Protein Overview: CE06652

General Information:
Name(s) found:	CE06652 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00014095 locus:gdh-1 Glutamate dehydrogenase status:Confirmed UniProt:Q23621 protein_id:CAA98074.1 [WormBase] pir\|\|T28022 hypothetical protein ZK829.4 - Caenorhabditis elegans [NCBI NR] gi\|3881823\|emb\|CAA98074.1\| C. elegans protein ZK829.4, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] gi\|17544676\|ref\|NP_502267.1\| hypothetical protein ZK829.4 [Caenorhabditis elegans] [NCBI NR] [wormpep67.fasta] CE06652 WBGene00014095 glutamate dehydrogenase status:Confirmed TR:Q23621 protein_id:CAA98074.1 [wormpep150.fasta] 06652 WBGene00014095 glutamate dehydrogenase status:Confirmed TR:Q23621 protein_id:CAA98074.1 [wormpep130-phg-ecoli-orf-rand.fasta] glutamate dehydrogenase (58.8 kD) (4M719) [Caenorhabditis elegans]gi\|3881823\|emb\|CAA98074.1\| Hypothetical protein ZK829.4 [Caenorhabditis elegans]gi\|7511341\|pir\|\|T28022 hypothetical protein ZK829.4 - Caenorhabditis elegans [nrdb_11152004_Chlamydomonas] glutamate dehydrogenase status:Confirmed TR:Q23621 protein_id:CAA98074.1 [wormpep115.fasta.reversed] CE06652 glutamate dehydrogenase status:Confirmed TR:Q23621 protein_id:CAA98074.1 [wormpep80.hongbin] CE06652 WBGene00014095 glutamate dehydrogenase status:Confirmed UniProt:Q23621_CAEEL protein_id:CAA98074.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE06652 WBGene00014095 glutamate dehydrogenase status:Confirmed UniProt:Q23621_CAEEL protein_id:CAA98074.1\| [wormORF-contam.fasta] Hypothetical protein ZK829.4 [Caenorhabditis elegans] [nr-271106-contam.fasta] ZK829.4 [Caenorhabditis elegans] [nr-271106-contam.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE06652 WBGene00014095 glutamate dehydrogenase status:Confirmed UniProt:Q23621 protein_id:CAA98074.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta] CE06652 WBGene00014095 locus:gdh-1 glutamate dehydrogenase status:Confirmed UniProt:Q23621 protein_id:CAA98074.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta] CE06652 WBGene00014095 locus:gdh-1 status:Confirmed UniProt:Q23621 protein_id:CAA98074.1 Glutamate dehydrogenase [wormpep246-ecoli-contam.fasta] Glutamate dehydrogenase OS=Caenorhabditis elegans GN=gdh-1 PE=1 SV=1 [CAEEL.fasta.20160308]
Organism:	Caenorhabditis elegans
Length:	536 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	positive regulation of growth rate [IMP] cellular amino acid metabolic process [IEA]
Molecular Function:	oxidoreductase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSTLSRGAR SVAVRSYSAA TLDAHSQVLD EQKPMEEQVN PSFYKMVDFY FNKGAEVIAP  60
   61 KLAEELKSNS LSQKDKKNLV SGILGAIKPV NKVLYITFPI RRDNGEFEVI EAWRAQHSEH 120
  121 RTPTKGGIRY SLDVCEDEVK ALSALMTYKC AVVDVPFGGA KGGVKIDPKQ YTDYEIEKIT 180
  181 RRIAIEFAKK GFLGPGVDVP APDMGTGERE MGWIADTYAQ TIGHLDRDAS ACITGKPIVS 240
  241 GGIHGRVSAT GRGVWKGLEV FTNDADYMKM VGLDTGLAGK TAIIQGFGNV GLHTHRYLHR 300
  301 AGSKVIGIQE YDCAVYNPDG IHPKELEDWK DANGTIKNFP GAKNFDPFTE LMYEKCDIFV 360
  361 PAACEKSIHK ENASRIQAKI IAEAANGPTT PAADRILLAR GDCLIIPDMY VNSGGVTVSY 420
  421 FEWLKNLNHV SYGRLTFKYD EEANKMLLAS VQESLSKAVG KDCPVEPNAA FAAKIAGASE 480
  481 KDIVHSGLEY TMQRSGEAII RTAHKYNLGL DIRTAAYANS IEKVYNTYRT AGFTFT

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	hcp-1	hcp1 IP from december2004	Cheeseman, I.M., et al. (2005)
View Run	hcp-2	hcp2 ip from december	Cheeseman, I.M., et al. (2005)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
malate dehydrogenase activity	4.54055877372572	bayes_pls_golite062009
glutamate dehydrogenase (NADP+) activity	4.50065200228697	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor	4.08697502437308	bayes_pls_golite062009
oxidoreductase activity	3.54983447672782	bayes_pls_golite062009
malic enzyme activity	3.35473342014292	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	2.66605122152932	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor	2.66329970371321	bayes_pls_golite062009
retinol dehydrogenase activity	2.20121263385992	bayes_pls_golite062009
glutamate dehydrogenase [NAD(P)+] activity	2.15778057341677	bayes_pls_golite062009
catalytic activity	2.0643953589843	bayes_pls_golite062009
shikimate 5-dehydrogenase activity	1.82286236344978	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	1.81060491890041	bayes_pls_golite062009
binding	1.77370305872094	bayes_pls_golite062009
DNA binding	1.61355789916908	bayes_pls_golite062009
transcription regulator activity	1.55390653047158	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1.54527841865655	bayes_pls_golite062009
nucleic acid binding	1.48478425318425	bayes_pls_golite062009
malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity	1.3195473694323	bayes_pls_golite062009
transcription factor activity	0.91090893050278	bayes_pls_golite062009
transporter activity	0.793769336118517	bayes_pls_golite062009
structural molecule activity	0.75267483298133	bayes_pls_golite062009
steroid dehydrogenase activity	0.688300591674961	bayes_pls_golite062009
transmembrane transporter activity	0.635891484075352	bayes_pls_golite062009
ethanol binding	0.60130343317805	bayes_pls_golite062009
receptor activity	0.591732115418164	bayes_pls_golite062009
transmembrane receptor activity	0.565177620701637	bayes_pls_golite062009
retinol binding	0.52675367288453	bayes_pls_golite062009
protein binding	0.507836099271263	bayes_pls_golite062009
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	0.48368946932774	bayes_pls_golite062009
signal transducer activity	0.384212208916324	bayes_pls_golite062009
molecular transducer activity	0.384212208916324	bayes_pls_golite062009
substrate-specific transporter activity	0.300373102236296	bayes_pls_golite062009
active transmembrane transporter activity	0.239024094835991	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.165260811069909	bayes_pls_golite062009
transferase activity, transferring acyl groups	0.0992243118937675	bayes_pls_golite062009
NAD or NADH binding	0.0664389065992004	bayes_pls_golite062009
ion transmembrane transporter activity	0.0257250793986203	bayes_pls_golite062009

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.66

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..536]	PSI-BLAST	141.0	Glutamate dehydrogenase

Protein Overview: CE06652

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: