Protein Overview: ari-1

General Information:
Name(s) found:	ari-1 / CE29680 [WormBase]
Description(s) found: Found 19 descriptions. SHOW ALL	WBGene00016158 locus:ari-1 status:Confirmed UniProt:O01965 protein_id:CCD61206.1 [WormBase]
Organism:	Caenorhabditis elegans
Length:	494 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	zinc ion binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSDDEINMD DSDSSQGEID DGCMSDDDGI VLESREQNSS DYKDNGEPDN EVLNHDSLEA  60
   61 EMKKTITDVQ AVLQVKTGVC RILLHKYKWN KESLLERFYE HPDTTTFLID AHVIPRRQER 120
  121 LPAGDAECDI CCSLGELSGL SCNHRACTQC WKAYLTNKIA NNAQSEIECM APNCKLLIED 180
  181 EKVMFYITDP TVIATYRKLI VASYVETNRL LKWCPGIDCG KAVRVSHWEP RLVVCSCGSR 240
  241 FCFSCGHDWH EPVNCRLLKL WLKKCNDDSE TSNWINANTK ECPKCMITIE KDGGCNHMTC 300
  301 KNTACRFEFC WMCLGPWEPH GSSWYSCNRF DDSAAKNARD AQEVSRANLQ RYLFYYNRYM 360
  361 GHQQSLRLEG KLYATVKSKM EQMQTLSMSW IEVQFLRKAV DVLSECRRTL MFTYAFAFYL 420
  421 KRDNNAIIFE SNQKDLEMET EQLSGFLERD LDNENLVTLK QKVQDKYRYV EHRRKVLLDH 480
  481 CSEGADQELW VFNE

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..112]	MSA	1.251991	View MSA. No confident structure predictions are available.
2	View Details	[113..208]	PSI-BLAST	4.221849	No description for 2egpA was found.
3	View Details	[209..282]	FFAS03	3.16	Solution Structure of the IBR domain of the RING finger protein 31 protein
4	View Details	[283..329]	PSI-BLAST	8.69897	Solution Structure of the C-terminal RING from a RING-IBR-RING (TRIAD) motif
5	View Details	[330..494]	MSA	5.48199	View MSA. No confident structure predictions are available.

Functions predicted (by domain):

#

Gene Ontology predictions

1

No functions predicted.

2

No functions predicted.

3

Term	Confidence	Notes
ubiquitin-protein ligase activity	5.25982737281228	bayes_pls_golite062009
small conjugating protein ligase activity	5.16068345159314	bayes_pls_golite062009
acid-amino acid ligase activity	4.24782814163304	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	2.79292110382407	bayes_pls_golite062009
binding	2.11628925728357	bayes_pls_golite062009
protein binding	1.50887080730571	bayes_pls_golite062009
small conjugating protein-specific protease activity	1.02238152139385	bayes_pls_golite062009
ubiquitin-specific protease activity	0.821040441472875	bayes_pls_golite062009
nucleic acid binding	0.69956438716198	bayes_pls_golite062009
transcription regulator activity	0.522112597101813	bayes_pls_golite062009
ligase activity	0.424146907469434	bayes_pls_golite062009
cysteine-type peptidase activity	0.356312424125648	bayes_pls_golite062009
DNA binding	0.231306651563916	bayes_pls_golite062009
hydrolase activity	0.185228576891116	bayes_pls_golite062009
catalytic activity	0.168711389690753	bayes_pls_golite062009
peptidase activity	0.107857202210184	bayes_pls_golite062009
ubiquitin thiolesterase activity	0.0136579100966835	bayes_pls_golite062009

4

Term	Confidence	Notes
ubiquitin-protein ligase activity	5.65442784325159	bayes_pls_golite062009
small conjugating protein ligase activity	5.55686022186257	bayes_pls_golite062009
acid-amino acid ligase activity	4.59153177011595	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	3.07217714843839	bayes_pls_golite062009
binding	2.19426901055464	bayes_pls_golite062009
protein binding	1.62051249360163	bayes_pls_golite062009
small conjugating protein-specific protease activity	1.2126425713931	bayes_pls_golite062009
ubiquitin-specific protease activity	1.03469202541773	bayes_pls_golite062009
nucleic acid binding	0.708499177773075	bayes_pls_golite062009
ligase activity	0.63517530468004	bayes_pls_golite062009
transcription regulator activity	0.553991532499653	bayes_pls_golite062009
cysteine-type peptidase activity	0.50197530717959	bayes_pls_golite062009
ubiquitin thiolesterase activity	0.265769062717221	bayes_pls_golite062009
DNA binding	0.227671243150662	bayes_pls_golite062009
hydrolase activity	0.156835837705934	bayes_pls_golite062009
catalytic activity	0.14112008370434	bayes_pls_golite062009
peptidase activity	0.121357659741468	bayes_pls_golite062009

5

No functions predicted.

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle