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Protein Overview: CLCB_ARATH

General Information:
Name(s) found: CLCB_ARATH [Swiss-Prot]
Description(s) found:
Found 15 descriptions.
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  • Chloride channel protein CLC-b OS=Arabidopsis thaliana GN=CLC-B PE=1 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 780 amino acids

    Gene Ontology:
    Cellular Component: intracellular [TAS]
    Biological Process: chloride transport [IEA][ISS]
    Molecular Function: anion channel activity [ISS]
    voltage-gated chloride channel activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVEEDLNQIG GNSNYNGEGG DPESNTLNQP LVKANRTLSS TPLALVGAKV SHIESLDYEI  60
   61 NENDLFKHDW RKRSKAQVLQ YVFLKWTLAC LVGLFTGLIA TLINLAVENI AGYKLLAVGH 120
  121 FLTQERYVTG LMVLVGANLG LTLVASVLCV CFAPTAAGPG IPEIKAYLNG VDTPNMFGAT 180
  181 TMIVKIVGSI GAVAAGLDLG KEGPLVHIGS CIASLLGQGG TDNHRIKWRW LRYFNNDRDR 240
  241 RDLITCGSAA GVCAAFRSPV GGVLFALEEV ATWWRSALLW RTFFSTAVVV VVLREFIEIC 300
  301 NSGKCGLFGK GGLIMFDVSH VTYTYHVTDI IPVMLIGVIG GILGSLYNHL LHKVLRLYNL 360
  361 INEKGKIHKV LLSLTVSLFT SVCLYGLPFL AKCKPCDPSI DEICPTNGRS GNFKQFHCPK 420
  421 GYYNDLATLL LTTNDDAVRN LFSSNTPNEF GMGSLWIFFV LYCILGLFTF GIATPSGLFL 480
  481 PIILMGAAYG RMLGAAMGSY TSIDQGLYAV LGAAALMAGS MRMTVSLCVI FLELTNNLLL 540
  541 LPITMIVLLI AKTVGDSFNP SIYDIILHLK GLPFLEANPE PWMRNLTVGE LGDAKPPVVT 600
  601 LQGVEKVSNI VDVLKNTTHN AFPVLDEAEV PQVGLATGAT ELHGLILRAH LVKVLKKRWF 660
  661 LTEKRRTEEW EVREKFPWDE LAEREDNFDD VAITSAEMEM YVDLHPLTNT TPYTVMENMS 720
  721 VAKALVLFRQ VGLRHLLIVP KIQASGMCPV VGILTRQDLR AYNILQAFPL LEKSKGGKTH 780
  781

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..555] PSI-BLAST 59.09691 Clc chloride channel
    2 View Details [556..780] PSI-BLAST 9.69897 Inosine monophosphate dehydrogenase (IMPDH); Type II inosine monophosphate dehydrogenase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • anion channel activity
    		•  6.77290758049983 bayes_pls_golite062009
  • chloride channel activity
    		•  6.77290758049983 bayes_pls_golite062009
  • anion transmembrane transporter activity
    		•  6.08111514985329 bayes_pls_golite062009
  • voltage-gated chloride channel activity
    		•  5.99544422864122 bayes_pls_golite062009
  • voltage-gated anion channel activity
    		•  5.99544422864122 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  5.07840957725271 bayes_pls_golite062009
  • ion channel activity
    		•  4.93164650815682 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  4.81149777353187 bayes_pls_golite062009
  • channel activity
    		•  4.78965126968592 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  4.78965126968592 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  4.67227438984104 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  4.27956097534048 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  4.255638017629 bayes_pls_golite062009
  • gated channel activity
    		•  4.1072949331811 bayes_pls_golite062009
  • transporter activity
    		•  2.94995161862691 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.84443650880263 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.82470397063503 bayes_pls_golite062009
    2
    Term Confidence Notes
  • anion channel activity
    		•  4.72273788503492 bayes_pls_golite062009
  • chloride channel activity
    		•  4.72273788503492 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.33792188010109 bayes_pls_golite062009
  • anion transmembrane transporter activity
    		•  4.07884311796555 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.93353180499293 bayes_pls_golite062009
  • voltage-gated chloride channel activity
    		•  3.88653297495834 bayes_pls_golite062009
  • voltage-gated anion channel activity
    		•  3.88653297495834 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  3.3574064637316 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  3.18351510675711 bayes_pls_golite062009
  • ion channel activity
    		•  2.96289511581809 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  2.85393728592978 bayes_pls_golite062009
  • channel activity
    		•  2.83666655624333 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  2.83666655624333 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  2.73643550405923 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  2.26198818630559 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  2.23919445086891 bayes_pls_golite062009
  • transporter activity
    		•  2.21524357108065 bayes_pls_golite062009
  • gated channel activity
    		•  2.18781915118831 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.10896266379801 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.087339200694 bayes_pls_golite062009
  • di-, tri-valent inorganic cation transmembrane transporter activity
    		•  1.81809447487679 bayes_pls_golite062009
  • magnesium ion transmembrane transporter activity
    		•  1.02459848653197 bayes_pls_golite062009
  • binding
    		•  0.712468873233295 bayes_pls_golite062009
  • protein binding
    		•  0.069261088689358 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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