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View Structure Prediction Details

Protein: CE06652
Organism: Caenorhabditis elegans
Length: 536 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE06652.

Description E-value Query
Range		 Subject
Range
GLUD2 - glutamate dehydrogenase 2
 511.0 [0..5] [536..30]

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Predicted Domain #1
Region A:
Residues: [1-536] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSTLSRGAR SVAVRSYSAA TLDAHSQVLD EQKPMEEQVN PSFYKMVDFY FNKGAEVIAP  60
   61 KLAEELKSNS LSQKDKKNLV SGILGAIKPV NKVLYITFPI RRDNGEFEVI EAWRAQHSEH 120
  121 RTPTKGGIRY SLDVCEDEVK ALSALMTYKC AVVDVPFGGA KGGVKIDPKQ YTDYEIEKIT 180
  181 RRIAIEFAKK GFLGPGVDVP APDMGTGERE MGWIADTYAQ TIGHLDRDAS ACITGKPIVS 240
  241 GGIHGRVSAT GRGVWKGLEV FTNDADYMKM VGLDTGLAGK TAIIQGFGNV GLHTHRYLHR 300
  301 AGSKVIGIQE YDCAVYNPDG IHPKELEDWK DANGTIKNFP GAKNFDPFTE LMYEKCDIFV 360
  361 PAACEKSIHK ENASRIQAKI IAEAANGPTT PAADRILLAR GDCLIIPDMY VNSGGVTVSY 420
  421 FEWLKNLNHV SYGRLTFKYD EEANKMLLAS VQESLSKAVG KDCPVEPNAA FAAKIAGASE 480
  481 KDIVHSGLEY TMQRSGEAII RTAHKYNLGL DIRTAAYANS IEKVYNTYRT AGFTFT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 141.0
Match: 1l1fA
Description: Glutamate dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
malate dehydrogenase activity 4.54055877372572 bayes_pls_golite062009
glutamate dehydrogenase (NADP+) activity 4.50065200228697 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor 4.08697502437308 bayes_pls_golite062009
oxidoreductase activity 3.54983447672782 bayes_pls_golite062009
malic enzyme activity 3.35473342014292 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 2.66605122152932 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor 2.66329970371321 bayes_pls_golite062009
retinol dehydrogenase activity 2.20121263385992 bayes_pls_golite062009
glutamate dehydrogenase [NAD(P)+] activity 2.15778057341677 bayes_pls_golite062009
catalytic activity 2.0643953589843 bayes_pls_golite062009
shikimate 5-dehydrogenase activity 1.82286236344978 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH 1.81060491890041 bayes_pls_golite062009
binding 1.77370305872094 bayes_pls_golite062009
DNA binding 1.61355789916908 bayes_pls_golite062009
transcription regulator activity 1.55390653047158 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1.54527841865655 bayes_pls_golite062009
nucleic acid binding 1.48478425318425 bayes_pls_golite062009
malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity 1.3195473694323 bayes_pls_golite062009
transcription factor activity 0.91090893050278 bayes_pls_golite062009
transporter activity 0.793769336118517 bayes_pls_golite062009
structural molecule activity 0.75267483298133 bayes_pls_golite062009
steroid dehydrogenase activity 0.688300591674961 bayes_pls_golite062009
transmembrane transporter activity 0.635891484075352 bayes_pls_golite062009
ethanol binding 0.60130343317805 bayes_pls_golite062009
receptor activity 0.591732115418164 bayes_pls_golite062009
transmembrane receptor activity 0.565177620701637 bayes_pls_golite062009
retinol binding 0.52675367288453 bayes_pls_golite062009
protein binding 0.507836099271263 bayes_pls_golite062009
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.48368946932774 bayes_pls_golite062009
signal transducer activity 0.384212208916324 bayes_pls_golite062009
molecular transducer activity 0.384212208916324 bayes_pls_golite062009
substrate-specific transporter activity 0.300373102236296 bayes_pls_golite062009
active transmembrane transporter activity 0.239024094835991 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.165260811069909 bayes_pls_golite062009
transferase activity, transferring acyl groups 0.0992243118937675 bayes_pls_golite062009
NAD or NADH binding 0.0664389065992004 bayes_pls_golite062009
ion transmembrane transporter activity 0.0257250793986203 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle