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Protein Overview: HXK2_ARATH

General Information:
Name(s) found: HXK2_ARATH [Swiss-Prot]
Description(s) found:
Found 15 descriptions.
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  • Hexokinase-2 OS=Arabidopsis thaliana GN=HXK2 PE=1 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 502 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDA][TAS]
    plastid [IDA]
    Biological Process: sugar mediated signaling pathway [IMP]
    hexokinase-dependent signaling [IMP]
    programmed cell death [IMP]
    Molecular Function: ATP binding [ISS]
    glucokinase activity [IDA]
    hexokinase activity [IMP][ISS]
    fructokinase activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKVAVATTV VCSVAVCAAA ALIVRRRMKS AGKWARVIEI LKAFEEDCAT PIAKLRQVAD  60
   61 AMTVEMHAGL ASEGGSKLKM LISYVDNLPS GDETGFFYAL DLGGTNFRVM RVLLGGKHDR 120
  121 VVKREFKEES IPPHLMTGKS HELFDFIVDV LAKFVATEGE DFHLPPGRQR ELGFTFSFPV 180
  181 KQLSLSSGTL INWTKGFSID DTVDKDVVGE LVKAMERVGL DMLVAALVND TIGTLAGGRY 240
  241 TNPDVVVAVI LGTGTNAAYV ERAHAIPKWH GLLPKSGEMV INMEWGNFRS SHLPLTEYDH 300
  301 SLDVDSLNPG EQILEKIISG MYLGEILRRV LLKMAEEAAF FGDIVPPKLK IPFIIRTPNM 360
  361 SAMHSDTSPD LKVVGSKLKD ILEVQTSSLK MRKVVISLCN IIASRGARLS AAGIYGILKK 420
  421 IGRDATKDGE AQKSVIAMDG GLFEHYTQFS ESMKSSLKEL LGDEVSESVE VILSNDGSGV 480
  481 GAALLAASHS QYLELEDDSE TS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..502] PSI-BLAST 168.0 Mammalian type I hexokinase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • kinase activity
    		•  2.81480196738665 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  2.66634930184926 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  2.47806699612578 bayes_pls_golite062009
  • structural molecule activity
    		•  2.37892721989886 bayes_pls_golite062009
  • carbohydrate kinase activity
    		•  2.33338276303563 bayes_pls_golite062009
  • binding
    		•  2.11855816699924 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.09111975841662 bayes_pls_golite062009
  • protein binding
    		•  2.00711904074672 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.84294882554466 bayes_pls_golite062009
  • hexokinase activity
    		•  1.70516840340504 bayes_pls_golite062009
  • DNA binding
    		•  1.70014394990425 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.69431775343358 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  1.58791290104307 bayes_pls_golite062009
  • glucose binding
    		•  1.58717365638543 bayes_pls_golite062009
  • transferase activity
    		•  1.58048472128722 bayes_pls_golite062009
  • transcription activator activity
    		•  1.35676801272576 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  1.30214785132007 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  1.30181101672725 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  1.27871475799533 bayes_pls_golite062009
  • myosin binding
    		•  1.26046360733002 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  1.18894708772738 bayes_pls_golite062009
  • transcription factor activity
    		•  1.06678984888387 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.908385694796738 bayes_pls_golite062009
  • mannokinase activity
    		•  0.766256764215041 bayes_pls_golite062009
  • actin binding
    		•  0.742062735414161 bayes_pls_golite062009
  • protein kinase activity
    		•  0.659672620542945 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.574998559133169 bayes_pls_golite062009
  • hydrolase activity
    		•  0.474893704700898 bayes_pls_golite062009
  • glucokinase activity
    		•  0.47468456642723 bayes_pls_golite062009
  • sugar binding
    		•  0.44352406324938 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.426216374317549 bayes_pls_golite062009
  • ATP binding
    		•  0.39408967688855 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.358452809509562 bayes_pls_golite062009
  • ATPase activity
    		•  0.338933039062396 bayes_pls_golite062009
  • catalytic activity
    		•  0.296484721581333 bayes_pls_golite062009
  • monosaccharide binding
    		•  0.20435276425198 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.173637392484485 bayes_pls_golite062009
  • nucleotide binding
    		•  0.168207023557983 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.104339549630743 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.101742118226005 bayes_pls_golite062009
  • chromatin binding
    		•  0.0489277194984092 bayes_pls_golite062009
  • unfolded protein binding
    		•  0.0304569608189402 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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