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Protein Overview: rpn-12

General Information:
Name(s) found: rpn-12 / CE06608 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00004468 locus:rpn-12 26S proteasome non-ATPase regulatory subunit 8 status:Confirmed UniProt:Q23449 protein_id:CAA93778.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 250 amino acids

    Gene Ontology:
    Cellular Component: proteasome regulatory particle [ISSLink to PubMed article]
    Biological Process: determination of adult lifespan [IMP]
    proteolysis [IEALink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAAHKNLLA VWAKEPKDLV AVEKALNELT KVLSASSDLN DKQSALASKD LYEISVLLAI  60
   61 LKHDFETFDD YINQMHTYYT MAPENSENKH LMTGLHLMFL LAANRLSDFH MLLEQIPQKE 120
  121 QTSNAYISTP VRIEQSLMEG AYNKVVLTEK NIPSPFYTIF IRIMLDTIRR EIATSIEKSF 180
  181 KVLTAKDATV MLLFDNDEQM KKFGQERKWH LDGERYVFEI EVAQEKPVNL DTVRVATQTL 240
  241 FYAKQLEQIV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..250] FFAS03 2.05 Crystal Structure of Human eIF3k

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.76236644111948 bayes_pls_golite062009
  • hydrolase activity
    		•  2.62777210765927 bayes_pls_golite062009
  • protein binding
    		•  1.5114863464349 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.08079130332447 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.06350696248374 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.700922242779288 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.37240198519167 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.224432853777564 bayes_pls_golite062009
  • DNA binding
    		•  0.180353635969032 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.147335771550418 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  0.142921675412538 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  0.124542865343065 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle