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Protein Overview: PAB5_ARATH, PABP...

General Information:
Name(s) found: PABP5_ARATH [Swiss-Prot]
PAB5_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|7239504|gb|AAF43230.1|AC012654_14 Identical to the polyadenylate-binding protein 5 (PAB5) from Arabidopsis thaliana gb|M97657 [NCBI NR]
  • pir||B96740 hypothetical protein F14O23.15 [imported] - Arabidopsis thaliana [NCBI NR]
  • gi|21542448|sp|Q05196.2|PABP5_ARATH RecName: Full=Polyadenylate-binding protein 5; Short=Poly(A)-binding protein 5; Short=PABP 5 [NCBI NR]
  • gi|15217573|ref|NP_177322.1| PAB5 (POLY(A)-BINDING PROTEIN 5); RNA binding / poly(A) binding / translation initiation factor [Arabidopsis thaliana] [NCBI NR]
  • Polyadenylate-binding protein 5 OS=Arabidopsis thaliana GN=PAB5 PE=1 SV=2 [Swiss-Prot]
  • (Q05196) Polyadenylate-binding protein 5 (Poly(A)-binding protein 5) (PABP 5) [Swiss-Prot]
  • Identical to the polyadenylate-binding protein 5 (PAB5) from Arabidopsis thaliana gb|M97657gi|21542448|sp|Q05196|PAB5_ARATH Polyadenylate-binding protein 5 (Poly(A)-binding protein 5) (PABP 5)gi|15217573|ref|NP_177322.1| polyadenylate-binding protein 5 [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Polyadenylate-binding protein 5 [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: PAB5 | PAB5 (POLY(A)-BINDING PROTEIN); RNA binding | chr1:26994439-26997109 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • Polyadenylate-binding protein 5 (Poly(A)-binding protein 5) (PABP 5) [nr-271106-contam.fasta]
  • Identical to the polyadenylate-binding protein 5 (PAB5) from Arabidopsis thaliana gb|M97657 [nr-271106-contam.fasta]
  • PAB5 (POLY(A)-BINDING PROTEIN); RNA binding [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • PAB5 (POLY(A)-BINDING PROTEIN 5); RNA binding / poly(A) binding / translation initiation factor [Arabidopsis thaliana] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 668 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    cytosol [IDA]
    Biological Process: translational initiation [IGI]
    nuclear-transcribed mRNA poly(A) tail shortening [IGI]
    Molecular Function: translation initiation factor activity [ISS]
    RNA binding [ISS]
    poly(A) RNA binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVDQVIPNQP TVAAAAPPPF PAVSQVAAVA AAAAAAEALQ THPNSSLYVG DLDPSVNESH  60
   61 LLDLFNQVAP VHNLRVCRDL THRSLGYAYV NFANPEDASR AMESLNYAPI RDRPIRIMLS 120
  121 NRDPSTRLSG KGNVFIKNLD ASIDNKALYE TFSSFGTILS CKVAMDVVGR SKGYGFVQFE 180
  181 KEETAQAAID KLNGMLLNDK QVFVGHFVRR QDRARSESGA VPSFTNVYVK NLPKEITDDE 240
  241 LKKTFGKYGD ISSAVVMKDQ SGNSRSFGFV NFVSPEAAAV AVEKMNGISL GEDVLYVGRA 300
  301 QKKSDREEEL RRKFEQERIS RFEKLQGSNL YLKNLDDSVN DEKLKEMFSE YGNVTSCKVM 360
  361 MNSQGLSRGF GFVAYSNPEE ALLAMKEMNG KMIGRKPLYV ALAQRKEERQ AHLQSLFTQI 420
  421 RSPGTMSPVP SPMSGFHHHP PGGPMSGPHH PMFIGHNGQG LVPSQPMGYG YQVQFMPGMR 480
  481 PGAGPPNFMM PFPLQRQTQP GPRVGFRRGA NNMQQQFQQQ QMLQQNASRF MGGAGNRRNG 540
  541 MEASAPQGII PLPLNASANS HNAPQRSHKP TPLTISKLAS DLALASPDKH PRMLGDHLYP 600
  601 LVEQQEPANA AKVTGMLLEM DQAEILHLLE SPEALKAKVS EALDVLRRSA DPAAVSSVDD 660
  661 QFALSSSE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..219] PSI-BLAST 52.522879 Poly(A)-binding protein
    2 View Details [220..403] PSI-BLAST 15.0 Polypyrimidine tract-binding protein
    3 View Details [404..535] FFAS03 1.22 Crystal Structure of Rat Synapsin I C Domain Complexed to Ca.ATP
    4 View Details [536..668] PSI-BLAST 35.221849 poly(A) binding protein

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • RNA binding
    		•  6.73097473547076 bayes_pls_golite062009
    		• 6.62953239642182 bayes_pls_golite062009
  • mRNA binding
    		•  5.29759606920196 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.92126426323641 bayes_pls_golite062009
  • snRNA binding
    		•  4.06596327298973 bayes_pls_golite062009
  • binding
    		•  3.64400841800969 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  3.11990160533699 bayes_pls_golite062009
  • U1 snRNA binding
    		•  3.02511982045347 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  2.93798024346416 bayes_pls_golite062009
  • structural molecule activity
    		•  2.78501986457503 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.18211199677674 bayes_pls_golite062009
  • DNA binding
    		•  1.98418556946403 bayes_pls_golite062009
  • U2 snRNA binding
    		•  1.34078165372485 bayes_pls_golite062009
  • protein binding
    		•  1.12215421354121 bayes_pls_golite062009
  • transcription factor activity
    		•  1.07843408116687 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.06887262556449 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.824614388276642 bayes_pls_golite062009
  • eukaryotic initiation factor 4G binding
    		•  0.597542453741953 bayes_pls_golite062009
  • hydrolase activity
    		•  0.389390547875764 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.383589644462932 bayes_pls_golite062009
  • translation regulator activity
    		•  0.38120065819101 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.128616879457381 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  0.0459458211377304 bayes_pls_golite062009
    2
    Term Confidence Notes
  • RNA binding
    		•  6.73097473547076 bayes_pls_golite062009
    		• 6.62953239642182 bayes_pls_golite062009
  • mRNA binding
    		•  5.29759606920196 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.92126426323641 bayes_pls_golite062009
  • snRNA binding
    		•  4.06596327298973 bayes_pls_golite062009
  • binding
    		•  3.64400841800969 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  3.11990160533699 bayes_pls_golite062009
  • U1 snRNA binding
    		•  3.02511982045347 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  2.93798024346416 bayes_pls_golite062009
  • structural molecule activity
    		•  2.78501986457503 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.18211199677674 bayes_pls_golite062009
  • DNA binding
    		•  1.98418556946403 bayes_pls_golite062009
  • U2 snRNA binding
    		•  1.34078165372485 bayes_pls_golite062009
  • protein binding
    		•  1.12215421354121 bayes_pls_golite062009
  • transcription factor activity
    		•  1.07843408116687 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.06887262556449 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.824614388276642 bayes_pls_golite062009
  • eukaryotic initiation factor 4G binding
    		•  0.597542453741953 bayes_pls_golite062009
  • hydrolase activity
    		•  0.389390547875764 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.383589644462932 bayes_pls_golite062009
  • translation regulator activity
    		•  0.38120065819101 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.128616879457381 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  0.0459458211377304 bayes_pls_golite062009
    3 No functions predicted.
    4
    Term Confidence Notes
  • RNA binding
    		•  5.69788763665792 bayes_pls_golite062009
  • eukaryotic initiation factor 4G binding
    		•  5.42285329968544 bayes_pls_golite062009
  • mRNA binding
    		•  5.31297072316889 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  4.51056428709072 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.78909647605682 bayes_pls_golite062009
  • binding
    		•  2.76167454154417 bayes_pls_golite062009
  • poly(A) RNA binding
    		•  2.66269581586161 bayes_pls_golite062009
  • poly-purine tract binding
    		•  2.20136693536924 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  1.19350242454642 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  1.14692713780316 bayes_pls_golite062009
  • protein binding
    		•  0.856075580719879 bayes_pls_golite062009
  • ligase activity
    		•  0.38737123012383 bayes_pls_golite062009
  • catalytic activity
    		•  0.287695754348243 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  0.223805219849164 bayes_pls_golite062009
  • translation initiation factor binding
    		•  0.06484451210501 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.48

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle