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View Structure Prediction Details

Protein: C86A8_ARATH
Organism: Arabidopsis thaliana
Length: 537 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for C86A8_ARATH.

Description E-value Query
Range		 Subject
Range
gi|12231914 - gi|12231914|gb|AAG49315.1|AF315465_1 flavonoid 3'-hydroxylase [Pelargonium x hortorum]
 364.0 [0..1] [516..8]

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Predicted Domain #1
Region A:
Residues: [1-537] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEISTALMIL SAITAYFLWL TFISRCLKGP RVWPILGSLP GLIENCERMH DWISDNLRAC  60
   61 SGTYQTCICA IPFLAKKQGL VTVTCDPRNL EHILKNRFDN YPKGPTWQAV FHDLLGQGIF 120
  121 NSDGDTWLFQ RKTAALEFTT RTLRQAMARW VNRAIKLRFL PILENARLGS EPIDLQDLLL 180
  181 RLTFDNICGL TFGKDPRTCA PGLPVNTFAV AFDRATEASL QRFILPEILW KFKRWLRLGL 240
  241 EVSLTRSLVQ VDNYLSEIIT TRKEEMMTQH NNGKHHDDLL SRFIKKKESY SDETLQRVAL 300
  301 NFILAGRDTS SVALSWFFWL ITQHPAIEDK ILREICTVLV ETRGDDVALW TDEPLSCEEL 360
  361 DRLVFLKAAL SETLRLYPSV PEDSKRAVKD DVLPDGTFVP AGSSITYSIY SAGRMKSTWG 420
  421 EDCLEFKPER WISQSDGGRF INHDPFKFVA FNAGPRICLG KDLAYLQMKS IASAVLLRHR 480
  481 LTVVTGHKVE QKMSLTLFMK YGLLVNVHER DLTAIAADLR ECKSNVVNDG VGNGVSS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 87.69897
Match: 1tqnA
Description: Crystal Structure of Human Microsomal P450 3A4
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
arachidonic acid monooxygenase activity 6.76823710927794 bayes_pls_golite062009
fatty acid (omega-1)-hydroxylase activity 6.3313834755701 bayes_pls_golite062009
monooxygenase activity 5.57229509004705 bayes_pls_golite062009
steroid hydroxylase activity 5.04794778387361 bayes_pls_golite062009
arachidonic acid epoxygenase activity 4.80764258881036 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 3.68151610133025 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 2.56821164444595 bayes_pls_golite062009
oxidoreductase activity 2.35847923992364 bayes_pls_golite062009
retinoic acid 4-hydroxylase activity 1.90796041033974 bayes_pls_golite062009
oxysterol 7-alpha-hydroxylase activity 1.71732865382274 bayes_pls_golite062009
flavonoid 3'-monooxygenase activity 1.71233606135238 bayes_pls_golite062009
electron carrier activity 1.48516712188486 bayes_pls_golite062009
arachidonic acid 11,12-epoxygenase activity 1.48500938886158 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1.46109575978397 bayes_pls_golite062009
binding 1.0881336564542 bayes_pls_golite062009
ecdysteroid 25-hydroxylase activity 0.89030345144459 bayes_pls_golite062009
retinoic acid binding 0.851040588981921 bayes_pls_golite062009
catalytic activity 0.608111453189583 bayes_pls_golite062009
oxygen binding 0.3117502273138 bayes_pls_golite062009
cholesterol monooxygenase (side-chain-cleaving) activity 0.276594551871869 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen 0.238731261808013 bayes_pls_golite062009
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