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Protein Overview: CDPKC_ARATH

General Information:
Name(s) found: CDPKC_ARATH [Swiss-Prot]
Description(s) found:
Found 16 descriptions.
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  • Calcium-dependent protein kinase 12 OS=Arabidopsis thaliana GN=CPK12 PE=1 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 490 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: protein amino acid phosphorylation [IEA][ISS]
    Molecular Function: ATP binding [IEA]
    calcium ion binding [IEA]
    protein kinase activity [IEA]
    calmodulin-dependent protein kinase activity [ISS]
    protein serine/threonine kinase activity [IEA]
    kinase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANKPRTRWV LPYKTKNVED NYFLGQVLGQ GQFGTTFLCT HKQTGQKLAC KSIPKRKLLC  60
   61 QEDYDDVLRE IQIMHHLSEY PNVVRIESAY EDTKNVHLVM ELCEGGELFD RIVKRGHYSE 120
  121 REAAKLIKTI VGVVEACHSL GVVHRDLKPE NFLFSSSDED ASLKSTDFGL SVFCTPGEAF 180
  181 SELVGSAYYV APEVLHKHYG PECDVWSAGV ILYILLCGFP PFWAESEIGI FRKILQGKLE 240
  241 FEINPWPSIS ESAKDLIKKM LESNPKKRLT AHQVLCHPWI VDDKVAPDKP LDCAVVSRLK 300
  301 KFSAMNKLKK MALRVIAERL SEEEIGGLKE LFKMIDTDKS GTITFEELKD SMRRVGSELM 360
  361 ESEIQELLRA ADVDESGTID YGEFLAATIH LNKLEREENL VAAFSFFDKD ASGYITIEEL 420
  421 QQAWKEFGIN DSNLDEMIKD IDQDNDGQID YGEFVAMMRK GNGTGGGIGR RTMRNSLNFG 480
  481 TTLPDESMNV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..338] PSI-BLAST 70.69897 CALMODULIN-DEPENDENT PROTEIN KINASE FROM RAT
    2 View Details [339..490] PSI-BLAST 22.221849 Ca2+-regulatory region (CLD) from soybean calcium-dependent protein kinase-alpha (CDPK) in the presence of Ca2+ and the junction domain (JD)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphotransferase activity, alcohol group as acceptor
    		•  5.49988294224815 bayes_pls_golite062009
  • kinase activity
    		•  5.3287080791198 bayes_pls_golite062009
  • protein kinase activity
    		•  5.17195961442593 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  4.96052051118534 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  4.46381887831481 bayes_pls_golite062009
  • calmodulin-dependent protein kinase activity
    		•  4.31938467136214 bayes_pls_golite062009
  • transferase activity
    		•  3.97138602499442 bayes_pls_golite062009
  • binding
    		•  2.10874590528357 bayes_pls_golite062009
  • ATP binding
    		•  1.97600611746091 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  1.93596671856664 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  1.90928021591891 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.65732943334212 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.65726906484847 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.63763394711025 bayes_pls_golite062009
  • nucleotide binding
    		•  1.63195828048121 bayes_pls_golite062009
  • insulin receptor substrate binding
    		•  1.62657794525303 bayes_pls_golite062009
  • protein tyrosine kinase activity
    		•  1.3898059094397 bayes_pls_golite062009
  • receptor signaling protein serine/threonine kinase activity
    		•  1.38496328649031 bayes_pls_golite062009
  • receptor signaling protein activity
    		•  1.27291233344322 bayes_pls_golite062009
  • protein binding
    		•  1.22565748038754 bayes_pls_golite062009
  • catalytic activity
    		•  1.21655087018101 bayes_pls_golite062009
  • cyclin-dependent protein kinase activity
    		•  0.58590430118616 bayes_pls_golite062009
  • protein serine/threonine/tyrosine kinase activity
    		•  0.48345772948903 bayes_pls_golite062009
  • magnesium ion binding
    		•  0.393328812780268 bayes_pls_golite062009
  • MAP kinase kinase kinase activity
    		•  0.37115026509016 bayes_pls_golite062009
  • MAP kinase kinase activity
    		•  0.35402045013148 bayes_pls_golite062009
  • protein complex binding
    		•  0.343240719858581 bayes_pls_golite062009
  • signal transducer activity
    		•  0.270054246024761 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.270054246024761 bayes_pls_golite062009
  • MAP kinase activity
    		•  0.213371031328104 bayes_pls_golite062009
  • transmembrane receptor protein kinase activity
    		•  0.0556163711947139 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  0.00652065412910241 bayes_pls_golite062009
    2
    Term Confidence Notes
  • binding
    		•  2.53567454488695 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.51057181410195 bayes_pls_golite062009
  • kinase activity
    		•  1.48008348280256 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.34982153616582 bayes_pls_golite062009
  • cation binding
    		•  1.24254937475287 bayes_pls_golite062009
  • metal ion binding
    		•  1.24254937475287 bayes_pls_golite062009
  • ion binding
    		•  1.23493891392859 bayes_pls_golite062009
  • protein binding
    		•  1.16246005294206 bayes_pls_golite062009
  • transferase activity
    		•  1.00143834284844 bayes_pls_golite062009
  • structural molecule activity
    		•  0.048100972187449 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.78

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle