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Protein Overview: bli-4

General Information:
Name(s) found: bli-4 / CE11730 [WormBase]
Description(s) found:
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  • WBGene00000254 locus:bli-4 Endoprotease bli-4 status:Confirmed UniProt:P51559 protein_id:CCD70036.1 [WormBase]
  • gi|71988301|ref|NP_001021541.1| BLIstered cuticle family member (bli-4) [Caenorhabditis elegans] [NCBI NR]
  • gi|2773245|gb|AAB96756.1| Blistered cuticle protein 4, isoform b [Caenorhabditis elegans] [NCBI NR]
  • gi|25289985|pir||F87803 protein bli-4B [imported] - Caenorhabditis elegans [NCBI NR]
  • [wormpep67.fasta]
  • Blistered cuticle protein 4, isoform b [Caenorhabditis elegans]gi|25289985|pir||F87803 protein bli-4B [imported] - Caenorhabditis elegans [nrdb_11152004_Chlamydomonas]
  • CE11730 WBGene00000254 locus:bli-4 endoprotease status:Confirmed SW:P51559 protein_id:AAB96756.1 [wormpep150.fasta]
  • 11730 WBGene00000254 locus:bli-4 endoprotease status:Confirmed SW:P51559 protein_id:AAB96756.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • locus:bli-4 endoprotease status:Partially_confirmed SW:P51559 protein_id:AAB96756.1 [wormpep115.fasta.reversed]
  • CE11730 locus:bli-4 endoprotease status:Partially_confirmed [wormpep80.hongbin]
  • CE11730 WBGene00000254 locus:bli-4 endoprotease status:Confirmed UniProt:P51559 protein_id:AAB96756.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE11730 WBGene00000254 locus:bli-4 endoprotease status:Confirmed UniProt:P51559 protein_id:AAB96756.1| [wormORF-contam.fasta]
  • K04F10.4b [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Blistered cuticle protein 4, isoform b [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • protein bli-4B [imported] - Caenorhabditis elegans [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE11730 WBGene00000254 locus:bli-4 endoprotease status:Confirmed UniProt:P51559 protein_id:CCD70036.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE11730 WBGene00000254 locus:bli-4 status:Confirmed UniProt:P51559 protein_id:CCD70036.1 Endoprotease bli-4 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 730 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    Biological Process: embryonic development [IMPLink to PubMed article]
    molting cycle, protein-based cuticle [IMPLink to PubMed articleLink to PubMed article]
    collagen and cuticulin-based cuticle development [IMPLink to PubMed article]
    locomotory behavior [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    proteolysis [IEALink to PubMed article]
    growth [IMPLink to PubMed articleLink to PubMed article]
    positive regulation of multicellular organism growth [IMPLink to PubMed articleLink to PubMed article]
    Molecular Function: proprotein convertase activity [ISSLink to PubMed article]
    subtilase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRISIGRIAW QILAVLIAVA FTIEHDSICD ESIGACGEPI HTVIRLAKRD DELARRIAAD  60
   61 HDMHVKGDPF LDTHYFLYHS ETTRTRRHKR AIVERLDSHP AVEWVEEQRP KKRVKRDYIL 120
  121 LDNDVHHSNP FRRSVLNRDG TRRAQRQQPQ SPREIPSLPF PDPLYKDQWY LHGGAVGGYD 180
  181 MNVRQAWLQG YAGRNVSVSI LDDGIQRDHP DLAANYDPLA STDINDHDDD PTPQNNGDNK 240
  241 HGTRCAGEVA ALAGNNQCGV GVAFKAKIGG VRMLDGAVSD SVEAASLSLN QDHIDIYSAS 300
  301 WGPEDDGKTF DGPGPLAREA FYRGIKNGRG GKGNIFVWAS GNGGSRQDSC SADGYTTSVY 360
  361 TLSISSATYD NHRPWYLEEC PSSIATTYSS ADFRQPAIVT VDVPGGCTDK HTGTSASAPL 420
  421 AAGIIALALE ANPELTWRDM QHLVLRTANW KPLENNPGWS RNGVGRMVSN KFGYGLIDGG 480
  481 ALVNMAKTWK TVPEQHICTY EYRLANPNPR PIVGRFQLNF TLDVNGCESG TPVLYLEHVQ 540
  541 VHATVRYLKR GDLKLTLFSP SGTRSVLLPP RPQDFNANGF HKWPFLSVQQ WGEDPRGTWL 600
  601 LMVESVTTNP AATGTFHDWT LLLYGTADPA QSGDPVYSAT PATSQGVLSR VHQLTSQGDE 660
  661 VVERIRNHWE VTLEESSHWN WEHAREHKSL QELNSSSRTH SFLYSFTKFQ PIFLIILVCI 720
  721 FDAIHRQFAV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..158] PSI-BLAST 9.045757 High Resolution Crystal Structure of the Intact Pro-Kumamolisin, a Sedolisin Type Proteinase (previously called Kumamolysin or KSCP)
    2 View Details [159..628] PSI-BLAST 93.522879 Furin, C-terminal domain; Furin, N-terminal domain
    3 View Details [629..730] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • peptidase activity
    		•  4.77677490610016 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  4.40501322467328 bayes_pls_golite062009
  • serine hydrolase activity
    		•  4.30899317351154 bayes_pls_golite062009
  • serine-type peptidase activity
    		•  4.29545891350519 bayes_pls_golite062009
  • nerve growth factor binding
    		•  3.93556598541015 bayes_pls_golite062009
  • endopeptidase activity
    		•  3.83336601331518 bayes_pls_golite062009
  • serine-type endopeptidase activity
    		•  3.71508033196614 bayes_pls_golite062009
  • neurotrophin binding
    		•  2.36320382357038 bayes_pls_golite062009
  • hydrolase activity
    		•  2.05732080397524 bayes_pls_golite062009
  • eukaryotic cell surface binding
    		•  1.50287724152407 bayes_pls_golite062009
  • binding
    		•  1.08901362883653 bayes_pls_golite062009
  • catalytic activity
    		•  0.597535457699629 bayes_pls_golite062009
  • exopeptidase activity
    		•  0.42083764849682 bayes_pls_golite062009
  • protein binding
    		•  0.380935140681308 bayes_pls_golite062009
  • receptor binding
    		•  0.222369968782666 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  0.11649614154172 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle