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View Structure Prediction Details

Protein: mnat-1
Organism: Caenorhabditis elegans
Length: 310 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mnat-1.

Description E-value Query
Range
Subject
Range
gi|61371458, gi|... - gi|61371458|gb|AAX43671.1| menage a trois 1 [synthetic construct], gi|61371451|gb|AAX43670.1| menage...
219.0 [0..2] [309..4]

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Predicted Domain #1
Region A:
Residues: [1-63]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKECKKCKSN EYTNKQLVMM INECGHPLCK NCVDNIFALN SGNCHVCNRV LRKNNFREQI  60
   61 YED

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.69897
Match: 1g25A
Description: TFIIH Mat1 subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
general RNA polymerase II transcription factor activity 6.51043144330453 bayes_pls_golite062009
small conjugating protein ligase activity 3.14238164427954 bayes_pls_golite062009
ubiquitin-protein ligase activity 3.12673603940339 bayes_pls_golite062009
binding 2.78710909602478 bayes_pls_golite062009
transcription regulator activity 2.72498741013971 bayes_pls_golite062009
protein binding 2.64803540957326 bayes_pls_golite062009
nucleic acid binding 2.32387297115017 bayes_pls_golite062009
acid-amino acid ligase activity 2.10988747259202 bayes_pls_golite062009
DNA binding 2.00904221080834 bayes_pls_golite062009
transcription activator activity 1.45530270292081 bayes_pls_golite062009
transcription factor activity 1.22579085356684 bayes_pls_golite062009
transcription factor binding 1.11842175076436 bayes_pls_golite062009
sequence-specific DNA binding 0.926364718530146 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.90321253993065 bayes_pls_golite062009
hydrolase activity 0.52386813728704 bayes_pls_golite062009
transcription repressor activity 0.350170315296021 bayes_pls_golite062009
ligase activity 0.34187399168736 bayes_pls_golite062009
transcription coactivator activity 0.255669498391574 bayes_pls_golite062009
transcription cofactor activity 0.233838999434784 bayes_pls_golite062009
catalytic activity 0.14112008370434 bayes_pls_golite062009
enzyme binding 0.104373352314595 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 0.024993043379745 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [64-310]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLIDKETFLR RKLRKIYNLK QDDFENLREF GDYQERFETV VYNLVFETNV NETNAEIQAF  60
   61 EEKHKEQIDR NKRRLDDDQK WIEDQLREER AMKARMTDHM EMDAKEQEAA SAVTDTRKIM 120
  121 DELRDSNVAA EVILDRERKK QIEKELEEKE EQEKRKRRNK EMLQTRKRAA ENMSFNTVIR 180
  181 VAGRAYVHQP LELVINGPPM PNVSEIEALG YLAHIRQPTA EYIAGGYTPM LGCSRALFEA 240
  241 RIDLFSF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.39794
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle