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Protein Overview: CE28417

General Information:
Name(s) found: CE28417 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00020649 locus:sma-10 status:Confirmed UniProt:H2L0D4 protein_id:CCD72527.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 737 amino acids

    Gene Ontology:
    Cellular Component: extracellular region [IEALink to PubMed article]
    Biological Process: regulation of cell growth [IEALink to PubMed article]
    gamete generation [IMPLink to PubMed article]
    positive regulation of multicellular organism growth [IMPLink to PubMed article]
    Molecular Function: protein binding [IEALink to PubMed article]
    insulin-like growth factor binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIVYSLLLLI LYDFLPKVVT FDTVCIGLCH CVGNVVDCSS LDLSEIPTTI PNNTRILLLS  60
   61 DNEIESIDKS RLKGFYFLQT LDISNNIIRH IDFEFFYNLP NLKILNIRKN RLARIPRGSH 120
  121 ELGHLEKLDL RSNLISTVTS EELSYLAAVR SVDLSRNLIS YLPKPTTSAK VNIEKLDLAS 180
  181 NSITDIGTDH FSSFNTLVTL KLARNHITTL NQFSFSRLRK LESLDLTRNM IREVRFLAFN 240
  241 QLPSLQNVSL ARNDVYRLDD GMFYACEGLK HLNLSTNRVQ AVTEGWMFGL TSLEVLDLSY 300
  301 NQIQSFHISS WSHTPKLKWL SLHSNRIQSL PSGSFRVLRQ LEELILSANS IDSLHKFALV 360
  361 GMSSLHKLDL SSNTLAVCVE DGAVLYNTSM PFLRSLRFTN NQLRVIPKRA FERFPALEEL 420
  421 DLTDNPIATI HPEAFEPLEL KRLVMNSSSI LCDCQISWLA SWIYRLKLDK SSIIAKCSYP 480
  481 PPLADLYVVA IDTANLTCHN DSPRAKIVRQ PVEVSTLIGE KARFTCNVYG ASPLSIEWRV 540
  541 MENGQPRVLV QDSATFLSIN RTAVVNGTFD ERELAAAELL LDNVAMTDNS EYQCVARNRF 600
  601 GSDFSTHVKL QVYQAPKFTY TPEDMPLLVG QTAKFLCAAT GTPRPEIKWA FEQIPFPAAE 660
  661 ARRLYVTPND DHIYIMNVTK EDQGAYTCHA TNVAGQTQAS ANLIVFELIY CSNSLSFTCL 720
  721 FSQTQVFRKL LPLPRKP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..619] PSI-BLAST 53.522879 The molecular structure of toll-like receptor 3 ligand binding domain
    2 View Details [620..737] PSI-BLAST 14.522879 Crystal Structure of the Ig 1-2-3 fragment of NCAM

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • receptor activity
    		•  4.00123250685257 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  3.81769911097805 bayes_pls_golite062009
  • binding
    		•  3.17641566810715 bayes_pls_golite062009
  • molecular transducer activity
    		•  3.10913345555941 bayes_pls_golite062009
  • signal transducer activity
    		•  3.10913345555941 bayes_pls_golite062009
  • extracellular matrix structural constituent
    		•  2.79767000113033 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.13338563453164 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.09812904791121 bayes_pls_golite062009
  • receptor binding
    		•  1.97970998659961 bayes_pls_golite062009
  • DNA binding
    		•  1.94748821300258 bayes_pls_golite062009
  • olfactory receptor activity
    		•  1.79502606732682 bayes_pls_golite062009
  • fibroblast growth factor 1 binding
    		•  1.68957060156689 bayes_pls_golite062009
  • antigen binding
    		•  1.45942243170397 bayes_pls_golite062009
  • cell adhesion molecule binding
    		•  1.36789541796983 bayes_pls_golite062009
  • transmembrane receptor protein kinase activity
    		•  1.30657787244536 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.23901105851653 bayes_pls_golite062009
  • growth factor binding
    		•  1.21242049144353 bayes_pls_golite062009
  • transcription factor activity
    		•  1.19760118797575 bayes_pls_golite062009
  • protein binding
    		•  1.17809977833322 bayes_pls_golite062009
  • transmembrane receptor protein tyrosine kinase activity
    		•  1.08793833350628 bayes_pls_golite062009
  • platelet-derived growth factor receptor binding
    		•  1.04423921087796 bayes_pls_golite062009
  • peptide antigen binding
    		•  1.03871842737922 bayes_pls_golite062009
  • G-protein coupled receptor activity
    		•  1.02428106476324 bayes_pls_golite062009
  • fibroblast growth factor binding
    		•  0.940492274094239 bayes_pls_golite062009
  • fibroblast growth factor receptor activity
    		•  0.83975918695548 bayes_pls_golite062009
  • protein complex binding
    		•  0.83543827718565 bayes_pls_golite062009
  • peptide binding
    		•  0.729048089532569 bayes_pls_golite062009
  • integrin binding
    		•  0.599569390248921 bayes_pls_golite062009
  • protein kinase activity
    		•  0.274138794214258 bayes_pls_golite062009
  • carbohydrate binding
    		•  0.0389714345254086 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.71

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle