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Protein Overview: METE1_ARATH

General Information:
Name(s) found: METE1_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|8134566|sp|O50008.1|METE_ARATH RecName: Full=5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; AltName: Full=Vitamin-B12-independent methionine synthase isozyme; AltName: Full=Cobalamin-independent methionine synthase isozyme [NCBI NR]
  • gi|2738248|gb|AAC50037.1| cobalamin-independent methionine synthase [Arabidopsis thaliana] [NCBI NR]
  • gi|20147149|gb|AAM10291.1| AT5g17920/MPI7_60 [Arabidopsis thaliana] [NCBI NR]
  • gi|17979547|gb|AAL50108.1| AT5g17920/MPI7_60 [Arabidopsis thaliana] [NCBI NR]
  • gi|17978930|gb|AAL47432.1| AT5g17920/MPI7_60 [Arabidopsis thaliana] [NCBI NR]
  • gi|15982785|gb|AAL09740.1| AT5g17920/MPI7_60 [Arabidopsis thaliana] [NCBI NR]
  • gi|15810169|gb|AAL06986.1| AT5g17920/MPI7_60 [Arabidopsis thaliana] [NCBI NR]
  • gi|15238686|ref|NP_197294.1| ATMS1; 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase/ copper ion binding / methionine synthase [Arabidopsis thaliana] [NCBI NR]
  • gi|15081618|gb|AAK82464.1| AT5g17920/MPI7_60 [Arabidopsis thaliana] [NCBI NR]
  • gi|145334507|ref|NP_001078599.1| ATMS1; 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase/ methionine synthase [Arabidopsis thaliana] [NCBI NR]
  • gi|13877643|gb|AAK43899.1|AF370522_1 cobalamin-independent methionine synthase [Arabidopsis thaliana] [NCBI NR]
  • gi|10177894|dbj|BAB11226.1| cobalamin-independent methionine synthase [Arabidopsis thaliana] [NCBI NR]
  • 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase OS=Arabidopsis thaliana GN=CIMS PE=1 SV=1 [Swiss-Prot]
  • 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 1 OS=Arabidopsis thaliana GN=MS1 PE=1 SV=1 [Swiss-Prot]
  • (O50008) 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) (Vitamin-B12-independent methionine synthase isozyme) (Cobalamin-independent methionine synthase isozyme) [athaliana3702.FASTAC.txt]
  • cobalamin-independent methionine synthase [Arabidopsis thaliana]gi|20147149|gb|AAM10291.1| AT5g17920/MPI7_60 [Arabidopsis thaliana]gi|17979547|gb|AAL50108.1| AT5g17920/MPI7_60 [Arabidopsis thaliana]gi|17978930|gb|AAL47432.1| AT5g17920/MPI7_60 [Arabidop [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: ATMETS, ATMS1, ATCIMS | ATCIMS (COBALAMIN-INDEPENDENT METHIONINE SYNTHASE); 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase/ methionine synthase | chr5:5935773-5939197 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • | Symbols: ATMETS, ATMS1, ATCIMS | ATCIMS (COBALAMIN-INDEPENDENT METHIONINE SYNTHASE) | chr5:5935773-5939197 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • AT5g17920/MPI7_60 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • cobalamin-independent methionine synthase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (Vitamin-B12-independent methionine synthase isozyme) (Cobalamin-independent methionine synthase isozyme) [nr-271106-contam.fasta]
  • ATCIMS (COBALAMIN-INDEPENDENT METHIONINE SYNTHASE); 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: ATCIMS, ATMETS, ATMS1 | Cobalamin-independent synthase family protein | chr5:5935771-5939195 FORWARD LENGTH=765 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
  • | Symbols: ATCIMS | Cobalamin-independent synthase family protein | chr5:5935771-5939195 FORWARD LENGTH=765 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 765 amino acids

    Gene Ontology:
    Cellular Component: chloroplast stroma [IDA]
    peroxisome [IDA]
    chloroplast [IDA]
    membrane [IDA]
    apoplast [IDA]
    cytosol [IDA][ISS]
    plasma membrane [IDA]
    Biological Process: methionine biosynthetic process [ISS]
    response to zinc ion [IEP]
    response to salt stress [IEP]
    response to cadmium ion [IEP]
    Molecular Function: methionine synthase activity [IDA]
    copper ion binding [IDA]
    5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASHIVGYPR MGPKRELKFA LESFWDGKST AEDLQKVSAD LRSSIWKQMS AAGTKFIPSN  60
   61 TFAHYDQVLD TTAMLGAVPP RYGYTGGEIG LDVYFSMARG NASVPAMEMT KWFDTNYHYI 120
  121 VPELGPEVNF SYASHKAVNE YKEAKALGVD TVPVLVGPVS YLLLSKAAKG VDKSFELLSL 180
  181 LPKILPIYKE VITELKAAGA TWIQLDEPVL VMDLEGQKLQ AFTGAYAELE STLSGLNVLV 240
  241 ETYFADIPAE AYKTLTSLKG VTAFGFDLVR GTKTLDLVKA GFPEGKYLFA GVVDGRNIWA 300
  301 NDFAASLSTL QALEGIVGKD KLVVSTSCSL LHTAVDLINE TKLDDEIKSW LAFAAQKVVE 360
  361 VNALAKALAG QKDEALFSAN AAALASRRSS PRVTNEGVQK AAAALKGSDH RRATNVSARL 420
  421 DAQQKKLNLP ILPTTTIGSF PQTVELRRVR REYKAKKVSE EDYVKAIKEE IKKVVDLQEE 480
  481 LDIDVLVHGE PERNDMVEYF GEQLSGFAFT ANGWVQSYGS RCVKPPVIYG DVSRPKAMTV 540
  541 FWSAMAQSMT SRPMKGMLTG PVTILNWSFV RNDQPRHETC YQIALAIKDE VEDLEKGGIG 600
  601 VIQIDEAALR EGLPLRKSEH AFYLDWAVHS FRITNCGVQD STQIHTHMCY SHFNDIIHSI 660
  661 IDMDADVITI ENSRSDEKLL SVFREGVKYG AGIGPGVYDI HSPRIPSSEE IADRVNKMLA 720
  721 VLEQNILWVN PDCGLKTRKY TEVKPALKNM VDAAKLIRSQ LASAK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..765] PSI-BLAST 1000.0 A. thaliana cobalamine independent methionine synthase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity
    		•  6.40786073037099 bayes_pls_golite062009
  • 5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity
    		•  6.40786073037099 bayes_pls_golite062009
  • uroporphyrinogen decarboxylase activity
    		•  3.13638443707338 bayes_pls_golite062009
  • S-methyltransferase activity
    		•  3.0142199413027 bayes_pls_golite062009
  • catalytic activity
    		•  2.37862248560593 bayes_pls_golite062009
  • binding
    		•  1.590130518929 bayes_pls_golite062009
  • carbon-carbon lyase activity
    		•  1.54242506764415 bayes_pls_golite062009
  • carboxy-lyase activity
    		•  1.52150758949987 bayes_pls_golite062009
  • lyase activity
    		•  0.825209465219608 bayes_pls_golite062009
  • protein binding
    		•  0.21865699924356 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle