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View Structure Prediction Details

Protein: dli-1
Organism: Caenorhabditis elegans
Length: 441 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dli-1.

Description E-value Query
Range
Subject
Range
DC1L2_MOUSE - Cytoplasmic dynein 1 light intermediate chain 2 OS=Mus musculus GN=Dync1li2 PE=1 SV=2
375.0 [0..1] [441..1]

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Predicted Domain #1
Region A:
Residues: [1-239]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPPTAQPLEF DDTANAVLPV LYSSTDEEVG IWRELLASKK TNTNQGSTVI VLGDNRSGKS  60
   61 SLLSRLDKSD RTVKPKSLLG YRVLHVQNDA RDASYAYQLG TAGANLNPSE LLQIPVWSLD 120
  121 GNAACASLLK HALPATPAEA IFILTASIDN PNLIHSLKRW ANVCTEQAQK HFTKEDLKAG 180
  181 RSQQEKMWQE YVDPVQSQMS TSVVGSFADE HNLLPLDQGT LTENCGVTFM VVITKSDLG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.221849
Match: 2bcgY
Description: Structure of doubly prenylated Ypt1:GDI complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
microtubule motor activity 7.68336791348661 bayes_pls_golite062009
motor activity 4.04927796049806 bayes_pls_golite062009
plus-end-directed microtubule motor activity 3.89478272344579 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.9316157348091 bayes_pls_golite062009
pyrophosphatase activity 2.85508132376901 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.83578652703908 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.83259287122192 bayes_pls_golite062009
tubulin binding 2.67743463093593 bayes_pls_golite062009
microtubule binding 2.59155206524122 bayes_pls_golite062009
transporter activity 2.54024930442614 bayes_pls_golite062009
cytoskeletal protein binding 2.4101693596493 bayes_pls_golite062009
ATPase activity 2.3671333448422 bayes_pls_golite062009
transmembrane transporter activity 2.35987232569028 bayes_pls_golite062009
ATPase activity, coupled 2.15516086601295 bayes_pls_golite062009
binding 2.01755875920323 bayes_pls_golite062009
actin binding 1.75397031486306 bayes_pls_golite062009
hydrolase activity 1.55579437761895 bayes_pls_golite062009
microfilament motor activity 1.28029120876672 bayes_pls_golite062009
substrate-specific transporter activity 1.26618119830599 bayes_pls_golite062009
purine nucleotide binding 0.912853112793192 bayes_pls_golite062009
nucleotide binding 0.905342574142397 bayes_pls_golite062009
purine ribonucleotide binding 0.904115761720541 bayes_pls_golite062009
ribonucleotide binding 0.904053997411779 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.877711904204486 bayes_pls_golite062009
actin filament binding 0.728264616959762 bayes_pls_golite062009
active transmembrane transporter activity 0.403546959736573 bayes_pls_golite062009
ATP binding 0.38929752840764 bayes_pls_golite062009
adenyl ribonucleotide binding 0.364108656344062 bayes_pls_golite062009
adenyl nucleotide binding 0.356069365520539 bayes_pls_golite062009
ion transmembrane transporter activity 0.328995639437459 bayes_pls_golite062009
primary active transmembrane transporter activity 0.264741960233164 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 0.252628307425696 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0.191104435852081 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 0.190037546554641 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 0.189653398557061 bayes_pls_golite062009
GTPase activity 0.105546189348878 bayes_pls_golite062009
protein binding 0.071010918255742 bayes_pls_golite062009
minus-end-directed microtubule motor activity 0.068779631341469 bayes_pls_golite062009
structural constituent of cytoskeleton 0.0111338193708552 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [240-441]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KEFTDAQFAK ISIQLRKFCL SLGATLVFTS AKETKNIQLL QKYIVHRSFG TAFTSAAQVI  60
   61 ERESIFVPAG WDGEKKIDII RESIPDVDSA LEPTRDKLRP VAKEQLIEAE EDQAFLKKLM 120
  121 DILATSTTTA APKPRTMQEE PTDKDSPLAN FFSNLLNKDK PSKVSSPSTV SQPMDAAATQ 180
  181 AQLDRLLKSA QSPKPQPRDS DA

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 16.585027
Match: PF05783.2
Description: No description for PF05783.2 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle