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Protein Overview: mnat-1

General Information:
Name(s) found: mnat-1 / CE31957 [WormBase]
Description(s) found:
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  • WBGene00018769 locus:mnat-1 status:Confirmed UniProt:O17245 protein_id:CCD71696.1 [WormBase]
  • gi|32564565|ref|NP_494280.3| MNAT (menage a trois) TFIIH subunit family member (mnat-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|23820836|gb|AAB71017.3| Mnat (menage a trois) tfiih subunit protein 1 [Caenorhabditis elegans] [NCBI NR]
  • [wormpep88.fasta]
  • CE31957 WBGene00018769 locus:mnat-1 status:Confirmed TR:O17245 protein_id:AAB71017.3 [wormpep150.fasta]
  • 31957 WBGene00018769 status:Confirmed TR:O17245 protein_id:AAB71017.3 [wormpep130-phg-ecoli-orf-rand.fasta]
  • putative nuclear protein, with 2 coiled coil-4 domains, of eukaryotic origin (36.7 kD) (2C764) [Caenorhabditis elegans]gi|23820836|gb|AAB71017.3| Hypothetical protein F53G2.7 [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • CE31957 WBGene00018769 status:Confirmed TR:O17245 protein_id:AAB71017.3 [wormpep132.fasta]
  • 31957 WBGene00018769 locus:mnat-1 status:Confirmed TR:O17245 protein_id:AAB71017.3 [wormpep150-phg-orf-ecoli-rand.fasta]
  • status:Confirmed TR:O17245 protein_id:AAB71017.3 [wormpep115.fasta.reversed]
  • CE31957 WBGene00018769 locus:mnat-1 status:Confirmed UniProt:O17245_CAEEL protein_id:AAB71017.3 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE31957 WBGene00018769 locus:mnat-1 status:Confirmed UniProt:O17245_CAEEL protein_id:AAB71017.3| [wormORF-contam.fasta]
  • MNAT (menage a trois) TFIIH subunit family member (mnat-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Mnat (menage a trois) tfiih subunit protein 1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE31957 WBGene00018769 locus:mnat-1 status:Confirmed UniProt:O17245 protein_id:AAB71017.3 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE31957 WBGene00018769 locus:mnat-1 status:Confirmed UniProt:O17245 protein_id:CCD71696.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • MNAT (Menage a trois) TFIIH subunit OS=Caenorhabditis elegans GN=mnat-1 PE=1 SV=3 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 310 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed article]
    cell cycle [IEALink to PubMed article]
    reproduction [IMPLink to PubMed article]
    Molecular Function: zinc ion binding [IEALink to PubMed article]
    protein binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKECKKCKSN EYTNKQLVMM INECGHPLCK NCVDNIFALN SGNCHVCNRV LRKNNFREQI  60
   61 YEDPLIDKET FLRRKLRKIY NLKQDDFENL REFGDYQERF ETVVYNLVFE TNVNETNAEI 120
  121 QAFEEKHKEQ IDRNKRRLDD DQKWIEDQLR EERAMKARMT DHMEMDAKEQ EAASAVTDTR 180
  181 KIMDELRDSN VAAEVILDRE RKKQIEKELE EKEEQEKRKR RNKEMLQTRK RAAENMSFNT 240
  241 VIRVAGRAYV HQPLELVING PPMPNVSEIE ALGYLAHIRQ PTAEYIAGGY TPMLGCSRAL 300
  301 FEARIDLFSF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..63] PSI-BLAST 16.69897 TFIIH Mat1 subunit
    2 View Details [64..310] PSI-BLAST 4.39794 Heavy meromyosin subfragment

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • general RNA polymerase II transcription factor activity
    		•  6.51043144330453 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  3.14238164427954 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  3.12673603940339 bayes_pls_golite062009
  • binding
    		•  2.78710909602478 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.72498741013971 bayes_pls_golite062009
  • protein binding
    		•  2.64803540957326 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.32387297115017 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  2.10988747259202 bayes_pls_golite062009
  • DNA binding
    		•  2.00904221080834 bayes_pls_golite062009
  • transcription activator activity
    		•  1.45530270292081 bayes_pls_golite062009
  • transcription factor activity
    		•  1.22579085356684 bayes_pls_golite062009
  • transcription factor binding
    		•  1.11842175076436 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.926364718530146 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.90321253993065 bayes_pls_golite062009
  • hydrolase activity
    		•  0.52386813728704 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.350170315296021 bayes_pls_golite062009
  • ligase activity
    		•  0.34187399168736 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.255669498391574 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.233838999434784 bayes_pls_golite062009
  • catalytic activity
    		•  0.14112008370434 bayes_pls_golite062009
  • enzyme binding
    		•  0.104373352314595 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  0.024993043379745 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle