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Protein Overview: C86A8_ARATH

General Information:
Name(s) found: C86A8_ARATH [Swiss-Prot]
Description(s) found:
Found 17 descriptions.
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  • Cytochrome P450 86A8 OS=Arabidopsis thaliana GN=CYP86A8 PE=2 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 537 amino acids

    Gene Ontology:
    Cellular Component: endomembrane system [IEA]
    Biological Process: fatty acid metabolic process [IDA]
    Molecular Function: oxygen binding [ISS]
    fatty acid (omega-1)-hydroxylase activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEISTALMIL SAITAYFLWL TFISRCLKGP RVWPILGSLP GLIENCERMH DWISDNLRAC  60
   61 SGTYQTCICA IPFLAKKQGL VTVTCDPRNL EHILKNRFDN YPKGPTWQAV FHDLLGQGIF 120
  121 NSDGDTWLFQ RKTAALEFTT RTLRQAMARW VNRAIKLRFL PILENARLGS EPIDLQDLLL 180
  181 RLTFDNICGL TFGKDPRTCA PGLPVNTFAV AFDRATEASL QRFILPEILW KFKRWLRLGL 240
  241 EVSLTRSLVQ VDNYLSEIIT TRKEEMMTQH NNGKHHDDLL SRFIKKKESY SDETLQRVAL 300
  301 NFILAGRDTS SVALSWFFWL ITQHPAIEDK ILREICTVLV ETRGDDVALW TDEPLSCEEL 360
  361 DRLVFLKAAL SETLRLYPSV PEDSKRAVKD DVLPDGTFVP AGSSITYSIY SAGRMKSTWG 420
  421 EDCLEFKPER WISQSDGGRF INHDPFKFVA FNAGPRICLG KDLAYLQMKS IASAVLLRHR 480
  481 LTVVTGHKVE QKMSLTLFMK YGLLVNVHER DLTAIAADLR ECKSNVVNDG VGNGVSS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..537] PSI-BLAST 87.69897 Crystal Structure of Human Microsomal P450 3A4

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • arachidonic acid monooxygenase activity
    		•  6.76823710927794 bayes_pls_golite062009
  • fatty acid (omega-1)-hydroxylase activity
    		•  6.3313834755701 bayes_pls_golite062009
  • monooxygenase activity
    		•  5.57229509004705 bayes_pls_golite062009
  • steroid hydroxylase activity
    		•  5.04794778387361 bayes_pls_golite062009
  • arachidonic acid epoxygenase activity
    		•  4.80764258881036 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
    		•  3.68151610133025 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
    		•  2.56821164444595 bayes_pls_golite062009
  • oxidoreductase activity
    		•  2.35847923992364 bayes_pls_golite062009
  • retinoic acid 4-hydroxylase activity
    		•  1.90796041033974 bayes_pls_golite062009
  • oxysterol 7-alpha-hydroxylase activity
    		•  1.71732865382274 bayes_pls_golite062009
  • flavonoid 3'-monooxygenase activity
    		•  1.71233606135238 bayes_pls_golite062009
  • electron carrier activity
    		•  1.48516712188486 bayes_pls_golite062009
  • arachidonic acid 11,12-epoxygenase activity
    		•  1.48500938886158 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
    		•  1.46109575978397 bayes_pls_golite062009
  • binding
    		•  1.0881336564542 bayes_pls_golite062009
  • ecdysteroid 25-hydroxylase activity
    		•  0.89030345144459 bayes_pls_golite062009
  • retinoic acid binding
    		•  0.851040588981921 bayes_pls_golite062009
  • catalytic activity
    		•  0.608111453189583 bayes_pls_golite062009
  • oxygen binding
    		•  0.3117502273138 bayes_pls_golite062009
  • cholesterol monooxygenase (side-chain-cleaving) activity
    		•  0.276594551871869 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen
    		•  0.238731261808013 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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