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Protein Overview: ceh-6

General Information:
Name(s) found: ceh-6 / CE28045 [WormBase]
Description(s) found:
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  • WBGene00000431 locus:ceh-6 Homeobox protein ceh-6 status:Confirmed UniProt:P20268 protein_id:CAB00031.2 [WormBase]
  • gi|9966509|gb|AAG10298.1|AF286377_1 POU family III homeodomain protein CEH-6 [Caenorhabditis elegans] [NCBI NR]
  • gi|21264443|sp|P20268.3|HM06_CAEEL RecName: Full=Homeobox protein ceh-6 [NCBI NR]
  • gi|17506277|ref|NP_492304.1| Homeobox family member (ceh-6) [Caenorhabditis elegans] [NCBI NR]
  • gi|14530517|emb|CAB00031.2| C. elegans protein K02B12.1, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • Homeobox protein ceh-6 OS=Caenorhabditis elegans GN=ceh-6 PE=2 SV=3 [Swiss-Prot]
  • [wormpep67.fasta]
  • CE28045 WBGene00000431 locus:ceh-6 Homeobox domain, Pou domain - N-terminal to homeobox domain status:Confirmed SW:P20268 protein_id:CAB00031.2 [wormpep150.fasta]
  • 28045 WBGene00000431 locus:ceh-6 Homeobox domain, Pou domain - N-terminal to homeobox domain status:Confirmed SW:P20268 protein_id:CAB00031.2 [wormpep130-phg-ecoli-orf-rand.fasta]
  • C.Elegans Homeobox (42.6 kD) (ceh-6) [Caenorhabditis elegans]gi|14530517|emb|CAB00031.2| Hypothetical protein K02B12.1 [Caenorhabditis elegans]gi|9966509|gb|AAG10298.1| POU family III homeodomain protein CEH-6 [Caenorhabditis elegans]gi|21264443|sp|P20 [nrdb_11152004_Chlamydomonas]
  • locus:ceh-6 Homeobox domain, Pou domain - N-terminal to homeobox domain status:Confirmed SW:P20268 protein_id:CAB00031.2 [wormpep115.fasta.reversed]
  • CE28045 locus:ceh-6 Homeobox domain, Pou domain - N-terminal to homeobox domain status:Confirmed SW:P20268 protein_id:CAB00031.2 [wormpep80.hongbin]
  • CE28045 WBGene00000431 locus:ceh-6 Homeobox domain, Pou domain - N-terminal to homeobox domain status:Confirmed UniProt:P20268 protein_id:CAB00031.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE28045 WBGene00000431 locus:ceh-6 Homeobox domain, Pou domain - N-terminal to homeobox domain status:Confirmed UniProt:P20268 protein_id:CAB00031.2| [wormORF-contam.fasta]
  • Hypothetical protein K02B12.1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • C.Elegans Homeobox family member (ceh-6) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • POU family III homeodomain protein CEH-6 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Homeobox protein ceh-6 [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE28045 WBGene00000431 locus:ceh-6 status:Confirmed UniProt:P20268 protein_id:CAB00031.2 Homeobox protein ceh-6 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 380 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][IEALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: molting cycle, protein-based cuticle [IMPLink to PubMed article]
    locomotory behavior [IMPLink to PubMed articleLink to PubMed article]
    nematode larval development [IMPLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    post-embryonic body morphogenesis [IMPLink to PubMed article]
    cell differentiation [IMPLink to PubMed article]
    regulation of transcription, DNA-dependent [IEALink to PubMed article]
    gamete generation [IMPLink to PubMed article]
    regulation of transcription [TASLink to PubMed article]
    excretion [IMPLink to PubMed article]
    growth [IMPLink to PubMed article]
    Molecular Function: transcription factor activity [IEALink to PubMed article][ISSLink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLIPSSSSIP SSLSASASDS EPSSLNGSGI SDQNILPNYH LHHHLINENE MEAANYAQVI  60
   61 KPTCEAFQDW PHTPMLYQQP QLHFMLPQHD WAYPHLAQSL PPPHHLTPST AAVAAATIAS 120
  121 QSSIINQTSV VTSTPSCQIK QEVERPEIIQ RLMPPWPPAY QFSCDDSGSV SGAGGPHQPL 180
  181 SDISDDSEQT CPDDLEGFAK QFKQRRIKLG YTQADVGVAL GTLYGNIFSQ TTICRFEALQ 240
  241 LSFKNMCKLK PLLFKWLEEA DSTTGSPNST FEKMTGQAGR KRKKRTSIEV NVKSRLEFHF 300
  301 QSNQKPNAQE ITQVAMELQL EKEVVRVWFC NRRQKEKRIA PNQYDAPHPM ALNNGYPMTA 360
  361 DLFPYQAVVN HYTQQSPRQQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..157] MSA 5.744997 View MSA. No confident structure predictions are available.
    2 View Details [158..380] PSI-BLAST 28.0 TERNARY COMPLEX OF THE DNA BINDING DOMAINS OF THE OCT1 AND SOX2 TRANSCRIPTION FACTORS WITH A 19MER OLIGONUCLEOTIDE FROM THE HOXB1 REGULATORY ELEMENT

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • DNA binding
    		•  5.51228466689923 bayes_pls_golite062009
  • nucleic acid binding
    		•  5.37468811865033 bayes_pls_golite062009
  • transcription regulator activity
    		•  5.05236457497789 bayes_pls_golite062009
  • transcription factor activity
    		•  3.89464979825638 bayes_pls_golite062009
  • binding
    		•  3.66501723413351 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  3.25218945600666 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  3.22754992035091 bayes_pls_golite062009
  • transcription activator activity
    		•  3.15886611325686 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.75958281319075 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  1.62096064323298 bayes_pls_golite062009
  • protein binding
    		•  1.55649304400241 bayes_pls_golite062009
  • chromatin binding
    		•  1.2739759748489 bayes_pls_golite062009
  • transcription factor binding
    		•  1.02788976342343 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.92393807212912 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.8718993114781 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.81316180547536 bayes_pls_golite062009
  • promoter binding
    		•  0.22765608166458 bayes_pls_golite062009
  • catalytic activity
    		•  0.00446472034106909 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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