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Protein Overview: shl-1

General Information:
Name(s) found: shl-1 / CE27528 [WormBase]
Description(s) found:
Found 16 descriptions.
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  • WBGene00022240 locus:shl-1 status:Partially_confirmed UniProt:Q95XD1 protein_id:AAK68591.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 609 amino acids

    Gene Ontology:
    Cellular Component: voltage-gated potassium channel complex [IEALink to PubMed article]
    membrane [IEALink to PubMed article]
    Biological Process: potassium ion transport [IEALink to PubMed article]
    ion transport [IEALink to PubMed article]
    Molecular Function: voltage-gated potassium channel activity [IEALink to PubMed article]
    ion channel activity [IEALink to PubMed article]
    protein binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASVAAWLPF ARAAAIGWVP ISRQPMPQAP VAIQAKDLAV DHVSDEKLAI NISGRRFETW  60
   61 KNTLEKFPET LLGSNEKEFF YDEDTGEYFF DRDPDIFRHI LTFYRTGKLH YPRHECLVAY 120
  121 DEELSFFGIM PDLISDCCYE DYKDKKRENQ ERLQEERVEN ADISTLKLSL KEKMWAAFEN 180
  181 PHTTSIALVF YYVIGFFIAV SVMCNIVETI PCGYEDNVSV TCGEAYEEQF FVIDTACVII 240
  241 FTIEYFLRLI SAPDRIKFMR SIMSVIDVIA IMPYYVSLVL TDNKDVSGLF VTLRVFRVFR 300
  301 IFKFSRHSQG LRILGYTLKS CASELGFLVF SLAMAIIIFA TIMYYAEKKV DATRFTSIPS 360
  361 AFWYTIVTLT TLGYGDMVPS TIMGKIVGGV CSLSGVLVIA LPVPVIVSNF SRIYHQNQRA 420
  421 DKRKAQKKAR LARIRIVKNA SGLALFNKKR AHEARMLAFE QGHLSFDALR DEDIFEIQHH 480
  481 HLLQCLEKAT EREFVESEVM FEGGRNTPPP SETASLKGKT KRKRRLCCVS KENEEMEELD 540
  541 RETRVTFNQN MDQICELPKP DEMELNHRNN DKICVSQLWK YKIEVKLTFY VQFFFFQFSR 600
  601 SVDKVLFIF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..417] PSI-BLAST 77.39794 Mammalian Shaker Kv1.2 potassium channel- beta subunit complex
    2 View Details [418..609] PSI-BLAST 8.39794 Inward rectifier potassium channel Kirbac1.1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • potassium channel activity
    		•  11.7251017123146 bayes_pls_golite062009
  • voltage-gated potassium channel activity
    		•  11.6633540248684 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  10.8390941878925 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  10.6070925040712 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  10.5829074022385 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  9.5007353467592 bayes_pls_golite062009
  • cation channel activity
    		•  9.28297361124708 bayes_pls_golite062009
  • ion channel activity
    		•  8.57431827568433 bayes_pls_golite062009
  • gated channel activity
    		•  8.43134896985477 bayes_pls_golite062009
  • channel activity
    		•  8.342756944087 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  8.342756944087 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  8.33787087080341 bayes_pls_golite062009
  • ligand-gated ion channel activity
    		•  6.95707999757678 bayes_pls_golite062009
  • ligand-gated channel activity
    		•  6.95707999757678 bayes_pls_golite062009
  • inward rectifier potassium channel activity
    		•  6.12117505063719 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  4.76120513730507 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.65789393289521 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  4.23730629384621 bayes_pls_golite062009
  • G-protein activated inward rectifier potassium channel activity
    		•  3.55541781989473 bayes_pls_golite062009
  • ATP-activated inward rectifier potassium channel activity
    		•  3.06706619839151 bayes_pls_golite062009
  • transporter activity
    		•  2.46466249895824 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.37642404692102 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.37262306131842 bayes_pls_golite062009
  • binding
    		•  1.77589663168522 bayes_pls_golite062009
  • protein binding
    		•  1.18387449987737 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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