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Protein Overview: CE34935

General Information:
Name(s) found: CE34935 [WormBase]
Description(s) found:
Found 16 descriptions.
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  • WBGene00010784 locus:twk-48 status:Confirmed UniProt:Q7YWY7 protein_id:CAE17863.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 372 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEALink to PubMed article]
    integral to membrane [IEALink to PubMed article]
    Biological Process: potassium ion transport [IEALink to PubMed article]
    ion transport [IEALink to PubMed article]
    transmembrane transport [IEALink to PubMed article]
    Molecular Function: ion channel activity [IEALink to PubMed article]
    potassium channel activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGRRHRRSKV TRVVNLVKKI IAFFFSHIGL CALVVGYALL GAVIFKAVEG PHEAEIQELV  60
   61 KSAREKAVDV VWNATFRVNR LDSKQWKKTV LDEVKRFKTV CMLSIRKGYD GKEYGKQAQW 120
  121 TFTGAFLYSL TVITTIGYGN TAAKTYIGKT LTMLYAIIGI PLMLLFLTNI GDVMAKIFRF 180
  181 LYAQSIRLKF RLILWHKKRK AAKIRRANSL VSRLTRGHRV KADSSVDSFG LGAGADVEDL 240
  241 LTARVEMEQL EVRETAAAQL ESMTVPISLV VFTMLGYLGV GTTIFKVWEG WTFLESFYFC 300
  301 FISLTTIGFG DKFPSTSVSN TDEAQEKLVI TSIYLLFGMA LLAMCFNLAQ EEVQNKTRWI 360
  361 ADKFRSKEDD DD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..234] PSI-BLAST 25.522879 Mammalian Shaker Kv1.2 potassium channel- beta subunit complex
    2 View Details [235..372] PSI-BLAST 6.522879 Potassium channel-related protein MthK

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • potassium channel activity
    		•  6.80950139957332 bayes_pls_golite062009
  • voltage-gated potassium channel activity
    		•  6.78740036921969 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  6.69340621375858 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  6.55904318827964 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  6.55320598344395 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  5.06264960439093 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  4.86252983188139 bayes_pls_golite062009
  • cation channel activity
    		•  4.85749153259346 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.77144021609018 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  4.3961579058414 bayes_pls_golite062009
  • gated channel activity
    		•  4.19619757426613 bayes_pls_golite062009
  • inward rectifier potassium channel activity
    		•  4.13359972196575 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  4.09858664479122 bayes_pls_golite062009
  • ion channel activity
    		•  3.86720832958006 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  3.7587607940377 bayes_pls_golite062009
  • channel activity
    		•  3.7587607940377 bayes_pls_golite062009
  • transporter activity
    		•  2.93091397928047 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.82224868778929 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.54207434157938 bayes_pls_golite062009
  • ligand-gated channel activity
    		•  2.26062383880472 bayes_pls_golite062009
  • ligand-gated ion channel activity
    		•  2.26062383880472 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle