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Protein Overview: vab-3

General Information:
Name(s) found: vab-3 / CE24899 [WormBase]
Description(s) found:
Found 22 descriptions.
SHOW ALL
  • WBGene00006870 locus:vab-3 status:Confirmed UniProt:G5EDS1 protein_id:CAA90186.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 455 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][IEALink to PubMed article]
    Biological Process: multicellular organismal development [IEALink to PubMed article]
    cell fate commitment [IMPLink to PubMed article]
    anterior/posterior pattern formation [IMPLink to PubMed article]
    regulation of transcription, DNA-dependent [IEALink to PubMed article][ISSLink to PubMed article]
    tail tip morphogenesis [IMPLink to PubMed articleLink to PubMed article]
    regulation of cell adhesion [IMPLink to PubMed article]
    positive regulation of transcription from RNA polymerase II promoter [IMPLink to PubMed article]
    Molecular Function: transcription factor activity [IEALink to PubMed article][ISSLink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDAGHTGVN QLGGVFVNGR PLPDATRQRI VDLAHKGCRP CDISRLLQVS NGCVSKILCR  60
   61 YYESGTIRPR AIGGSKPRVA TSDVVEKIED YKRDQPSIFA WEIRDKLLAD NICNNETIPS 120
  121 VSSINRVLRN LAAKKEQVTM QTELYDRIRI VDNFPYNSSW YGQWPIPMNG AVGLNPFVPA 180
  181 PLIEPKTEGE FEKDEDQKPP TEPEDDAAAR MRLKRKLQRN RTSFTQVQIE SLEKEFERTH 240
  241 YPDVFARERL AQKIQLPEAR IQVWFSNRRA KWRREEKMRN KRSSGTMDSS LSNGTPTPTP 300
  301 GSVTGSNMTN PIGSPASTPN RFPSNNSANL PTTNFVPQTS QMYAGLSQPA MDPYSFGIAN 360
  361 GFSMAPYPQV TDFQPHHMFQ GRSPYDFPYP RMPTNGHGFQ QSMSPATTAV GDIPTLSSGM 420
  421 SLPVSAVLNS IDPSLTHSQM HELSDLTQEH YWRPQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..203] PSI-BLAST 50.30103 Pax-5
    2 View Details [204..320] PSI-BLAST 12.522879 Solution structure of the homeobox domain of the human paired box protein Pax-6
    3 View Details [321..455] MSA 4.374996 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  5.13863038737912 bayes_pls_golite062009
  • DNA binding
    		•  4.66369707598026 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.51452285155271 bayes_pls_golite062009
  • transcription factor activity
    		•  4.06706589695599 bayes_pls_golite062009
  • transcription repressor activity
    		•  3.55154985983449 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  3.5139760613123 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  3.16896789933192 bayes_pls_golite062009
  • transcription activator activity
    		•  3.10621734076555 bayes_pls_golite062009
  • binding
    		•  3.02779747447702 bayes_pls_golite062009
  • protein binding
    		•  1.88087411289001 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.73068440195944 bayes_pls_golite062009
  • chromatin binding
    		•  1.68956710349366 bayes_pls_golite062009
  • transcription corepressor activity
    		•  1.49423102874486 bayes_pls_golite062009
  • transcription factor binding
    		•  1.40653841901929 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.84983974758882 bayes_pls_golite062009
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  5.13863038737912 bayes_pls_golite062009
  • DNA binding
    		•  4.66369707598026 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.51452285155271 bayes_pls_golite062009
  • transcription factor activity
    		•  4.06706589695599 bayes_pls_golite062009
  • transcription repressor activity
    		•  3.55154985983449 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  3.5139760613123 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  3.16896789933192 bayes_pls_golite062009
  • transcription activator activity
    		•  3.10621734076555 bayes_pls_golite062009
  • binding
    		•  3.02779747447702 bayes_pls_golite062009
  • protein binding
    		•  1.88087411289001 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.73068440195944 bayes_pls_golite062009
  • chromatin binding
    		•  1.68956710349366 bayes_pls_golite062009
  • transcription corepressor activity
    		•  1.49423102874486 bayes_pls_golite062009
  • transcription factor binding
    		•  1.40653841901929 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.84983974758882 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle