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View Structure Prediction Details

Protein: CE28417
Organism: Caenorhabditis elegans
Length: 737 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE28417.

Description E-value Query
Range
Subject
Range
gi|76658979 - gi|76658979|ref|XP_583040.2| PREDICTED: similar to leucine-rich repeats and immunoglobulin-like doma...
419.0 [0..20] [736..223]

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Predicted Domain #1
Region A:
Residues: [1-619]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIVYSLLLLI LYDFLPKVVT FDTVCIGLCH CVGNVVDCSS LDLSEIPTTI PNNTRILLLS  60
   61 DNEIESIDKS RLKGFYFLQT LDISNNIIRH IDFEFFYNLP NLKILNIRKN RLARIPRGSH 120
  121 ELGHLEKLDL RSNLISTVTS EELSYLAAVR SVDLSRNLIS YLPKPTTSAK VNIEKLDLAS 180
  181 NSITDIGTDH FSSFNTLVTL KLARNHITTL NQFSFSRLRK LESLDLTRNM IREVRFLAFN 240
  241 QLPSLQNVSL ARNDVYRLDD GMFYACEGLK HLNLSTNRVQ AVTEGWMFGL TSLEVLDLSY 300
  301 NQIQSFHISS WSHTPKLKWL SLHSNRIQSL PSGSFRVLRQ LEELILSANS IDSLHKFALV 360
  361 GMSSLHKLDL SSNTLAVCVE DGAVLYNTSM PFLRSLRFTN NQLRVIPKRA FERFPALEEL 420
  421 DLTDNPIATI HPEAFEPLEL KRLVMNSSSI LCDCQISWLA SWIYRLKLDK SSIIAKCSYP 480
  481 PPLADLYVVA IDTANLTCHN DSPRAKIVRQ PVEVSTLIGE KARFTCNVYG ASPLSIEWRV 540
  541 MENGQPRVLV QDSATFLSIN RTAVVNGTFD ERELAAAELL LDNVAMTDNS EYQCVARNRF 600
  601 GSDFSTHVKL QVYQAPKFT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.522879
Match: 2a0zA
Description: The molecular structure of toll-like receptor 3 ligand binding domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [620-737]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YTPEDMPLLV GQTAKFLCAA TGTPRPEIKW AFEQIPFPAA EARRLYVTPN DDHIYIMNVT  60
   61 KEDQGAYTCH ATNVAGQTQA SANLIVFELI YCSNSLSFTC LFSQTQVFRK LLPLPRKP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.522879
Match: 1qz1A
Description: Crystal Structure of the Ig 1-2-3 fragment of NCAM
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
receptor activity 4.00123250685257 bayes_pls_golite062009
transmembrane receptor activity 3.81769911097805 bayes_pls_golite062009
binding 3.17641566810715 bayes_pls_golite062009
molecular transducer activity 3.10913345555941 bayes_pls_golite062009
signal transducer activity 3.10913345555941 bayes_pls_golite062009
extracellular matrix structural constituent 2.79767000113033 bayes_pls_golite062009
nucleic acid binding 2.13338563453164 bayes_pls_golite062009
transcription regulator activity 2.09812904791121 bayes_pls_golite062009
receptor binding 1.97970998659961 bayes_pls_golite062009
DNA binding 1.94748821300258 bayes_pls_golite062009
olfactory receptor activity 1.79502606732682 bayes_pls_golite062009
fibroblast growth factor 1 binding 1.68957060156689 bayes_pls_golite062009
antigen binding 1.45942243170397 bayes_pls_golite062009
cell adhesion molecule binding 1.36789541796983 bayes_pls_golite062009
transmembrane receptor protein kinase activity 1.30657787244536 bayes_pls_golite062009
transcription repressor activity 1.23901105851653 bayes_pls_golite062009
growth factor binding 1.21242049144353 bayes_pls_golite062009
transcription factor activity 1.19760118797575 bayes_pls_golite062009
protein binding 1.17809977833322 bayes_pls_golite062009
transmembrane receptor protein tyrosine kinase activity 1.08793833350628 bayes_pls_golite062009
platelet-derived growth factor receptor binding 1.04423921087796 bayes_pls_golite062009
peptide antigen binding 1.03871842737922 bayes_pls_golite062009
G-protein coupled receptor activity 1.02428106476324 bayes_pls_golite062009
fibroblast growth factor binding 0.940492274094239 bayes_pls_golite062009
fibroblast growth factor receptor activity 0.83975918695548 bayes_pls_golite062009
protein complex binding 0.83543827718565 bayes_pls_golite062009
peptide binding 0.729048089532569 bayes_pls_golite062009
integrin binding 0.599569390248921 bayes_pls_golite062009
protein kinase activity 0.274138794214258 bayes_pls_golite062009
carbohydrate binding 0.0389714345254086 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle