Protein Overview: SYFA_ARATH

General Information:
Name(s) found:	SYFA_ARATH [Swiss-Prot]
Description(s) found: Found 15 descriptions. SHOW ALL	Phenylalanine--tRNA ligase alpha subunit, cytoplasmic OS=Arabidopsis thaliana GN=At4g39280 PE=2 SV=3 [Swiss-Prot]
Organism:	Arabidopsis thaliana
Length:	485 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IEA]
Biological Process:	tRNA aminoacylation for protein translation [IEA] phenylalanyl-tRNA aminoacylation [IEA][ISS] translation [IEA]
Molecular Function:	nucleotide binding [IEA] ATP binding [IEA][ISS] aminoacyl-tRNA ligase activity [IEA] phenylalanine-tRNA ligase activity [IEA][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEEAILGFL QNNEQITDSG QFSAEFNIDH NELVNVIKSL HGFRYIDVQD IKKETWILTD  60
   61 EGKKYAAEGS PEVQLFLAVP EEGSISKDEL QKKLAPAVFK IGCSQAGKNK WVEMGKQVSR 120
  121 KVKDVEDKVK GQLLQIQQGK EFDKESINSL KARKLIVPQI WKGYSVKKGP NYAPERKKVA 180
  181 TDLTRENLQN WKELEFKEYN FKAKGAPVDA GHLHALLKVR KQFKDIFVQM GFEEMPTNNY 240
  241 VESSFWNFDA LFQPQQHPAR DSHDTFFLKV PSTTRTLPED YVERVKRVHE SGGYGSRGYN 300
  301 YDWKREEANK NLLRTHTTAV SSRMLYALAQ KPFVPKKYFS IDRVFRNEAV DRTHLAEFHQ 360
  361 IEGLICDRGL TLGDLIGVLE DFFSRLGMSK LRFKPAYNPY TEPSMEIFSY HEGLGKWVEI 420
  421 GNSGMFRPEM LLPMGLPEDV RVIAWGLSLE RPTMILYGID NIRDLFGHKV DLDLIKRNPI 480
  481 CRIGI

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..109]	FFAS03	1.98	LysR-type regulatory protein CbnR
2	View Details	[110..485]	PSI-BLAST	74.69897	Phenyl-tRNA synthetase (PheRS) alpha subunit, PheS

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
transcription regulator activity	3.09413019441785	bayes_pls_golite062009
nucleic acid binding	2.8293727459515	bayes_pls_golite062009
DNA binding	2.66906990480864	bayes_pls_golite062009
binding	2.53822896550273	bayes_pls_golite062009
ligase activity	2.33035084655874	bayes_pls_golite062009
transcription factor activity	2.21460392371094	bayes_pls_golite062009
structural constituent of ribosome	0.764002516817766	bayes_pls_golite062009
structural molecule activity	0.756450227832198	bayes_pls_golite062009
sequence-specific DNA binding	0.665091289283954	bayes_pls_golite062009
protein binding	0.626618806841206	bayes_pls_golite062009
transcription activator activity	0.542530812773621	bayes_pls_golite062009
transcription repressor activity	0.423955395883599	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.0907538697485439	bayes_pls_golite062009

2

Term	Confidence	Notes
phenylalanine-tRNA ligase activity	13.8919118344182	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	12.5698315343202	bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds	12.5698315343202	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	12.5592545638101	bayes_pls_golite062009
ligase activity	6.92073480193262	bayes_pls_golite062009
glycine-tRNA ligase activity	2.61548498770105	bayes_pls_golite062009
threonine-tRNA ligase activity	2.18642354927	bayes_pls_golite062009
serine-tRNA ligase activity	2.07594942154162	bayes_pls_golite062009
catalytic activity	1.99372273395202	bayes_pls_golite062009
alanine-tRNA ligase activity	1.82594054955281	bayes_pls_golite062009
lysine-tRNA ligase activity	1.72324031407565	bayes_pls_golite062009
histidine-tRNA ligase activity	1.72215103383322	bayes_pls_golite062009
asparagine-tRNA ligase activity	0.921492123574877	bayes_pls_golite062009
binding	0.705666054154871	bayes_pls_golite062009
aspartate-tRNA ligase activity	0.00572514744734753	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle