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View Structure Prediction Details

Protein: cle-1
Organism: Caenorhabditis elegans
Length: 778 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cle-1.

Description E-value Query
Range		 Subject
Range
cle-1 - cle-1 isoform A status:Partially_confirmed UniProt:Q7JL30 protein_id:CAD21701.2
 564.0 [0..34] [778..394]

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Predicted Domain #1
Region A:
Residues: [1-143] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLPRHHLGG LLYFCALYLL RASQAQPPTF FALNALPGDS ETEVDLLAPV KASLNADARV  60
   61 FRAKGIESLP AIGLQRGVEI AVPYRLYLPR NFFKQFSLLA TIKPMDKRGG YLFAAVNAYD 120
  121 SAVDIGLLIE PAGTKQTNIS LIV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.045757
Match: 2uurA
Description: No description for 2uurA was found.

Predicted Domain #2
Region A:
Residues: [144-609] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSVAIVSFLV EDFSQQWTQF ALEVVDQTVT FYFKCRRFAS RQVTSLPDFS FDEAEKLYIA  60
   61 SAGPIIDNGF EGAIQELKLI DDATQGSRQC DEQWGAEGSG TPEEFKKTQE SSELQKISDF 120
  121 PPTPAPPPPY PTPQLAPHDL RSYEQQAATT PFQGAPPSNQ CTQVCRGEPG PQGPSGNDGI 180
  181 PGSHGAPGHQ GERGADGAPG LHGSRGDQGL PGPPGMPGLA GPPGPPGSGT GHGSGADGPQ 240
  241 GPPGLPGAPG RDGTSGVEGQ RGPQGPPGPK GDDGVSMESL TDDDIERIAR RVASIQKESN 300
  301 EPMRGDLPEY NSKVHSFTTK GEKGERGAPG APGAPAPPAY GTLTTGTAVN VHATTVELFA 360
  361 SARSTSVGQL AFATSSQQLF IRVTNGWKEI QLTHFHPFVE TRHSTQNSRQ NDASHAGRSR 420
  421 TGSAAAPWYP KANLDEPQRD AGVHNKDRVI HMIALSQPFS GNLHGL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 49.0
Match: 1y0fA
Description: No description for 1y0fA was found.

Predicted functions:

Term Confidence Notes
extracellular matrix structural constituent 5.79011844700146 bayes_pls_golite062009
glycosaminoglycan binding 3.99293323211329 bayes_pls_golite062009
polysaccharide binding 3.62081068500275 bayes_pls_golite062009
carbohydrate binding 2.85222848359059 bayes_pls_golite062009
binding 2.67440026099196 bayes_pls_golite062009
pattern binding 2.08318151477871 bayes_pls_golite062009
growth factor activity 2.0453811346021 bayes_pls_golite062009
receptor binding 2.00166772827156 bayes_pls_golite062009
protein binding 1.92861594281923 bayes_pls_golite062009
extracellular matrix structural constituent conferring tensile strength 1.85149712995845 bayes_pls_golite062009
heparin binding 1.57698350443806 bayes_pls_golite062009
hyaluronic acid binding 1.55173574394091 bayes_pls_golite062009
sugar binding 0.968405226037797 bayes_pls_golite062009
receptor activity 0.427193670352265 bayes_pls_golite062009
cell surface binding 0.157511560978157 bayes_pls_golite062009
transmembrane receptor activity 0.0794028045607619 bayes_pls_golite062009
mannose binding 0.0513743237055473 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [610-778] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RGADLQCYRE ARAAGYTTTF RAMLSSNVQD LVRIVHSVDF DTTVVNVAGH HLFPSWRSFV  60
   61 NGAQMNPHAK LFSFDRHDVL NDSRWPDKRV WHGSKDGGIR AEQYCDGWRR ADSSLTSLAG 120
  121 HISSNTSIFQ SSGSEKCENK LVVLCVENMS KYHGDRILRL HRITSDFKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 87.522879
Match: 1dy0A
Description: Endostatin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
extracellular matrix structural constituent 5.79011844700146 bayes_pls_golite062009
glycosaminoglycan binding 3.99293323211329 bayes_pls_golite062009
polysaccharide binding 3.62081068500275 bayes_pls_golite062009
carbohydrate binding 2.85222848359059 bayes_pls_golite062009
binding 2.67440026099196 bayes_pls_golite062009
pattern binding 2.08318151477871 bayes_pls_golite062009
growth factor activity 2.0453811346021 bayes_pls_golite062009
receptor binding 2.00166772827156 bayes_pls_golite062009
protein binding 1.92861594281923 bayes_pls_golite062009
extracellular matrix structural constituent conferring tensile strength 1.85149712995845 bayes_pls_golite062009
heparin binding 1.57698350443806 bayes_pls_golite062009
hyaluronic acid binding 1.55173574394091 bayes_pls_golite062009
sugar binding 0.968405226037797 bayes_pls_golite062009
receptor activity 0.427193670352265 bayes_pls_golite062009
cell surface binding 0.157511560978157 bayes_pls_golite062009
transmembrane receptor activity 0.0794028045607619 bayes_pls_golite062009
mannose binding 0.0513743237055473 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle