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Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5-methyltetrahydropteroyltri-L-glutamate. Catalysis of the transfer of a methyl group to an acceptor molecule. Catalysis of the reaction: 5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = tetrahydropteroyltri-L-glutamate + L-methionine. Catalysis of the transfer of a methyl group to the sulfur atom of an acceptor molecule.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity
Acc: GO:0003871
Aspect: Molecular Function
Desc: Catalysis of the reaction: 5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = tetrahydropteroyltri-L-glutamate + L-methionine.
Synonyms:
  • homocysteine methylase activity
  • cobalamin-independent methionine synthase activity
  • methionine synthase (cobalamin-independent) activity
  • tetrahydropteroylglutamate-homocysteine transmethylase activity
  • tetrahydropteroyltriglutamate methyltransferase activity
  • methyltransferase, tetrahydropteroylglutamate-homocysteine transmethylase activity
  • MetE
  • 5-methyltetrahydropteroyltri-L-glutamate:L-homocysteine S-methyltransferase activity
  • methyltetrahydropteroylpolyglutamate:homocysteine methyltransferase activity
Proteins in PDR annotated with:
   This term: 14 [Search]
   Term or descendants: 14 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0003871 - 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity (interactive image map)
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