Protein Overview: cle-1

General Information:
Name(s) found:	cle-1 / CE29706 [WormBase]
Description(s) found: Found 21 descriptions. SHOW ALL	WBGene00000527 locus:cle-1 status:Confirmed UniProt:G5EDV5 protein_id:CAD21700.1 [WormBase]
Organism:	Caenorhabditis elegans
Length:	778 amino acids
Gene Ontology:
Cellular Component:	basement membrane [IDA] cytoplasm [IEA] cell junction [IDA] extracellular matrix [IEA]
Biological Process:	hermaphrodite genitalia development [IMP] phosphate transport [IEA] cell adhesion [IEA]
Molecular Function:	structural molecule activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLPRHHLGG LLYFCALYLL RASQAQPPTF FALNALPGDS ETEVDLLAPV KASLNADARV  60
   61 FRAKGIESLP AIGLQRGVEI AVPYRLYLPR NFFKQFSLLA TIKPMDKRGG YLFAAVNAYD 120
  121 SAVDIGLLIE PAGTKQTNIS LIVRSVAIVS FLVEDFSQQW TQFALEVVDQ TVTFYFKCRR 180
  181 FASRQVTSLP DFSFDEAEKL YIASAGPIID NGFEGAIQEL KLIDDATQGS RQCDEQWGAE 240
  241 GSGTPEEFKK TQESSELQKI SDFPPTPAPP PPYPTPQLAP HDLRSYEQQA ATTPFQGAPP 300
  301 SNQCTQVCRG EPGPQGPSGN DGIPGSHGAP GHQGERGADG APGLHGSRGD QGLPGPPGMP 360
  361 GLAGPPGPPG SGTGHGSGAD GPQGPPGLPG APGRDGTSGV EGQRGPQGPP GPKGDDGVSM 420
  421 ESLTDDDIER IARRVASIQK ESNEPMRGDL PEYNSKVHSF TTKGEKGERG APGAPGAPAP 480
  481 PAYGTLTTGT AVNVHATTVE LFASARSTSV GQLAFATSSQ QLFIRVTNGW KEIQLTHFHP 540
  541 FVETRHSTQN SRQNDASHAG RSRTGSAAAP WYPKANLDEP QRDAGVHNKD RVIHMIALSQ 600
  601 PFSGNLHGLR GADLQCYREA RAAGYTTTFR AMLSSNVQDL VRIVHSVDFD TTVVNVAGHH 660
  661 LFPSWRSFVN GAQMNPHAKL FSFDRHDVLN DSRWPDKRVW HGSKDGGIRA EQYCDGWRRA 720
  721 DSSLTSLAGH ISSNTSIFQS SGSEKCENKL VVLCVENMSK YHGDRILRLH RITSDFKK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

New Feature: Upload Your Own Microscopy Data

No microscopy data found in the PDR for this protein.

Protein Structure Data

[What does the above image mean?]
[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..143]	PSI-BLAST	42.045757	No description for 2uurA was found.
2	View Details	[144..609]	PSI-BLAST	49.0	No description for 1y0fA was found.
3	View Details	[610..778]	PSI-BLAST	87.522879	Endostatin

Functions predicted (by domain):

#

Gene Ontology predictions

1

No functions predicted.

2

Term	Confidence	Notes
extracellular matrix structural constituent	5.79011844700146	bayes_pls_golite062009
glycosaminoglycan binding	3.99293323211329	bayes_pls_golite062009
polysaccharide binding	3.62081068500275	bayes_pls_golite062009
carbohydrate binding	2.85222848359059	bayes_pls_golite062009
binding	2.67440026099196	bayes_pls_golite062009
pattern binding	2.08318151477871	bayes_pls_golite062009
growth factor activity	2.0453811346021	bayes_pls_golite062009
receptor binding	2.00166772827156	bayes_pls_golite062009
protein binding	1.92861594281923	bayes_pls_golite062009
extracellular matrix structural constituent conferring tensile strength	1.85149712995845	bayes_pls_golite062009
heparin binding	1.57698350443806	bayes_pls_golite062009
hyaluronic acid binding	1.55173574394091	bayes_pls_golite062009
sugar binding	0.968405226037797	bayes_pls_golite062009
receptor activity	0.427193670352265	bayes_pls_golite062009
cell surface binding	0.157511560978157	bayes_pls_golite062009
transmembrane receptor activity	0.0794028045607619	bayes_pls_golite062009
mannose binding	0.0513743237055473	bayes_pls_golite062009

3

Term	Confidence	Notes
extracellular matrix structural constituent	5.79011844700146	bayes_pls_golite062009
glycosaminoglycan binding	3.99293323211329	bayes_pls_golite062009
polysaccharide binding	3.62081068500275	bayes_pls_golite062009
carbohydrate binding	2.85222848359059	bayes_pls_golite062009
binding	2.67440026099196	bayes_pls_golite062009
pattern binding	2.08318151477871	bayes_pls_golite062009
growth factor activity	2.0453811346021	bayes_pls_golite062009
receptor binding	2.00166772827156	bayes_pls_golite062009
protein binding	1.92861594281923	bayes_pls_golite062009
extracellular matrix structural constituent conferring tensile strength	1.85149712995845	bayes_pls_golite062009
heparin binding	1.57698350443806	bayes_pls_golite062009
hyaluronic acid binding	1.55173574394091	bayes_pls_golite062009
sugar binding	0.968405226037797	bayes_pls_golite062009
receptor activity	0.427193670352265	bayes_pls_golite062009
cell surface binding	0.157511560978157	bayes_pls_golite062009
transmembrane receptor activity	0.0794028045607619	bayes_pls_golite062009
mannose binding	0.0513743237055473	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

Philius confidence legend

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle