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View Structure Prediction Details

Protein: HXK2_ARATH
Organism: Arabidopsis thaliana
Length: 502 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HXK2_ARATH.

Description E-value Query
Range		 Subject
Range
gi|30961939 - gi|30961939|gb|AAP40021.1| hexokinase [Nicotiana benthamiana]
 716.0 [0..1] [497..1]

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Predicted Domain #1
Region A:
Residues: [1-502] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKVAVATTV VCSVAVCAAA ALIVRRRMKS AGKWARVIEI LKAFEEDCAT PIAKLRQVAD  60
   61 AMTVEMHAGL ASEGGSKLKM LISYVDNLPS GDETGFFYAL DLGGTNFRVM RVLLGGKHDR 120
  121 VVKREFKEES IPPHLMTGKS HELFDFIVDV LAKFVATEGE DFHLPPGRQR ELGFTFSFPV 180
  181 KQLSLSSGTL INWTKGFSID DTVDKDVVGE LVKAMERVGL DMLVAALVND TIGTLAGGRY 240
  241 TNPDVVVAVI LGTGTNAAYV ERAHAIPKWH GLLPKSGEMV INMEWGNFRS SHLPLTEYDH 300
  301 SLDVDSLNPG EQILEKIISG MYLGEILRRV LLKMAEEAAF FGDIVPPKLK IPFIIRTPNM 360
  361 SAMHSDTSPD LKVVGSKLKD ILEVQTSSLK MRKVVISLCN IIASRGARLS AAGIYGILKK 420
  421 IGRDATKDGE AQKSVIAMDG GLFEHYTQFS ESMKSSLKEL LGDEVSESVE VILSNDGSGV 480
  481 GAALLAASHS QYLELEDDSE TS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 168.0
Match: 1bg3A
Description: Mammalian type I hexokinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
kinase activity 2.81480196738665 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 2.66634930184926 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 2.47806699612578 bayes_pls_golite062009
structural molecule activity 2.37892721989886 bayes_pls_golite062009
carbohydrate kinase activity 2.33338276303563 bayes_pls_golite062009
binding 2.11855816699924 bayes_pls_golite062009
transcription regulator activity 2.09111975841662 bayes_pls_golite062009
protein binding 2.00711904074672 bayes_pls_golite062009
nucleic acid binding 1.84294882554466 bayes_pls_golite062009
hexokinase activity 1.70516840340504 bayes_pls_golite062009
DNA binding 1.70014394990425 bayes_pls_golite062009
cytoskeletal protein binding 1.69431775343358 bayes_pls_golite062009
structural constituent of cytoskeleton 1.58791290104307 bayes_pls_golite062009
glucose binding 1.58717365638543 bayes_pls_golite062009
transferase activity 1.58048472128722 bayes_pls_golite062009
transcription activator activity 1.35676801272576 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 1.30214785132007 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 1.30181101672725 bayes_pls_golite062009
pyrophosphatase activity 1.27871475799533 bayes_pls_golite062009
myosin binding 1.26046360733002 bayes_pls_golite062009
nucleoside-triphosphatase activity 1.18894708772738 bayes_pls_golite062009
transcription factor activity 1.06678984888387 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.908385694796738 bayes_pls_golite062009
mannokinase activity 0.766256764215041 bayes_pls_golite062009
actin binding 0.742062735414161 bayes_pls_golite062009
protein kinase activity 0.659672620542945 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.574998559133169 bayes_pls_golite062009
hydrolase activity 0.474893704700898 bayes_pls_golite062009
glucokinase activity 0.47468456642723 bayes_pls_golite062009
sugar binding 0.44352406324938 bayes_pls_golite062009
adenyl nucleotide binding 0.426216374317549 bayes_pls_golite062009
ATP binding 0.39408967688855 bayes_pls_golite062009
adenyl ribonucleotide binding 0.358452809509562 bayes_pls_golite062009
ATPase activity 0.338933039062396 bayes_pls_golite062009
catalytic activity 0.296484721581333 bayes_pls_golite062009
monosaccharide binding 0.20435276425198 bayes_pls_golite062009
purine nucleotide binding 0.173637392484485 bayes_pls_golite062009
nucleotide binding 0.168207023557983 bayes_pls_golite062009
ribonucleotide binding 0.104339549630743 bayes_pls_golite062009
purine ribonucleotide binding 0.101742118226005 bayes_pls_golite062009
chromatin binding 0.0489277194984092 bayes_pls_golite062009
unfolded protein binding 0.0304569608189402 bayes_pls_golite062009
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