQFRRAHME TQPIQNFQPP 660
  661 PKPFRRSQSS NSSDSSYTID GPEANHGRGR GRIAKHHDGD EYNPKSENST ENGRLGDAPN 720
  721 SFIRKRAPTP PAPSRSEKLH EGTITSEVDS SKDANKYEKS IPPVTSSIQA QQSTKKAPPP 780
  781 VVKPKPRNFS LKANEYPKEL TREATGQDEV LNSITNELSH IKLRKTNVNL EKLGGSKKVK 840
  841 DSSPVPSDLD EKYVSASGSI TPPRPPPSRS SPKKVPPVVP KKNDNLKKKP PVVPKKKPLL 900
  901 KSLEPRPIEM ERAYSGDISA ADDNLNPFER YKRNVVPQED DRLHKLK

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Krogan NJ, et al. (2006)		AIM3 BAR1 COA4 GYL1 GYP5 HNT1 KIN2 MEF2 NCP1 PCL10 PRP28 RVS161 RVS167 SAE2 SLK19 TIM21 VPS15

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MLP2	#03 Alpha Factor Prep1-TiO2 Flowthrough	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	RVS167	AIM3	2	Unpublished Fields Lab Data
View Screen	SWI5	AIM3	1	Unpublished Fields Lab Data
View Screen	SAM35	AIM3	1	Unpublished Fields Lab Data
View Screen	EST1	AIM3	1	Unpublished Fields Lab Data
View Screen	SPT21	AIM3	1	Unpublished Fields Lab Data

Microscopy / Localization Data

New Feature: Upload Your Own Microscopy Data

No microscopy data found in the PDR for this protein.

Protein Structure Data

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)