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Protein Overview: ceh-18

General Information:
Name(s) found: ceh-18 / CE25674 [WormBase]
Description(s) found:
Found 22 descriptions.
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  • WBGene00000441 locus:ceh-18 Homeobox protein ceh-18 status:Confirmed UniProt:P41934 protein_id:CCD71431.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 542 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][IEALink to PubMed article]
    Biological Process: ovulation from ovarian follicle [IMPLink to PubMed article]
    oocyte maturation [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    epidermis development [IMPLink to PubMed article]
    regulation of transcription, DNA-dependent [IEALink to PubMed article]
    germ cell migration [IMPLink to PubMed article]
    Molecular Function: transcription factor activity [IEALink to PubMed article][ISSLink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNTLENTFQF LAEVFEANGG CLVTERVSPS LSGASKRKSR PVKRIITEDE VIPEEEVVEE  60
   61 EEEEKVEQPS EEVTCPAMQV DATDAILASL RQIANNDLSE HCIREDEGNT SAEVFSNGNG 120
  121 EDMEQAGLAG TDLLRRVADM LQGNHNGSLN SHFLQQQFAA FKETVDPTPV STNGNGLLTP 180
  181 ITTQLSPLFT STDAFNSPEK LLQAIMTPSL GFLGANGLGA SNSGLLSSPL IAPSPTLLQS 240
  241 LMNTPTQPTA SLTPKKAENR PPVVSQTLKA SKRRLFDDTS RIEAASMSGD DRIDMNELEA 300
  301 FAQTFKKQRI KFGFTQGDVG VALGKRYGTD FSQTTISRFE ALNLSFKNMC KLRPLLKEWL 360
  361 ADVEMAIEGG ATVTDLIDKK TIHNGNHHTI HHVDIHETSI SNSISSVTAS SLLSREQHVK 420
  421 RRRKRTNLDM NQRNALDTFF ALNPRPDHDK MTDIANSLEL DRDVVRVWFC NRRQKMRRVD 480
  481 EPIEGEMVTP SVSPVFPHFS SMSALEQIQE AARLASCQAS NDDSDGTSGS PDAPSNDGCS 540
  541 DL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..106] PSI-BLAST 14.0 Trypanosoma sialidase, C-terminal domain; Trypanosoma sialidase
    2 View Details [107..260] MSA 2.274994 View MSA. No confident structure predictions are available.
    3 View Details [261..542] PSI-BLAST 16.69897 TERNARY COMPLEX OF THE DNA BINDING DOMAINS OF THE OCT1 AND SOX2 TRANSCRIPTION FACTORS WITH A 19MER OLIGONUCLEOTIDE FROM THE HOXB1 REGULATORY ELEMENT

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • DNA binding
    		•  5.51228466689923 bayes_pls_golite062009
  • nucleic acid binding
    		•  5.37468811865033 bayes_pls_golite062009
  • transcription regulator activity
    		•  5.05236457497789 bayes_pls_golite062009
  • transcription factor activity
    		•  3.89464979825638 bayes_pls_golite062009
  • binding
    		•  3.66501723413351 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  3.25218945600666 bayes_pls_golite062009
  • transcription activator activity
    		•  3.15886611325686 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.32042014361691 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.75958281319075 bayes_pls_golite062009
  • protein binding
    		•  1.55649304400241 bayes_pls_golite062009
  • transcription factor binding
    		•  1.02788976342343 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.8718993114781 bayes_pls_golite062009
  • chromatin binding
    		•  0.62573870961765 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.34211447646243 bayes_pls_golite062009
  • catalytic activity
    		•  0.00446472034106909 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.81

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle