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Protein Overview: dli-1

General Information:
Name(s) found: dli-1 / CE30893 [WormBase]
Description(s) found:
Found 17 descriptions.
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  • WBGene00001007 locus:dli-1 status:Confirmed UniProt:G5ECK7 protein_id:CAC42262.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 441 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: negative regulation of vulval development [IMPLink to PubMed article]
    pronuclear migration [IMPLink to PubMed article]
    hermaphrodite genitalia development [IMPLink to PubMed articleLink to PubMed article]
    locomotory behavior [IMPLink to PubMed article]
    morphogenesis of an epithelium [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    Molecular Function: motor activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPPTAQPLEF DDTANAVLPV LYSSTDEEVG IWRELLASKK TNTNQGSTVI VLGDNRSGKS  60
   61 SLLSRLDKSD RTVKPKSLLG YRVLHVQNDA RDASYAYQLG TAGANLNPSE LLQIPVWSLD 120
  121 GNAACASLLK HALPATPAEA IFILTASIDN PNLIHSLKRW ANVCTEQAQK HFTKEDLKAG 180
  181 RSQQEKMWQE YVDPVQSQMS TSVVGSFADE HNLLPLDQGT LTENCGVTFM VVITKSDLGK 240
  241 EFTDAQFAKI SIQLRKFCLS LGATLVFTSA KETKNIQLLQ KYIVHRSFGT AFTSAAQVIE 300
  301 RESIFVPAGW DGEKKIDIIR ESIPDVDSAL EPTRDKLRPV AKEQLIEAEE DQAFLKKLMD 360
  361 ILATSTTTAA PKPRTMQEEP TDKDSPLANF FSNLLNKDKP SKVSSPSTVS QPMDAAATQA 420
  421 QLDRLLKSAQ SPKPQPRDSD A

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-1 hcp1 IP from december2004 Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..239] PSI-BLAST 46.221849 Structure of doubly prenylated Ypt1:GDI complex
    2 View Details [240..441] Pfam 16.585027 No description for PF05783.2 was found. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • microtubule motor activity
    		•  7.68336791348661 bayes_pls_golite062009
  • motor activity
    		•  4.04927796049806 bayes_pls_golite062009
  • plus-end-directed microtubule motor activity
    		•  3.89478272344579 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  2.9316157348091 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.85508132376901 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  2.83578652703908 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  2.83259287122192 bayes_pls_golite062009
  • tubulin binding
    		•  2.67743463093593 bayes_pls_golite062009
  • microtubule binding
    		•  2.59155206524122 bayes_pls_golite062009
  • transporter activity
    		•  2.54024930442614 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.4101693596493 bayes_pls_golite062009
  • ATPase activity
    		•  2.3671333448422 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.35987232569028 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  2.15516086601295 bayes_pls_golite062009
  • binding
    		•  2.01755875920323 bayes_pls_golite062009
  • actin binding
    		•  1.75397031486306 bayes_pls_golite062009
  • hydrolase activity
    		•  1.55579437761895 bayes_pls_golite062009
  • microfilament motor activity
    		•  1.28029120876672 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.26618119830599 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.912853112793192 bayes_pls_golite062009
  • nucleotide binding
    		•  0.905342574142397 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.904115761720541 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.904053997411779 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.877711904204486 bayes_pls_golite062009
  • actin filament binding
    		•  0.728264616959762 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.403546959736573 bayes_pls_golite062009
  • ATP binding
    		•  0.38929752840764 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.364108656344062 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.356069365520539 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.328995639437459 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.264741960233164 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.252628307425696 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.191104435852081 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.190037546554641 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.189653398557061 bayes_pls_golite062009
  • GTPase activity
    		•  0.105546189348878 bayes_pls_golite062009
  • protein binding
    		•  0.071010918255742 bayes_pls_golite062009
  • minus-end-directed microtubule motor activity
    		•  0.068779631341469 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.0111338193708552 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle