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Protein Overview: CLCC_ARATH

General Information:
Name(s) found: CLCC_ARATH [Swiss-Prot]
Description(s) found:
Found 17 descriptions.
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  • Chloride channel protein CLC-c OS=Arabidopsis thaliana GN=CLC-C PE=1 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 779 amino acids

    Gene Ontology:
    Cellular Component: intracellular [TAS]
    plasma membrane [IDA]
    Biological Process: chloride transport [IEA][ISS]
    Molecular Function: anion channel activity [ISS]
    voltage-gated chloride channel activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDRHEGDHH DIEVEGGALH GFERKISGIL DDGSVGFRQP LLARNRKNTT SQIAIVGANT  60
   61 CPIESLDYEI FENDFFKQDW RSRKKIEILQ YTFLKWALAF LIGLATGLVG FLNNLGVENI 120
  121 AGFKLLLIGN LMLKEKYFQA FFAFAGCNLI LATAAASLCA FIAPAAAGSG IPEVKAYLNG 180
  181 IDAYSILAPS TLFVKIFGSI FGVAAGFVVG KEGPMVHTGA CIANLLGQGG SKKYRLTWKW 240
  241 LRFFKNDRDR RDLITCGAAA GVAAAFRAPV GGVLFALEEA ASWWRNALLW RTFFTTAVVA 300
  301 VVLRSLIEFC RSGRCGLFGK GGLIMFDVNS GPVLYSTPDL LAIVFLGVIG GVLGSLYNYL 360
  361 VDKVLRTYSI INEKGPRFKI MLVMAVSILS SCCAFGLPWL SQCTPCPIGI EEGKCPSVGR 420
  421 SSIYKSFQCP PNHYNDLSSL LLNTNDDAIR NLFTSRSENE FHISTLAIFF VAVYCLGIIT 480
  481 YGIAIPSGLF IPVILAGASY GRLVGRLLGP VSQLDVGLFS LLGAASFLGG TMRMTVSLCV 540
  541 ILLELTNNLL MLPLVMLVLL ISKTVADCFN RGVYDQIVTM KGLPYMEDHA EPYMRNLVAK 600
  601 DVVSGALISF SRVEKVGVIW QALKMTRHNG FPVIDEPPFT EASELCGIAL RSHLLVLLQG 660
  661 KKFSKQRTTF GSQILRSCKA RDFGKAGLGK GLKIEDLDLS EEEMEMYVDL HPITNTSPYT 720
  721 VLETLSLAKA AILFRQLGLR HLCVVPKTPG RPPIVGILTR HDFMPEHVLG LYPHIDPLK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..68] deduced N/A No confident structure predictions are available.
    2 View Details [69..545] PSI-BLAST 61.69897 Clc chloride channel
    3 View Details [546..779] PSI-BLAST 12.09691 Crystal structure of Inosine-5'-monophosphate dehydrogenase (TM1347) from THERMOTOGA MARITIMA at 2.18 A resolution

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • anion channel activity
    		•  6.77290758049983 bayes_pls_golite062009
  • chloride channel activity
    		•  6.77290758049983 bayes_pls_golite062009
  • anion transmembrane transporter activity
    		•  6.08111514985329 bayes_pls_golite062009
  • voltage-gated chloride channel activity
    		•  5.99544422864122 bayes_pls_golite062009
  • voltage-gated anion channel activity
    		•  5.99544422864122 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  5.07840957725271 bayes_pls_golite062009
  • ion channel activity
    		•  4.93164650815682 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  4.81149777353187 bayes_pls_golite062009
  • channel activity
    		•  4.78965126968592 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  4.78965126968592 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  4.67227438984104 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  4.27956097534048 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  4.255638017629 bayes_pls_golite062009
  • gated channel activity
    		•  4.1072949331811 bayes_pls_golite062009
  • transporter activity
    		•  2.94995161862691 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.84443650880263 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.82470397063503 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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