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Protein Overview: UBC1_ARATH

General Information:
Name(s) found: UBC1_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|7262682|gb|AAF43940.1|AC012188_17 Strong similarity to a Ubiquitin-conjugating Enzyme (E2-17 KD 1) from Arabidopsis thaliana gi|136636 and contains a Ubiqutin-conjugating Enzyme PF|00179 domain. ESTs gb|AA728508, gb|H36735, gb|AI100736 come from this [NCBI NR]
  • gi|66354398|gb|AAY44842.1| ubiquitinating enzyme [Arabidopsis thaliana] [NCBI NR]
  • gi|431260|gb|AAA32897.1| ubiquitin conjugating enzyme [NCBI NR]
  • gi|42571469|ref|NP_973825.1| UBC1 (UBIQUITIN CARRIER PROTEIN 1); ubiquitin-protein ligase [Arabidopsis thaliana] [NCBI NR]
  • gi|2981894|pdb|2AAK| Chain , Ubiquitin Conjugating Enzyme From Arabidopsis Thaliana [NCBI NR]
  • gi|21553917|gb|AAM63000.1| E2, ubiquitin-conjugating enzyme UBC1 [Arabidopsis thaliana] [NCBI NR]
  • gi|20259107|gb|AAM14269.1| putative ubiquitin-conjugating enzyme 1 (UBC1) [Arabidopsis thaliana] [NCBI NR]
  • gi|18394114|ref|NP_563951.1| UBC1 (UBIQUITIN CARRIER PROTEIN 1); ubiquitin-protein ligase [Arabidopsis thaliana] [NCBI NR]
  • gi|17979147|gb|AAL49769.1| putative E2, ubiquitin-conjugating enzyme UBC1 [Arabidopsis thaliana] [NCBI NR]
  • gi|166924|gb|AAA32903.1| ubiquitin carrier protein [NCBI NR]
  • gi|157834522|pdb|2AAK|A Chain A, Ubiquitin Conjugating Enzyme From Arabidopsis Thaliana [NCBI NR]
  • gi|136636|sp|P25865.1|UBC1_ARATH RecName: Full=Ubiquitin-conjugating enzyme E2 1; AltName: Full=Ubiquitin-conjugating enzyme E2-17 kDa 1; AltName: Full=Ubiquitin-protein ligase 1; AltName: Full=Ubiquitin carrier protein 1 [NCBI NR]
  • gi|12083310|gb|AAG48814.1|AF332451_1 putative E2, ubiquitin-conjugating enzyme 1 [Arabidopsis thaliana] [NCBI NR]
  • gi|110740882|dbj|BAE98537.1| hypothetical protein [Arabidopsis thaliana] [NCBI NR]
  • pir||S43781 ubiquitin-conjugating enzyme UBC1 - Arabidopsis thaliana [NCBI NR]
  • Ubiquitin-conjugating enzyme E2 1 OS=Arabidopsis thaliana GN=UBC1 PE=1 SV=1 [Swiss-Prot]
  • (P25865) Ubiquitin-conjugating enzyme E2-17 kDa 1 (EC 6.3.2.19) (Ubiquitin-protein ligase 1) (Ubiquitin carrier protein 1) [athaliana3702.FASTAC.txt]
  • E2, ubiquitin-conjugating enzyme UBC1 [Arabidopsis thaliana]gi|12083310|gb|AAG48814.1| putative E2, ubiquitin-conjugating enzyme 1 [Arabidopsis thaliana]gi|20259107|gb|AAM14269.1| putative ubiquitin-conjugating enzyme 1 (UBC1) [Arabidopsis thaliana]gi| [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Ubiquitin-conjugating enzyme E2-17 kDa 1 [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: ATUBC1, UBC1 | UBC1 (UBIQUITIN CARRIER PROTEIN 1); ubiquitin-protein ligase | chr1:4927289-4928131 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • hypothetical protein [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • ubiquitin conjugating enzyme [nr-271106-contam.fasta]
  • putative ubiquitin-conjugating enzyme 1 (UBC1) [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • E2, ubiquitin-conjugating enzyme UBC1 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • ubiquitinating enzyme [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • UBC1 (UBIQUITIN CARRIER PROTEIN 1); ubiquitin conjugating enzyme/ ubiquitin-like activating enzyme [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • putative E2, ubiquitin-conjugating enzyme 1 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • Chain , Ubiquitin Conjugating Enzyme From Arabidopsis Thaliana [nr-271106-contam.fasta]
  • Strong similarity to a Ubiquitin-conjugating Enzyme (E2-17 KD 1) from Arabidopsis thaliana gi|136636 and contains a Ubiqutin-conjugating Enzyme PF|00179 domain. ESTs gb|AA728508, gb|H36735, gb|AI100736 come from this gene [nr-271106-contam.fasta]
  • putative E2, ubiquitin-conjugating enzyme UBC1 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • ubiquitin carrier protein [nr-271106-contam.fasta]
  • Ubiquitin-conjugating enzyme E2-17 kDa 1 (Ubiquitin-protein ligase 1) (Ubiquitin carrier protein 1) [nr-271106-contam.fasta]
  • | Symbols: UBC1, ATUBC1 | ubiquitin carrier protein 1 | chr1:4927294-4928136 REVERSE LENGTH=152 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 152 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: vegetative to reproductive phase transition of meristem [IGI]
    negative regulation of flower development [IGI]
    leaf morphogenesis [IGI]
    ubiquitin-dependent protein catabolic process [IDA][TAS]
    histone H2B ubiquitination [IGI]
    Molecular Function: ubiquitin-protein ligase activity [IDA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTPARKRLM RDFKRLQQDP PAGISGAPQD NNIMLWNAVI FGPDDTPWDG GTFKLSLQFS  60
   61 EDYPNKPPTV RFVSRMFHPN IYADGSICLD ILQNQWSPIY DVAAILTSIQ SLLCDPNPNS 120
  121 PANSEAARMY SESKREYNRR VRDVVEQSWT AD

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Noble WS, et al. (2009) Manuscript in preparation. UBC1_ARATH gi|47169278, gi|...

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..152] PSI-BLAST 48.522879 UBIQUITIN CONJUGATING ENZYME FROM ARABIDOPSIS THALIANA

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ubiquitin-protein ligase activity
    		•  11.3486134076304 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  11.2964721480824 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  10.2401422444624 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  8.93602533934698 bayes_pls_golite062009
  • HLH domain binding
    		•  8.10904818707269 bayes_pls_golite062009
  • ligase activity
    		•  5.89730943108033 bayes_pls_golite062009
  • SUMO ligase activity
    		•  3.88357560284404 bayes_pls_golite062009
  • ISG15 ligase activity
    		•  3.37361650623694 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.21355731489173 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.13970605403492 bayes_pls_golite062009
  • DNA binding
    		•  1.95596447916631 bayes_pls_golite062009
  • protein binding
    		•  1.77678273247394 bayes_pls_golite062009
  • binding
    		•  1.75350658654805 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.5236035191291 bayes_pls_golite062009
  • transcription activator activity
    		•  1.19240180311941 bayes_pls_golite062009
  • catalytic activity
    		•  0.891402822028799 bayes_pls_golite062009
  • NEDD8 ligase activity
    		•  0.715654744941217 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.58835335751383 bayes_pls_golite062009
  • kinase activity
    		•  0.519703305315987 bayes_pls_golite062009
  • protein kinase activity
    		•  0.443948654247666 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.373779304908933 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.182854082413338 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.122859425935324 bayes_pls_golite062009
  • transferase activity
    		•  0.0984525836903841 bayes_pls_golite062009
  • transcription factor binding
    		•  0.0104967529560147 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle