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Protein Overview: npp-18

General Information:
Name(s) found: npp-18 / CE16629 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00003804 locus:npp-18 Nucleoporin SEH1 status:Confirmed UniProt:O45933 protein_id:CAA16333.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 363 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: chromosome segregation [IMPLink to PubMed article]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQEDDSVKPF QTVGAHRDLI HCVSFDPHGR RMATCASDMT MAIWDRKPDG NWRRSAHWKC  60
   61 HGGAVWRVIW AHPEFGQIVA TCSYDRTIVI WEEQIVRSEK DLKQKESQWI RRTIISDNRS 120
  121 DVTDICFSPR HLGLMMASCN VLGTVRIYEA PDIVDASRWN LIHELQAFHT RCGCVTWSLS 180
  181 RMHRPLIAVG SDEKKAENKK RVVIYENIDG LRKWQRINSL VFDLPCPITD LKFSPISMVD 240
  241 SHQLAVASGD VHVYNIKVAR SAILEEDGVE NPIQLADYNL IKVALLGDHR KAWRLRYNLM 300
  301 GSVISSTSLD GTLRSWKSLF VNQWVKLSEM NVDDYVPSPE EVRAFISSKT TERLPSQLEK 360
  361 TYF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..363] PSI-BLAST 61.154902 PAF-AH Holoenzyme: Lis1/Alfa2

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.42570478946173 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.95667720244696 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.90457914882449 bayes_pls_golite062009
  • GTPase activity
    		•  1.66665311782591 bayes_pls_golite062009
  • snoRNA binding
    		•  1.61553185503007 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  1.59258100795958 bayes_pls_golite062009
  • DNA binding
    		•  1.38475369554616 bayes_pls_golite062009
  • protein binding
    		•  1.21879977456466 bayes_pls_golite062009
  • transporter activity
    		•  1.21549336905926 bayes_pls_golite062009
  • protein transporter activity
    		•  0.964340340346761 bayes_pls_golite062009
  • transcription factor activity
    		•  0.804334981068351 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.734793983890004 bayes_pls_golite062009
  • structural molecule activity
    		•  0.721739615005709 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.577438981735303 bayes_pls_golite062009
  • signal transducer activity
    		•  0.577438981735303 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.560226369775279 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  0.535041400676017 bayes_pls_golite062009
    		• 0.53274018413176 bayes_pls_golite062009
  • transcription factor binding
    		•  0.412844855996155 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.359536347486199 bayes_pls_golite062009
  • receptor activity
    		•  0.322599767074871 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.19391619547146 bayes_pls_golite062009
  • hydrolase activity
    		•  0.181211933860468 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.168317261786777 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.132660456600365 bayes_pls_golite062009
  • kinase activity
    		•  0.127621956173205 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.00954741955203087 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.00585398682921312 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle