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Protein Overview: trs-1

General Information:
Name(s) found: trs-1 / CE33765 [WormBase]
Description(s) found:
Found 16 descriptions.
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  • WBGene00006617 locus:tars-1 status:Confirmed UniProt:Q86D21 protein_id:CAD89723.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 684 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEALink to PubMed article]
    Biological Process: tRNA aminoacylation for protein translation [IEALink to PubMed article]
    glycyl-tRNA aminoacylation [IEALink to PubMed article]
    histidyl-tRNA aminoacylation [IEALink to PubMed article]
    nematode larval development [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    proteolysis [IEALink to PubMed article]
    gamete generation [IMPLink to PubMed article]
    threonyl-tRNA aminoacylation [IEALink to PubMed article]
    prolyl-tRNA aminoacylation [IEALink to PubMed article]
    growth [IMPLink to PubMed articleLink to PubMed article]
    translation [IEALink to PubMed article]
    Molecular Function: nucleotide binding [IEALink to PubMed article]
    histidine-tRNA ligase activity [IEALink to PubMed article]
    ATP binding [IEALink to PubMed article]
    glycine-tRNA ligase activity [IEALink to PubMed article]
    aminoacyl-tRNA ligase activity [IEALink to PubMed article]
    proline-tRNA ligase activity [IEALink to PubMed article]
    threonine-tRNA ligase activity [IEALink to PubMed article]
    serine-type carboxypeptidase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKAPTDMAP WPAFIEERIK LWDKLKAEYD AEIAAKESEP IQITLPDGKI HEGKTWRTTP  60
   61 FEIAERISKG LAEAAVIAKV NGAVWDLDRP FEGNAKLELL KFDDDEAKQV FWHSSAHVLG 120
  121 EAMERYCGGH LCYGPPIQEG FYYDMWHENR TICPDDFPKI DQIVKAAVKD KQKFERLEMT 180
  181 KEDLLEMFKY NEFKVRIITE KIHTPKTTVY RCGPLIDLCR GPHVRHTGKV KAMAITKNSS 240
  241 SYWEGKADAE SLQRLYGISF PDSKQLKEWQ KLQEEAAKRD HRKLGKEHDL FFFHQLSPGS 300
  301 AFWYPKGAHI YNKLVDFIRK QYRRRGFTEV ITPNMYNKKL WETSGHWQHY SEDMFKIEVE 360
  361 KEEFGLKPMN CPGHCLMFGH MPHTYNELPF RFADFGVLHR NEMSGALTGL TRVRRFQQDD 420
  421 AHIFCRQDQI SEEIKQCLDF LEYAYEKVFG FTFKLNLSTR PEGFLGNIET WDKAEADLTN 480
  481 ALNASGRKWV LNPGDGAFYG PKIDITIQDA LKRNFQCATI QLDFQLPNQF DLSYFDEKGE 540
  541 KQRPVMIHRA VLGSVERMTA ILTESYGGKW PFWLSPRQCK IITVHESVRD YANDVKKQIF 600
  601 EAGFEIEYEE NCGDTMNKQV RKAQLAQFNF ILVIGAKEKE NGTVNVRTRD NAVRGEVALD 660
  661 KLISKFRRFA DEYVADTEKS EEWA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..684] PSI-BLAST 171.0 Threonyl-tRNA synthetase (ThrRS), C-terminal domain; Threonyl-tRNA synthetase (ThrRS), N-terminal 'additional' domain; Threonyl-tRNA synthetase (ThrRS), second 'additional' domain; Threonyl-tRNA synthetase (ThrRS)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  7.89468709683036 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  7.89468709683036 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  7.88410036819636 bayes_pls_golite062009
  • ligase activity
    		•  6.92073480193262 bayes_pls_golite062009
  • threonine-tRNA ligase activity
    		•  6.47381405106149 bayes_pls_golite062009
  • phenylalanine-tRNA ligase activity
    		•  2.99105702052936 bayes_pls_golite062009
  • serine-tRNA ligase activity
    		•  2.46505535069103 bayes_pls_golite062009
  • glycine-tRNA ligase activity
    		•  2.29229136935761 bayes_pls_golite062009
  • catalytic activity
    		•  1.99372273395202 bayes_pls_golite062009
  • alanine-tRNA ligase activity
    		•  1.82594054955281 bayes_pls_golite062009
  • lysine-tRNA ligase activity
    		•  1.72324031407565 bayes_pls_golite062009
  • histidine-tRNA ligase activity
    		•  1.72215103383322 bayes_pls_golite062009
  • binding
    		•  1.11470390774037 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.0753492604686 bayes_pls_golite062009
  • asparagine-tRNA ligase activity
    		•  0.921492123574877 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.897558352141977 bayes_pls_golite062009
  • DNA binding
    		•  0.854148126675211 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.55217603492525 bayes_pls_golite062009
  • transcription factor activity
    		•  0.283508546234551 bayes_pls_golite062009
  • aspartate-tRNA ligase activity
    		•  0.00572514744734753 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle