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Protein Overview: UBC18_ARATH

General Information:
Name(s) found: UBC18_ARATH [Swiss-Prot]
Description(s) found:
Found 16 descriptions.
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  • Probable ubiquitin-conjugating enzyme E2 18 OS=Arabidopsis thaliana GN=UBC18 PE=2 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 161 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: ubiquitin-dependent protein catabolic process [TAS]
    Molecular Function: ubiquitin-protein ligase activity [ISS]
    small conjugating protein ligase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSSSSPSRK ALSKIACNRL QKELSEWQVN PPTGFKHRVT DNLQKWVIEV TGAPGTLYAN  60
   61 ETYNLQVEFP QHYPMEAPQV IFVPPAPLHP HIYSNGHICL DILYDSWSPA MTVSSVCISI 120
  121 LSMLSSSPEK QRPTDNDRYV KNCKNGRSPK ETRWWFHDDK V

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..161] PSI-BLAST 48.30103 The 1.1A crystallographic structure of ubiquitin-conjugating enzyme (ubc-2) from Caenorhabditis elegans: functional and evolutionary significance

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • HLH domain binding
    		•  8.10904818707269 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  7.07009148420636 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  7.03976510657099 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  6.00007452476109 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  5.06177413452771 bayes_pls_golite062009
  • SUMO ligase activity
    		•  3.88357560284404 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.21355731489173 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.13970605403492 bayes_pls_golite062009
  • DNA binding
    		•  1.95596447916631 bayes_pls_golite062009
  • ligase activity
    		•  1.88059319399119 bayes_pls_golite062009
  • protein binding
    		•  1.77678273247394 bayes_pls_golite062009
  • binding
    		•  1.75350658654805 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.5236035191291 bayes_pls_golite062009
  • catalytic activity
    		•  0.891402822028799 bayes_pls_golite062009
  • NEDD8 ligase activity
    		•  0.715654744941217 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.58835335751383 bayes_pls_golite062009
  • kinase activity
    		•  0.519703305315987 bayes_pls_golite062009
  • protein kinase activity
    		•  0.443948654247666 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.373779304908933 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.182854082413338 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.122859425935324 bayes_pls_golite062009
  • transferase activity
    		•  0.0984525836903841 bayes_pls_golite062009
  • transcription activator activity
    		•  0.0138208971172455 bayes_pls_golite062009
  • transcription factor binding
    		•  0.0104967529560147 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.86

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle