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View Structure Prediction Details

Protein: trs-1
Organism: Caenorhabditis elegans
Length: 684 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for trs-1.

Description E-value Query
Range
Subject
Range
gi|47575750, gi|... - gi|47575750|ref|NP_001001219.1| threonyl-tRNA synthetase-like 2 [Xenopus (Silurana) tropicalis], gi|...
628.0 [0..5] [681..42]

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Predicted Domain #1
Region A:
Residues: [1-684]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKAPTDMAP WPAFIEERIK LWDKLKAEYD AEIAAKESEP IQITLPDGKI HEGKTWRTTP  60
   61 FEIAERISKG LAEAAVIAKV NGAVWDLDRP FEGNAKLELL KFDDDEAKQV FWHSSAHVLG 120
  121 EAMERYCGGH LCYGPPIQEG FYYDMWHENR TICPDDFPKI DQIVKAAVKD KQKFERLEMT 180
  181 KEDLLEMFKY NEFKVRIITE KIHTPKTTVY RCGPLIDLCR GPHVRHTGKV KAMAITKNSS 240
  241 SYWEGKADAE SLQRLYGISF PDSKQLKEWQ KLQEEAAKRD HRKLGKEHDL FFFHQLSPGS 300
  301 AFWYPKGAHI YNKLVDFIRK QYRRRGFTEV ITPNMYNKKL WETSGHWQHY SEDMFKIEVE 360
  361 KEEFGLKPMN CPGHCLMFGH MPHTYNELPF RFADFGVLHR NEMSGALTGL TRVRRFQQDD 420
  421 AHIFCRQDQI SEEIKQCLDF LEYAYEKVFG FTFKLNLSTR PEGFLGNIET WDKAEADLTN 480
  481 ALNASGRKWV LNPGDGAFYG PKIDITIQDA LKRNFQCATI QLDFQLPNQF DLSYFDEKGE 540
  541 KQRPVMIHRA VLGSVERMTA ILTESYGGKW PFWLSPRQCK IITVHESVRD YANDVKKQIF 600
  601 EAGFEIEYEE NCGDTMNKQV RKAQLAQFNF ILVIGAKEKE NGTVNVRTRD NAVRGEVALD 660
  661 KLISKFRRFA DEYVADTEKS EEWA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 171.0
Match: 1qf6A
Description: Threonyl-tRNA synthetase (ThrRS), C-terminal domain; Threonyl-tRNA synthetase (ThrRS), N-terminal 'additional' domain; Threonyl-tRNA synthetase (ThrRS), second 'additional' domain; Threonyl-tRNA synthetase (ThrRS)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ligase activity, forming aminoacyl-tRNA and related compounds 7.89468709683036 bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds 7.89468709683036 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 7.88410036819636 bayes_pls_golite062009
ligase activity 6.92073480193262 bayes_pls_golite062009
threonine-tRNA ligase activity 6.47381405106149 bayes_pls_golite062009
phenylalanine-tRNA ligase activity 2.99105702052936 bayes_pls_golite062009
serine-tRNA ligase activity 2.46505535069103 bayes_pls_golite062009
glycine-tRNA ligase activity 2.29229136935761 bayes_pls_golite062009
catalytic activity 1.99372273395202 bayes_pls_golite062009
alanine-tRNA ligase activity 1.82594054955281 bayes_pls_golite062009
lysine-tRNA ligase activity 1.72324031407565 bayes_pls_golite062009
histidine-tRNA ligase activity 1.72215103383322 bayes_pls_golite062009
binding 1.11470390774037 bayes_pls_golite062009
transcription regulator activity 1.0753492604686 bayes_pls_golite062009
asparagine-tRNA ligase activity 0.921492123574877 bayes_pls_golite062009
nucleic acid binding 0.897558352141977 bayes_pls_golite062009
DNA binding 0.854148126675211 bayes_pls_golite062009
transcription repressor activity 0.55217603492525 bayes_pls_golite062009
transcription factor activity 0.283508546234551 bayes_pls_golite062009
aspartate-tRNA ligase activity 0.00572514744734753 bayes_pls_golite062009

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