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Protein Overview: hda-1

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

  BAIT COMMENTS PUBLICATION
View Run hcp-1 hcp1 IP from december2004 Cheeseman, I.M., et al. (2005)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data


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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#   Region(s) Method Confidence Match Description
1 View Details [1..388] PSI-BLAST 94.0 Crystal Structure of human HDAC8 complexed with Trichostatin A
2 View Details [389..461] MSA 1.097991 View MSA. No confident structure predictions are available.

Functions predicted (by domain):

# Gene Ontology predictions
1
Term Confidence Notes
  • protein deacetylase activity
  • 12.8220438463909 bayes_pls_golite062009
  • histone deacetylase activity
  • 12.6231784270509 bayes_pls_golite062009
  • deacetylase activity
  • 11.5037545953213 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
  • 9.39837596691907 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
  • 9.35288901670927 bayes_pls_golite062009
  • histone deacetylase activity (H3-K16 specific)
  • 6.99181745976945 bayes_pls_golite062009
  • histone deacetylase activity (H3-K14 specific)
  • 4.16874113003585 bayes_pls_golite062009
  • histone methyltransferase activity (H3-K27 specific)
  • 3.8227021325477 bayes_pls_golite062009
  • histone deacetylase activity (H3-K9 specific)
  • 3.65015413158247 bayes_pls_golite062009
  • transcription repressor activity
  • 3.49362347258099 bayes_pls_golite062009
  • NAD-dependent protein deacetylase activity
  • 3.35999169984456 bayes_pls_golite062009
  • NAD-dependent histone deacetylase activity
  • 3.35999169984456 bayes_pls_golite062009
  • transcription regulator activity
  • 3.05701986980927 bayes_pls_golite062009
  • transcription factor binding
  • 2.19991964087943 bayes_pls_golite062009
  • hydrolase activity
  • 2.17916401684365 bayes_pls_golite062009
  • NAD-independent histone deacetylase activity
  • 2.1026758793482 bayes_pls_golite062009
  • nucleic acid binding
  • 2.09632179671955 bayes_pls_golite062009
  • transcription corepressor activity
  • 1.98907367314887 bayes_pls_golite062009
  • DNA binding
  • 1.982290944939 bayes_pls_golite062009
  • binding
  • 1.948738669065 bayes_pls_golite062009
  • protein binding
  • 1.77599011146146 bayes_pls_golite062009
  • catalytic activity
  • 1.68836803454021 bayes_pls_golite062009
  • histone methyltransferase activity (H3-K9 specific)
  • 1.48241147541212 bayes_pls_golite062009
  • specific transcriptional repressor activity
  • 1.37118634909958 bayes_pls_golite062009
  • transcription activator activity
  • 1.31578100431097 bayes_pls_golite062009
  • transcription factor activity
  • 1.24596588472933 bayes_pls_golite062009
  • transcription cofactor activity
  • 0.84972377395539 bayes_pls_golite062009
  • histone methyltransferase activity
  • 0.396822865624511 bayes_pls_golite062009
  • transferase activity
  • 0.323230424038105 bayes_pls_golite062009
  • chromatin binding
  • 0.104097933861351 bayes_pls_golite062009
    2 No functions predicted.




    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)


    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle