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Protein Overview: rpa-2

General Information:
Name(s) found: rpa-2 / CE12414 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00019767 locus:rpa-2 status:Confirmed UniProt:Q95Y97 protein_id:CCD64225.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 288 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: DNA repair [IMPLink to PubMed article]
    locomotory behavior [IMPLink to PubMed articleLink to PubMed article]
    hermaphrodite genitalia development [IMPLink to PubMed article]
    morphogenesis of an epithelium [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    oviposition [IMPLink to PubMed article]
    gamete generation [IMPLink to PubMed article]
    Molecular Function: nucleic acid binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWNETVEHEN AGNGWAAGES SFMTDRKPDS KATTLGERLP VPVTISNLIE HFSAQDDKYV  60
   61 VGTFRFATVL TVGIVKDISQ DGTTYTYDLC DPNNTEMEYR TLKYDNEGST FDHSSIVEGT 120
  121 RVRAIGKLKG FDGNNTIMLF NITPVEDDKD FTIFELEAEA ARLFFQKNVS EKLKSVDSDG 180
  181 FQGMLAPPKS RMSQTSHQSS QGSDTKERLY AQPQKVMTGA NQGDVLRERI TAVLMAVPEG 240
  241 SRDEGRHVSW IAEQIQETNI SIVRKCVGEM VENGLVYTTV DEETVSAI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-1 hcp1 IP from december2004 Cheeseman, I.M., et al. (2005)
    View Run hcp-2 hcp2 ip from december Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..288] PSI-BLAST 72.69897 No description for 2pi2A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • single-stranded DNA binding
    		•  3.59212997362902 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  3.53214384646348 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.27576062206528 bayes_pls_golite062009
  • binding
    		•  2.63617204791771 bayes_pls_golite062009
  • DNA binding
    		•  2.56243510083541 bayes_pls_golite062009
  • ribonuclease activity
    		•  2.19009583193838 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  2.13063800565247 bayes_pls_golite062009
  • structural molecule activity
    		•  1.9177190829469 bayes_pls_golite062009
  • telomeric DNA binding
    		•  1.7847835613194 bayes_pls_golite062009
  • single-stranded telomeric DNA binding
    		•  1.48033977789232 bayes_pls_golite062009
  • telomerase inhibitor activity
    		•  1.25988289474883 bayes_pls_golite062009
  • DNA helicase activity
    		•  1.12203697857261 bayes_pls_golite062009
  • exoribonuclease activity
    		•  1.07725510169091 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  1.05277881555112 bayes_pls_golite062009
  • DNA-directed RNA polymerase activity
    		•  0.79554655100991 bayes_pls_golite062009
  • RNA polymerase activity
    		•  0.79554655100991 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.756094573447167 bayes_pls_golite062009
  • hydrolase activity
    		•  0.724860465280978 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.638831894247026 bayes_pls_golite062009
  • 3'-5'-exoribonuclease activity
    		•  0.592562824942671 bayes_pls_golite062009
  • nuclease activity
    		•  0.57381531077345 bayes_pls_golite062009
  • translation regulator activity
    		•  0.515576958825022 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.468402630523277 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.378383789953688 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.325774164899685 bayes_pls_golite062009
  • exonuclease activity
    		•  0.28313884527829 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.21650406007586 bayes_pls_golite062009
  • translation initiation factor activity
    		•  0.2080607201312 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  0.0954216620147701 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.0909806857084046 bayes_pls_golite062009
  • transcription factor activity
    		•  0.0591886273075271 bayes_pls_golite062009
  • protein binding
    		•  0.0528188351789111 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  0.0179535526984695 bayes_pls_golite062009
  • helicase activity
    		•  0.0121541775159524 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

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    Created and Maintained by: Michael Riffle