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View Structure Prediction Details

Protein: CLCC_ARATH
Organism: Arabidopsis thaliana
Length: 779 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CLCC_ARATH.

Description E-value Query
Range
Subject
Range
gi|21321022 - gi|21321022|dbj|BAB97267.1| chloride channel [Oryza sativa Japonica Group]
487.0 [0..11] [778..28]

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Predicted Domain #1
Region A:
Residues: [1-68]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDRHEGDHH DIEVEGGALH GFERKISGIL DDGSVGFRQP LLARNRKNTT SQIAIVGANT  60
   61 CPIESLDY

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [69-545]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EIFENDFFKQ DWRSRKKIEI LQYTFLKWAL AFLIGLATGL VGFLNNLGVE NIAGFKLLLI  60
   61 GNLMLKEKYF QAFFAFAGCN LILATAAASL CAFIAPAAAG SGIPEVKAYL NGIDAYSILA 120
  121 PSTLFVKIFG SIFGVAAGFV VGKEGPMVHT GACIANLLGQ GGSKKYRLTW KWLRFFKNDR 180
  181 DRRDLITCGA AAGVAAAFRA PVGGVLFALE EAASWWRNAL LWRTFFTTAV VAVVLRSLIE 240
  241 FCRSGRCGLF GKGGLIMFDV NSGPVLYSTP DLLAIVFLGV IGGVLGSLYN YLVDKVLRTY 300
  301 SIINEKGPRF KIMLVMAVSI LSSCCAFGLP WLSQCTPCPI GIEEGKCPSV GRSSIYKSFQ 360
  361 CPPNHYNDLS SLLLNTNDDA IRNLFTSRSE NEFHISTLAI FFVAVYCLGI ITYGIAIPSG 420
  421 LFIPVILAGA SYGRLVGRLL GPVSQLDVGL FSLLGAASFL GGTMRMTVSL CVILLEL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 61.69897
Match: 1kplA
Description: Clc chloride channel
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
anion channel activity 6.77290758049983 bayes_pls_golite062009
chloride channel activity 6.77290758049983 bayes_pls_golite062009
anion transmembrane transporter activity 6.08111514985329 bayes_pls_golite062009
voltage-gated chloride channel activity 5.99544422864122 bayes_pls_golite062009
voltage-gated anion channel activity 5.99544422864122 bayes_pls_golite062009
ion transmembrane transporter activity 5.07840957725271 bayes_pls_golite062009
ion channel activity 4.93164650815682 bayes_pls_golite062009
substrate-specific channel activity 4.81149777353187 bayes_pls_golite062009
channel activity 4.78965126968592 bayes_pls_golite062009
passive transmembrane transporter activity 4.78965126968592 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 4.67227438984104 bayes_pls_golite062009
voltage-gated ion channel activity 4.27956097534048 bayes_pls_golite062009
voltage-gated channel activity 4.255638017629 bayes_pls_golite062009
gated channel activity 4.1072949331811 bayes_pls_golite062009
transporter activity 2.94995161862691 bayes_pls_golite062009
transmembrane transporter activity 2.84443650880263 bayes_pls_golite062009
substrate-specific transporter activity 2.82470397063503 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [546-779]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TNNLLMLPLV MLVLLISKTV ADCFNRGVYD QIVTMKGLPY MEDHAEPYMR NLVAKDVVSG  60
   61 ALISFSRVEK VGVIWQALKM TRHNGFPVID EPPFTEASEL CGIALRSHLL VLLQGKKFSK 120
  121 QRTTFGSQIL RSCKARDFGK AGLGKGLKIE DLDLSEEEME MYVDLHPITN TSPYTVLETL 180
  181 SLAKAAILFR QLGLRHLCVV PKTPGRPPIV GILTRHDFMP EHVLGLYPHI DPLK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.09691
Match: 1vrdA
Description: Crystal structure of Inosine-5'-monophosphate dehydrogenase (TM1347) from THERMOTOGA MARITIMA at 2.18 A resolution
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle