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Protein Overview: cpl-1

General Information:
Name(s) found: cpl-1 / CE16333 [WormBase]
Description(s) found:
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  • WBGene00000776 locus:cpl-1 status:Confirmed UniProt:O45734 protein_id:CAB07275.1 [WormBase]
  • pir||T24387 probable cysteine proteinase (EC 3.4.22.-) T03E6.7 - Caenorhabditis elegans [NCBI NR]
  • gi|3879367|emb|CAB07275.1| C. elegans protein T03E6.7, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|17563798|ref|NP_507199.1| CathePsin L family member (cpl-1) [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • CE16333 WBGene00000776 locus:cpl-1 cathepsin-like protease status:Confirmed TR:O45734 protein_id:CAB07275.1 [wormpep150.fasta]
  • 16333 WBGene00000776 locus:cpl-1 cathepsin-like protease status:Confirmed TR:O45734 protein_id:CAB07275.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • CathePsin L (38.1 kD) (cpl-1) [Caenorhabditis elegans]gi|3879367|emb|CAB07275.1| Hypothetical protein T03E6.7 [Caenorhabditis elegans]gi|7507001|pir||T24387 probable cysteine proteinase (EC 3.4.22.-) T03E6.7 - Caenorhabditis elegans [nrdb_11152004_Chlamydomonas]
  • locus:cpl-1 cathepsin-like protease status:Confirmed TR:O45734 protein_id:CAB07275.1 [wormpep115.fasta.reversed]
  • CE16333 cathepsin-like protease status:Confirmed TR:O45734 protein_id:CAB07275.1 [wormpep80.hongbin]
  • CE16333 WBGene00000776 locus:cpl-1 cathepsin-like protease status:Confirmed UniProt:O45734_CAEEL protein_id:CAB07275.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE16333 WBGene00000776 locus:cpl-1 cathepsin-like protease status:Confirmed UniProt:O45734_CAEEL protein_id:CAB07275.1| [wormORF-contam.fasta]
  • CathePsin L family member (cpl-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein T03E6.7 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE16333 WBGene00000776 locus:cpl-1 cathepsin-like protease status:Confirmed UniProt:O45734 protein_id:CAB07275.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE16333 WBGene00000776 locus:cpl-1 status:Confirmed UniProt:O45734 protein_id:CAB07275.1 [wormpep246-ecoli-contam.fasta]
  • CathePsin L family OS=Caenorhabditis elegans GN=cpl-1 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 337 amino acids

    Gene Ontology:
    Cellular Component: yolk granule [IDALink to PubMed article]
    vesicle lumen [IDALink to PubMed article]
    Biological Process: locomotory behavior [IMPLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed articleLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    proteolysis [IEALink to PubMed article]
    Molecular Function: cysteine-type endopeptidase activity [IEALink to PubMed article]
    cysteine-type peptidase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNRFILLALV AAVVAVNSAK LSRQIESAIE KWDDYKEDFD KEYSESEEQT YMEAFVKNMI  60
   61 HIENHNRDHR LGRKTFEMGL NHIADLPFSQ YRKLNGYRRL FGDSRIKNSS SFLAPFNVQV 120
  121 PDEVDWRDTH LVTDVKNQGM CGSCWAFSAT GALEGQHARK LGQLVSLSEQ NLVDCSTKYG 180
  181 NHGCNGGLMD QAFEYIRDNH GVDTEESYPY KGRDMKCHFN KKTVGADDKG YVDTPEGDEE 240
  241 QLKIAVATQG PISIAIDAGH RSFQLYKKGV YYDEECSSEE LDHGVLLVGY GTDPEHGDYW 300
  301 IVKNSWGAGW GEKGYIRIAR NRNNHCGVAT KASYPLV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..337] PSI-BLAST 91.0 (Pro)cathepsin L

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • peptidase activity
    		•  4.90619850296986 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  4.64381885397949 bayes_pls_golite062009
  • endopeptidase activity
    		•  3.75054525912786 bayes_pls_golite062009
  • hydrolase activity
    		•  3.74079711298952 bayes_pls_golite062009
  • cysteine-type peptidase activity
    		•  2.71117522993364 bayes_pls_golite062009
  • cysteine-type endopeptidase activity
    		•  1.95802900199539 bayes_pls_golite062009
  • binding
    		•  1.29265216891074 bayes_pls_golite062009
  • catalytic activity
    		•  1.05972260874031 bayes_pls_golite062009
  • protein binding
    		•  0.774177093888744 bayes_pls_golite062009
  • small conjugating protein-specific protease activity
    		•  0.649171767629235 bayes_pls_golite062009
  • thiolester hydrolase activity
    		•  0.59115205419466 bayes_pls_golite062009
  • kininogen binding
    		•  0.41283715939055 bayes_pls_golite062009
  • signal transducer activity
    		•  0.12644030784065 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.12644030784065 bayes_pls_golite062009
  • ubiquitin-specific protease activity
    		•  0.0101379718864654 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle