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Protein Overview: UBP22_ARATH

General Information:
Name(s) found: UBP22_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|8979713|emb|CAB96834.1| ubiquitin specific protease-like protein [Arabidopsis thaliana] [NCBI NR]
  • gi|75263829|sp|Q9LEW0.1|UBP22_ARATH RecName: Full=Ubiquitin carboxyl-terminal hydrolase 22; AltName: Full=Ubiquitin thioesterase 22; AltName: Full=Ubiquitin-specific-processing protease 22; AltName: Full=Deubiquitinating enzyme 22; Short=AtUBP22 [NCBI NR]
  • gi|18416377|ref|NP_568239.1| UBP22 (UBIQUITIN-SPECIFIC PROTEASE 22); ubiquitin thiolesterase/ ubiquitin-specific protease/ zinc ion binding [Arabidopsis thaliana] [NCBI NR]
  • pir||T50788 ubiquitin specific proteinase homolog - Arabidopsis thaliana [NCBI NR]
  • Ubiquitin carboxyl-terminal hydrolase 22 OS=Arabidopsis thaliana GN=UBP22 PE=2 SV=1 [Swiss-Prot]
  • (Q9LEW0) Ubiquitin specific protease-like protein [athaliana3702.FASTAC.txt]
  • ubiquitin specific protease-like protein [Arabidopsis thaliana]gi|11358908|pir||T50788 ubiquitin specific proteinase homolog - Arabidopsis thalianagi|18416377|ref|NP_568239.1| ubiquitin-specific protease 22 (UBP22) [Arabidopsis thaliana] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Ubiquitin-specific protease 22 (UBP22) [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: UBP22 | UBP22 (UBIQUITIN-SPECIFIC PROTEASE 22); ubiquitin-specific protease | chr5:3410639-3412560 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • UBP22 (UBIQUITIN-SPECIFIC PROTEASE 22); cysteine-type endopeptidase/ ubiquitin thiolesterase/ ubiquitin-specific protease [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • ubiquitin specific protease-like protein [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: UBP22 | ubiquitin-specific protease 22 | chr5:3410638-3412559 FORWARD LENGTH=557 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 557 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: ubiquitin-dependent protein catabolic process [IEA]
    Molecular Function: ubiquitin-specific protease activity [ISS]
    zinc ion binding [IEA]
    ubiquitin thiolesterase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSARISFLKN PDPCNHLSDY KLRYGTDGYK SFNNLFRCFN DARIKIKLQG IDIPRCSYCS  60
   61 VYQKRLYICL ICRSISCSSH ILLHTQLNKG HDIAIDVERS ELYCCACIDQ VYDSEFDEVV 120
  121 VSKQLFGLGM SVKSGADVVA VRSNKKRRLD SQLIIGSNFL VSPRDRREKW TFPLGLRGLN 180
  181 NLGSTCFMNA VLQALVHAPP LRNFWLSGQH NRDLCPRRTM GLLCLPCDLD VIFSAMFSGD 240
  241 RTPYSPAHLL YSWWQHSTNL ATYEQQDSHE FFISLLDRIH ENEGKSKCLY QDNEECQCIT 300
  301 HKAFSGLLRS DVTCTTCGST STTYDPFIDI SLTLDSMNGF SPADCRKNRY SGGPSVNAIM 360
  361 PTLSGCLDFF TRSEKLGPDQ KLNCQSCGEK RESSKQMSIR RLPLLLCLHV KRFEHSLTRK 420
  421 TSRKIDSYLQ YPFRLNMSPY LSSSIIGKRF GNRIFAFDGE GEYDSSSSSS PSAEFEIFAV 480
  481 VTHKGMLESG HYVTYLRLKG LWYRCDDAWI NEVEEEVVRG CECYMLFYAQ ETVIQKAHKE 540
  541 LSYQVISMAD AFPFADC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..147] PSI-BLAST 9.0 No description for 2uzgA was found.
    2 View Details [148..557] PSI-BLAST 61.09691 No description for 2ibiA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ubiquitin-protein ligase activity
    		•  5.97121728620188 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  5.78935175140238 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  4.75377804653841 bayes_pls_golite062009
  • small conjugating protein-specific protease activity
    		•  3.4560986989594 bayes_pls_golite062009
  • ubiquitin-specific protease activity
    		•  3.40436079043913 bayes_pls_golite062009
  • binding
    		•  2.78710909602478 bayes_pls_golite062009
  • cysteine-type peptidase activity
    		•  2.7771990270637 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.72498741013971 bayes_pls_golite062009
  • protein binding
    		•  2.64803540957326 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  2.57382484274962 bayes_pls_golite062009
  • ubiquitin thiolesterase activity
    		•  2.27286633653932 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  2.11206038007886 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.01888784395048 bayes_pls_golite062009
  • DNA binding
    		•  2.00904221080834 bayes_pls_golite062009
  • transcription activator activity
    		•  1.45530270292081 bayes_pls_golite062009
  • transcription factor activity
    		•  1.22579085356684 bayes_pls_golite062009
  • transcription factor binding
    		•  1.11842175076436 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.926364718530146 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.90321253993065 bayes_pls_golite062009
  • ligase activity
    		•  0.63517530468004 bayes_pls_golite062009
  • thiolester hydrolase activity
    		•  0.600277034193586 bayes_pls_golite062009
  • hydrolase activity
    		•  0.52386813728704 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.350170315296021 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.255669498391574 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.233838999434784 bayes_pls_golite062009
  • catalytic activity
    		•  0.14112008370434 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.82

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle