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Protein Overview: CSN4_ARATH

General Information:
Name(s) found: CSN4_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|98960965|gb|ABF58966.1| At5g42970 [Arabidopsis thaliana] [NCBI NR]
  • gi|9758586|dbj|BAB09199.1| COP8 (constitutive photomorphogenic) homolog [Arabidopsis thaliana] [NCBI NR]
  • gi|55976535|sp|Q8L5U0.2|CSN4_ARATH RecName: Full=COP9 signalosome complex subunit 4; Short=Signalosome subunit 4; Short=AtS4; AltName: Full=Constitutive photomorphogenesis protein 8; AltName: Full=Protein FUSCA 4 [NCBI NR]
  • gi|51970862|dbj|BAD44123.1| COP8 (constitutive photomorphogenic) homolog [Arabidopsis thaliana] [NCBI NR]
  • gi|18056659|gb|AAL58103.1|AF395060_1 CSN complex subunit 4 [Arabidopsis thaliana] [NCBI NR]
  • gi|15239134|ref|NP_199111.1| COP8 (CONSTITUTIVE PHOTOMORPHOGENIC 8); protein binding [Arabidopsis thaliana] [NCBI NR]
  • COP9 signalosome complex subunit 4 OS=Arabidopsis thaliana GN=CSN4 PE=1 SV=2 [Swiss-Prot]
  • (Q9FMM1) COP8 (Constitutive photomorphogenic) homolog (CSN complex subunit 4) [athaliana3702.FASTAC.txt]
  • COP8 (constitutive photomorphogenic) homolog [Arabidopsis thaliana]gi|18056659|gb|AAL58103.1| CSN complex subunit 4 [Arabidopsis thaliana]gi|51970862|dbj|BAD44123.1| COP8 (constitutive photomorphogenic) homolog [Arabidopsis thaliana]gi|15239134|ref|NP_ [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 COP9 signalosome complex subunit 4 [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: FUS4, EMB134, COP14, CSN4, FUS8, COP8 | COP8 (CONSTITUTIVE PHOTOMORPHOGENIC 8) | chr5:17254698-17257877 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • At5g42970 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • COP8 (CONSTITUTIVE PHOTOMORPHOGENIC 8) [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • COP8 (constitutive photomorphogenic) homolog [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • COP9 signalosome complex subunit 4 (Signalosome subunit 4) (Constitutive photomorphogenesis protein 8) (FUSCA protein 4) (FUSCA4) (AtS4) [nr-271106-contam.fasta]
  • CSN complex subunit 4 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: COP8, FUS4, EMB134, COP14, CSN4, FUS8, ATS4 | Proteasome component (PCI) domain protein | chr5:17237470-17240649 REVERSE LENGTH=397 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 397 amino acids

    Gene Ontology:
    Cellular Component: signalosome [IDA][IPI][TAS]
    Biological Process: photomorphogenesis [TAS]
    G2 phase of mitotic cell cycle [IMP]
    cullin deneddylation [IMP]
    Molecular Function: protein binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDEALTNASA IGDQRQKIEQ YKLILSSVLS SNDLLQAQRF IDHILSDDVP LVVSRQLLQS  60
   61 FAQELGRLEP ETQKEIAQFT LTQIQPRVVS FEEQALVIRE KLAGLYESEQ EWSKAAQMLS 120
  121 GIDLDSGMRA VDDNFKLSKC IQIARLYLED DDAVNAEAFI NKASFLVSNS QNEVLNLQYK 180
  181 VCYARILDMK RKFLEAALRY YGISQIEQRQ IGDEEIDENA LEQALSAAVT CTILAGAGPQ 240
  241 RSRVLATLYK DERCSKLKIY PILQKVYLER ILRRPEIDAF SEELRPHQKA SLPDKSTVLD 300
  301 RAMIEHNLLS ASKLYTNIRF DELGTLLAID PRKAEKIAAN MIGQDRMRGS IDQEEAVIHF 360
  361 EDDVEELQQW DQQISGLCQA LNDILDGMAK KGMSVPV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..286] MSA 3.357994 View MSA. No confident structure predictions are available.
    2 View Details [287..397] PSI-BLAST 10.30103 Solution structure of the PCI domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  5.09178084244715 bayes_pls_golite062009
  • DNA binding
    		•  4.69269372393889 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.59221092058767 bayes_pls_golite062009
  • transcription factor activity
    		•  4.01234546864709 bayes_pls_golite062009
  • binding
    		•  3.52874320222492 bayes_pls_golite062009
  • transcription repressor activity
    		•  3.28015281691988 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.23304004014963 bayes_pls_golite062009
  • transcription activator activity
    		•  2.21230033124772 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.40206639526766 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  1.27763700765562 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  1.12147035668008 bayes_pls_golite062009
  • transcription factor binding
    		•  0.78051974537344 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  0.754042916649094 bayes_pls_golite062009
  • protein binding
    		•  0.753698599635855 bayes_pls_golite062009
  • specific transcriptional repressor activity
    		•  0.59003343009795 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  0.486434906547244 bayes_pls_golite062009
  • hydrolase activity
    		•  0.140191206949582 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle