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Protein Overview: pif-1

General Information:
Name(s) found: pif-1 / CE30311 [WormBase]
Description(s) found:
Found 21 descriptions.
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  • WBGene00004028 locus:pif-1 status:Confirmed UniProt:G5EFV7 protein_id:CCD73407.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 677 amino acids

    Gene Ontology:
    Cellular Component: exodeoxyribonuclease V complex [IEALink to PubMed article]
    Biological Process: NONE FOUND
    Molecular Function: nucleotide binding [IEALink to PubMed article]
    nucleoside-triphosphatase activity [IEALink to PubMed article]
    exodeoxyribonuclease V activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKSLQTDEN GGVSESPSNC TYCYTLECSL RIESTSSIKK KTPISSKSAI MTVGRNAQRK  60
   61 IHLQIELKTT ATGQPAVVCY DVTDAVVHLQ SVANGKCTVE IPSLSLMFQM FNCAPRKLNV 120
  121 FMKSLQAKLD IMKMEKSPIS AVPRQFSRPP AVFSVLSPLT ISEMRKVKKL REPSALARPS 180
  181 KEATTPKRRT SSMNLLAGGL ENRIMNRSIG LKRTTSFARD DREKAETLVS LKSFKDAPAI 240
  241 SERIQLSDEQ KSVVRCVINS RTSVFFTGSA GTGKSVILRR IIEMLPAGNT YITAATGVAA 300
  301 SQIGGITLHA FCGFRYENST PEQCLKQVLR QNHMVRQWKQ CSHLIIDEIS MIDRDFFEAL 360
  361 EYVARTVRNN DKPFGGIQLI ITGDFFQLPP VSKDEPVFCF ESEAWSRCIQ KTIVLKNVKR 420
  421 QNDNVFVKIL NNVRVGKCDF KSADILKESS KNQFPSSVIP TKLCTHSDDA DRINSSSIET 480
  481 TQGDAKTFHA YDDESFDTHA KARTLAQKKL VLKVGAQVML IKNIDVIKGL CNGSRGFVEK 540
  541 FSENGNPMIR FVSQADASIE IRRSKFSVRI PGSDAPLIRR QLPLQLAWAI SIHKSQGMTL 600
  601 DCAEISLERV FADGQAYVAL SRARSLAAIR IIGFDASCVR ANSKVIDFYK SIEAECDDEQ 660
  661 DWEAPAAGPR LKRVRSI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..113] PSI-BLAST 3.522879 Crystal Structure Analysis of ClpB
    2 View Details [114..677] PSI-BLAST 46.0 RecBCD:DNA complex

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • telomeric DNA binding
    		•  4.27839338838273 bayes_pls_golite062009
  • single-stranded telomeric DNA binding
    		•  2.76169895887092 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  2.72462789867829 bayes_pls_golite062009
  • double-stranded telomeric DNA binding
    		•  2.66745455858981 bayes_pls_golite062009
  • binding
    		•  2.64537357529343 bayes_pls_golite062009
  • DNA helicase activity
    		•  2.2817164193758 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.21184938313192 bayes_pls_golite062009
  • DNA binding
    		•  1.94055378599526 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  1.88455339138556 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  1.84050240798436 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.83584389083042 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  1.81138802583782 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  1.78927528875848 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  1.78903889318615 bayes_pls_golite062009
  • helicase activity
    		•  1.70242731830224 bayes_pls_golite062009
  • deoxyribonuclease activity
    		•  1.66853770005159 bayes_pls_golite062009
  • protein-DNA loading ATPase activity
    		•  1.29640539057136 bayes_pls_golite062009
  • hydrolase activity
    		•  1.29419296935491 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  1.19311444180077 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  1.19311444180077 bayes_pls_golite062009
  • ATPase activity
    		•  1.18431260772292 bayes_pls_golite062009
  • DNA-directed DNA polymerase activity
    		•  1.17617511072239 bayes_pls_golite062009
  • motor activity
    		•  1.14667913749579 bayes_pls_golite062009
  • DNA polymerase activity
    		•  1.14104131900023 bayes_pls_golite062009
  • DNA clamp loader activity
    		•  1.12431517057397 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.782430219754236 bayes_pls_golite062009
  • transcription factor activity
    		•  0.697256579145077 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.6071273686445 bayes_pls_golite062009
  • microtubule motor activity
    		•  0.60036517876321 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.500462538667228 bayes_pls_golite062009
  • DEAD/H-box RNA helicase binding
    		•  0.498523632581808 bayes_pls_golite062009
  • protein binding
    		•  0.170837278876362 bayes_pls_golite062009
  • nucleotide binding
    		•  0.114848452385726 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.10713474095071 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.0916519414118148 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.0915913646217636 bayes_pls_golite062009
  • 3'-5' DNA helicase activity
    		•  0.0769112340058804 bayes_pls_golite062009
  • actin binding
    		•  0.00482938540552702 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.86

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle