Protein Overview: GPI14

General Information:
Name(s) found:	GPI14 / YJR013W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|42742257\|ref\|NP_012547.2\| Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I, involved in GPI anchor biosynthesis, requires Pbn1p for function; homolog of mammalian PIG-M; Gpi14p [Saccharomyces cerevisiae] [NCBI NR] gi\|110825723\|sp\|P47088.2\|GPI14_YEAST RecName: Full=GPI mannosyltransferase 1; AltName: Full=GPI mannosyltransferase I; Short=GPI-MT-I; AltName: Full=Glycosylphosphatidylinositol-anchor biosynthesis protein 14 [NCBI NR] GPI mannosyltransferase 1 OS=Saccharomyces cerevisiae GN=GPI14 PE=1 SV=2 [Swiss-Prot] GPI14 Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I, involved in GPI anchor biosynthesis [mips] Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I, involved in GPI anchor biosynthesis, requires Pbn1p for function; homolog of mammalian PIG-M [SGD] PMH1 SGDID:S0003774, Chr X from 460296-461507, Uncharacterized ORF [yeastflysequest.fasta] Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I, involved in GPI anchor biosynthesis; homolog of mammalian PIG-M [Saccharomyces cerevisiae] [nrdb_11152004_Chlamydomonas] GPI14 SGDID:S000003774, Chr X from 460296-461507, Uncharacterized ORF, "Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I, involved in GPI anchor biosynthesis, requires Pbn1p for function; homolog of mammalian PIG-M" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] GPI14 SGDID:S000003774, Chr X from 460375-461586, Uncharacterized ORF, "Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I, involved in GPI anchor biosynthesis, requires Pbn1p for function; homolog of mammalian PIG-M" [yeast-contam.fasta] GPI14 SGDID:S000003774, Chr X from 460375-461586, Verified ORF, "Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I, involved in GPI anchor biosynthesis, requires Pbn1p for function; homolog of mammalian PIG-M" [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta] GPI14 SGDID:S000003774, Chr X from 460374-461585, Verified ORF, "Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I, involved in GPI anchor biosynthesis, requires Pbn1p for function; homolog of mammalian PIG-M" [yeast-200209-contam.fasta] Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I, involved in GPI anchor biosynthesis, requires Pbn1p for function; homolog of mammalian PIG-M; Gpi14p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] GPI mannosyltransferase 1 (GPI mannosyltransferase I) (GPI-MT-I) (Glycosylphosphatidylinositol-anchor biosynthesis protein 14) [nr-271106-contam.fasta] [chemostatdb.fasta] GPI mannosyltransferase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GPI14 PE=1 SV=2 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] GPI14 SGDID:S000003774, Chr X from 460382-461593, Genome Release 64-1-1, Verified ORF, "Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I, involved in GPI anchor biosynthesis, requires Pbn1p for function; homolog of mammalian PIG-M" [yeast-030211-contam.fasta] GPI14 SGDID:S000003774, Chr X from 460382-461593, Genome Release 64-2-1, Verified ORF, "Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I; involved in GPI anchor biosynthesis, requires Pbn1p for function; homolog of mammalian PIG-M" [20141208_orf_trans.fasta] TR4905\|c0_g1_i1\|g.3441 ORF TR4905\|c0_g1_i1\|g.3441 TR4905\|c0_g1_i1\|m.3441 type:complete len:404 (+) TR4905\|c0_g1_i1:80-1291(+) [Y12_S_cerevisiae-Sep2015-contam.fasta] YJR013W SGDID:S000003774, Chr X from 460382-461593, Genome Release 64-1-1, Verified ORF, "Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I, involved in GPI anchor biosynthesis, requires Pbn1p for function; homolog of mammalian PIG-M" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta] asmbl_5677\|g.4106 ORF asmbl_5677\|g.4106 asmbl_5677\|m.4106 type:complete len:404 (+) asmbl_5677:74-1285(+) [Y12_Trinity_v2_2_0_PASA_6May2016-contam.fasta] ID=asmbl_5680\|g.3401 ORF ID=asmbl_5680\|g.3401 ID=asmbl_5680\|m.3401 type:complete len:404 (+) ID=asmbl_5680:78-1289(+) [Y12_quiver_Trinity_v2_2_0_PASA_2June2016-contam.fasta]
Organism:	Saccharomyces cerevisiae
Length:	403 amino acids
Gene Ontology:
Cellular Component:	endoplasmic reticulum membrane [ISS]
Biological Process:	fungal-type cell wall organization [IMP] GPI anchor biosynthetic process [IMP][ISS]
Molecular Function:	mannosyltransferase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTGEEWGLTV LSFLVRVGFF LFGIYQDANF KVRYTDIDYF VFHDAAKYVY EGKSPYARDT  60
   61 YRYTPLLSWL LVPNHYFGWF HLGKVIFVIF DLVTGLIIMK LLNQAISRKR ALILESIWLL 120
  121 NPMVITISTR GNAESVLCCL IMFTLFFLQK SRYTLAGILY GLSIHFKIYP IIYCIPIAIF 180
  181 IYYNKRNQGP RTQLTSLLNI GLSTLTTLLG CGWAMYKIYG YEFLDQAYLY HLYRTDHRHN 240
  241 FSVWNMLLYL DSANKENGES NLSRYAFVPQ LLLVLVTGCL EWWNPTFDNL LRVLFVQTFA 300
  301 FVTYNKVCTS QYFVWYLIFL PFYLSRTHIG WKKGLLMATL WVGTQGIWLS QGYYLEFEGK 360
  361 NVFYPGLFIA SVLFFVTNVW LLGQFITDIK IPTQPTVSNK KNN

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Qiu et al. (2008)		ERI1 GPI11 GPI14 GPI19

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	GPI14	FRT2	2	Hazbun TR, et al. (2003)
View Screen	GPI14	SSY1	2	Hazbun TR, et al. (2003)
View Screen	GPI14	RGS2	2	Hazbun TR, et al. (2003)
View Screen	GPI14	NFI1	2	Hazbun TR, et al. (2003)
View Screen	GPI14	GNP1	2	Hazbun TR, et al. (2003)
View Screen	GPI14	ATG32	2	Hazbun TR, et al. (2003)
View Screen	GPI14	SPO19	2	Hazbun TR, et al. (2003)
View Screen	GPI14	MGA2	2	Hazbun TR, et al. (2003)
View Screen	GPI14	PRM3	2	Hazbun TR, et al. (2003)
View Screen	GPI14	GTT1	2	Hazbun TR, et al. (2003)
View Screen	GPI14	KRE6	2	Hazbun TR, et al. (2003)
View Screen	GPI14	CHS3	2	Hazbun TR, et al. (2003)
View Screen	GPI14	GAP1	2	Hazbun TR, et al. (2003)
View Screen	GPI14	AGP1	2	Hazbun TR, et al. (2003)
View Screen	GPI14	YCR007C	2	Hazbun TR, et al. (2003)
View Screen	GPI14	YIP5	2	Hazbun TR, et al. (2003)
View Screen	GPI14	ARE1	2	Hazbun TR, et al. (2003)
View Screen	GPI14	HFD1	2	Hazbun TR, et al. (2003)
View Screen	GPI14	PAR32	2	Hazbun TR, et al. (2003)
View Screen	GPI14	YNL115C	2	Hazbun TR, et al. (2003)
View Screen	GPI14	BAP3	2	Hazbun TR, et al. (2003)
View Screen	GPI14	ZRG17	2	Hazbun TR, et al. (2003)

Microscopy / Localization Data

New Feature: Upload Your Own Microscopy Data

	PROTEIN(S)	PUBLICATION
View Data	GPI14 and TRX3	Hazbun TR, et al. (2003)
View Data	GPI14 and SPC42	Hazbun TR, et al. (2003)
View Data	GPI14 and SPC42	Unpublished Data
View Data	GPI14	Huh WK, et al. (2003)

Protein Structure Data

[What does the above image mean?]
[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..235]	MSA	22.168997	View MSA. No confident structure predictions are available.
2	View Details	[236..324]	MSA	3.108993	View MSA. No confident structure predictions are available.
3	View Details	[325..403]	deduced	N/A	No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2