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Protein Overview: CE06652

General Information:
Name(s) found: CE06652 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00014095 locus:gdh-1 Glutamate dehydrogenase status:Confirmed UniProt:Q23621 protein_id:CAA98074.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 536 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: positive regulation of growth rate [IMPLink to PubMed article]
    cellular amino acid metabolic process [IEALink to PubMed article]
    Molecular Function: oxidoreductase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSTLSRGAR SVAVRSYSAA TLDAHSQVLD EQKPMEEQVN PSFYKMVDFY FNKGAEVIAP  60
   61 KLAEELKSNS LSQKDKKNLV SGILGAIKPV NKVLYITFPI RRDNGEFEVI EAWRAQHSEH 120
  121 RTPTKGGIRY SLDVCEDEVK ALSALMTYKC AVVDVPFGGA KGGVKIDPKQ YTDYEIEKIT 180
  181 RRIAIEFAKK GFLGPGVDVP APDMGTGERE MGWIADTYAQ TIGHLDRDAS ACITGKPIVS 240
  241 GGIHGRVSAT GRGVWKGLEV FTNDADYMKM VGLDTGLAGK TAIIQGFGNV GLHTHRYLHR 300
  301 AGSKVIGIQE YDCAVYNPDG IHPKELEDWK DANGTIKNFP GAKNFDPFTE LMYEKCDIFV 360
  361 PAACEKSIHK ENASRIQAKI IAEAANGPTT PAADRILLAR GDCLIIPDMY VNSGGVTVSY 420
  421 FEWLKNLNHV SYGRLTFKYD EEANKMLLAS VQESLSKAVG KDCPVEPNAA FAAKIAGASE 480
  481 KDIVHSGLEY TMQRSGEAII RTAHKYNLGL DIRTAAYANS IEKVYNTYRT AGFTFT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-1 hcp1 IP from december2004 Cheeseman, I.M., et al. (2005)
    View Run hcp-2 hcp2 ip from december Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..536] PSI-BLAST 141.0 Glutamate dehydrogenase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • malate dehydrogenase activity
    		•  4.54055877372572 bayes_pls_golite062009
  • glutamate dehydrogenase (NADP+) activity
    		•  4.50065200228697 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
    		•  4.08697502437308 bayes_pls_golite062009
  • oxidoreductase activity
    		•  3.54983447672782 bayes_pls_golite062009
  • malic enzyme activity
    		•  3.35473342014292 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  2.66605122152932 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
    		•  2.66329970371321 bayes_pls_golite062009
  • retinol dehydrogenase activity
    		•  2.20121263385992 bayes_pls_golite062009
  • glutamate dehydrogenase [NAD(P)+] activity
    		•  2.15778057341677 bayes_pls_golite062009
  • catalytic activity
    		•  2.0643953589843 bayes_pls_golite062009
  • shikimate 5-dehydrogenase activity
    		•  1.82286236344978 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH
    		•  1.81060491890041 bayes_pls_golite062009
  • binding
    		•  1.77370305872094 bayes_pls_golite062009
  • DNA binding
    		•  1.61355789916908 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.55390653047158 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  1.54527841865655 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.48478425318425 bayes_pls_golite062009
  • malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity
    		•  1.3195473694323 bayes_pls_golite062009
  • transcription factor activity
    		•  0.91090893050278 bayes_pls_golite062009
  • transporter activity
    		•  0.793769336118517 bayes_pls_golite062009
  • structural molecule activity
    		•  0.75267483298133 bayes_pls_golite062009
  • steroid dehydrogenase activity
    		•  0.688300591674961 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.635891484075352 bayes_pls_golite062009
  • ethanol binding
    		•  0.60130343317805 bayes_pls_golite062009
  • receptor activity
    		•  0.591732115418164 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  0.565177620701637 bayes_pls_golite062009
  • retinol binding
    		•  0.52675367288453 bayes_pls_golite062009
  • protein binding
    		•  0.507836099271263 bayes_pls_golite062009
  • steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  0.48368946932774 bayes_pls_golite062009
  • signal transducer activity
    		•  0.384212208916324 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.384212208916324 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.300373102236296 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.239024094835991 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.165260811069909 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  0.0992243118937675 bayes_pls_golite062009
  • NAD or NADH binding
    		•  0.0664389065992004 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.0257250793986203 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.66

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle